亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
最近中文字幕MV免费高清动漫,在线播放连续内射爽翻天vol
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-Estrogen Receptor alpha/Cy7 Conjugated antibody (bs-0122R-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-0122R-Cy7
英文名稱 Rabbit Anti-Estrogen Receptor alpha/Cy7 Conjugated antibody
中文名稱 Cy7標記的雌激素受體α抗體
別    名 Estradiol receptor; Estrogen receptor alpha; Estradiol Receptor-alpha; Estrogen Receptor 1; Atherosclerosis, susceptibility to, included; DKFZp686N23123; ER Alpha; ER; ER-alpha; ERalpha; ER[a]; Era; ESR; ESR1; ESR1_HUMAN; ESR2; ESRA; Estr; Estrogen receptor 1 (alpha); Estrogen resistance, included; HDL cholesterol, augmented response of, to hormone replacement, included; Myocardial infarction, susceptibility to, included; NR3A1; Nuclear receptor subfamily 3 group A member 1; OTTHUMP00000017718; OTTHUMP00000017719; RNESTROR.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  免疫學  生長因子和激素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,  (predicted: Mouse, Rat, Dog, Cow, Rabbit, )
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 67kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from the middle of human Estrogen Receptor alpha
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Estrogen and progesterone receptor are members of a family of transcription factors that are regulated by the binding of their cognate ligands. The interaction of hormone-bound estrogen receptors with estrogen responsive elements(EREs) alters transcription of ERE-containing genes. The carboxy terminal region of the estrgen receptor contains the ligand binding domain, the amino terminus serves as the transactivation domain, and the DNA binding domain is centrally located. Two forms of estrogen receptor have been identified, ER Alpha and ER Beta. ER Alpha and ER Beta have been shown to be differentially activated by various ligands. The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor (hPR-A and hPR-B), which arise from alternative splicing. In most cells, hPR-B functions as a transcriptional activator of progesterone-responsive gene, whereas hPR-A function as a transcriptional inhibitor of all steroid hormone receptors.

Function:
Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

Subunit:
Interacts with SLC30A9 (By similarity). Binds DNA as a homodimer. Can form a heterodimer with ESR2. Interacts with NCOA3, NCOA5 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Interacts with NCOA7 in a ligand-inducible manner. Interacts with PHB2, PELP1 and UBE1C. Interacts with AKAP13. Interacts with CUEDC2. Interacts with KDM5A. Interacts with SMARD1. Interacts with HEXIM1 and MAP1S. Interacts with PBXIP1. Interaction with MUC1 is stimulated by 7 beta-estradiol (E2) and enhances ERS1-mediated transcription. Interacts with DNTTIP2, FAM120B and UIMC1. Interacts with isoform 4 of TXNRD1. Interacts with MLL2. Interacts with ATAD2 and this interaction is enhanced by estradiol.

Subcellular Location:
Nucleus.

Post-translational modifications:
Phosphorylated by cyclin A/CDK2. Phosphorylation probably enhances transcriptional activity.
Glycosylated; contains N-acetylglucosamine, probably O-linked.

Similarity:
Belongs to the nuclear hormone receptor family. NR3 subfamily.
Contains 1 nuclear receptor DNA-binding domain.

Database links:

Entrez Gene: 407238 Cow

Entrez Gene: 403640 Dog

Entrez Gene: 2099 Human

Entrez Gene: 13982 Mouse

Entrez Gene: 24890 Rat

Omim: 133430 Human

SwissProt: P49884 Cow

SwissProt: P03372 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

類固醇受體(Steroid Receptors)
雌激素受體ER-α(Estrogen Receptor-α, ERα)是一類位于細胞表面或細胞內(nèi)的特異性蛋白質(zhì)。
某些特異的雌激素、雌激素類似物、衍生物、拮抗劑或阻斷劑與它結(jié)合后可引發(fā)或阻斷受體蛋白質(zhì)的轉(zhuǎn)化作用。并將雌激素-受體復(fù)合物從細胞質(zhì)再定位進入細胞核以啟動蛋白質(zhì)的生物合成。
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
高清一区二区三区日本久 | 综合欧美亚洲日本一区 | 99在线精品国自产拍中文字幕 | 欧美性生恔XXXXXDDDD | 一级成人欧美一区在线观看 | 在线观看日本一区 | 亚洲 色无码专区在线 | 99久久精品国产高清一区二区 | 欧美亚洲性色影视在线 | 精品免费囯产一区二区三区四区 | 日韩mv国产mv网站永久 | 男男体育生乱yin高H肉汁 | 国产一区二区免费在线观看 | 精品视频一区二区三区中文字幕 | 精品国产亚洲AV麻豆 | 国产精品免费久久久久三级无码 | 日韩一卡2卡3卡4卡新区亚洲 | 天堂资源中文最新版在线一区 | 亚洲AV无码专区一级婬片毛片 | 国产欧美精品亚洲日本一区 | 91精品国产综合久久精品色欲 | 欧美日韩国产码综合一区在线 | 性生生活色欲片性按摩 | 亚洲美女又黄又爽在线观看 | 一性一交一伦一色一按—摩 | 国产成人福利美女观看视频 | 国产探花在线精品一区二区 | 欧美一级做a爰片免费 | 亚洲国产精品嫩草影院永久 | 无码国产色欲XXXX视频 | 欧美最猛黑人xxxx黑人猛交 | 日韩视频高清免费看 | 午夜精品一区二区三区在线观看 | 久久夜色撩人精品国产小说 | 国产在线精彩视频 | 忘忧草日本在线播放WWW | 男插女高潮一区二区 | 色欲aⅴ精品一区二区三区浪潮 | 国产精品视频一区二区猎奇 | 久久黄色免费网站 | 最近中文字幕2018免费版2019 |