亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
人妻仑乱少妇88MAV,日韩精品无码一区二区免费A片
Rabbit Anti-IDH2/Gold Conjugated antibody (bs-3947R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-3947R-Gold
英文名稱 Rabbit Anti-IDH2/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的草酰琥珀酸脫羧酶抗體
別    名 mitochondrial; ICD-M; IDH; IDH2; IDHP_HUMAN; IDP; Isocitrate dehydrogenase [NADP]; Isocitrate dehydrogenase [NADP], mitochondrial; mNADP-IDH; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 腫瘤  細胞生物  免疫學(xué)  染色質(zhì)和核信號  轉(zhuǎn)錄調(diào)節(jié)因子  激酶和磷酸酶  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Rat,  (predicted: Mouse, Dog, Horse, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 51kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IDH2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
IDH2 (isocitrate dehydrogenase 2 (NADP+), mitochondrial), also designated NADP+-specific ICDH; isocitrate dehydrogenase, mitochondrial; and oxalosuccinate decarboxylase, is a 452 amino acid enzyme encoded by the human gene IDH2. IDH2 belongs to the isocitrate and isopropylmalate dehydrogenases family and contains two nucleotide binding regions. IDH2 is involved in the reduction of NADP+ to NADPH and maintains the supply of glutathione (GSH) in mitochondria. It is believed to play a role in intermediary metabolism and energy production. IDH2 also tightly associates with the pyruvate dehydrogenase complex. IDH2 is found in the mitochondrion as a homodimer and can bind one magnesium or manganese ion per subunit.

Function:
Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex.

Subunit:
Homodimer.

Subcellular Location:
Cytoplasm. Peroxisome.

DISEASE:
Defects in IDH1 are involved in the development of glioma (GLM) [MIM:137800]. Gliomas are central nervous system neoplasms derived from glial cells and comprise astrocytomas, glioblastoma multiforme, oligodendrogliomas, and ependymomas. Note=Mutations affecting Arg-132 are tissue-specific, and suggest that this residue plays a unique role in the development of high-grade gliomas. Mutations of Arg-132 to Cys, His, Leu or Ser abolish magnesium binding and abolish the conversion of isocitrate to alpha-ketoglutarate. Instead, alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate. Elevated levels of R(-)-2-hydroxyglutarate are correlated with an elevated risk of malignant brain tumors.

Similarity:
Belongs to the isocitrate and isopropylmalate dehydrogenases family.

Database links:

Entrez Gene: 3418 Human

Entrez Gene: 269951 Mouse

Entrez Gene: 361596 Rat

Omim: 147650 Human

SwissProt: P48735 Human

SwissProt: P54071 Mouse

SwissProt: P56574 Rat

Unigene: 596461 Human

Unigene: 246432 Mouse

Unigene: 290925 Mouse

Unigene: 3490 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

IDH2又稱異檸檬酸脫氫酶,他有有兩種類型的酶:以NAD為輔酶的酶(EC1.1.1.41)和NADP的酶(EC1.1.1.42),兩者催化同一反應(yīng)。在胞漿中以NADP為輔酶,在線粒體內(nèi)膜以NAD為輔酶。    IDH2在三羧酸循環(huán)中正常起作用的是NAD為輔酶的酶,他是提供為ADP激活的變構(gòu)酶。
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
国产精品永久在线 | 国产高潮婬乱叫床一区二区 | 欧美最猛激情性AAAAA | 中文字幕无码a级毛片 | 免费女人18a级毛片视频 | 亚欧成人毛片一区二区三区四区 | 公交车掀开奶罩边躁狠狠躁视频 | 美女裸身露双奶头无遮挡免费视频 | 老熟妇一区二区三区啪啪 | 内射一区二区精品视频在线观看 | 国产精品天天影视久久综合网 | 中文字幕日韩一区二区不卡 | 国产午夜无码91精品免费看 | √天堂中文在线最新版 | 亚洲黄色网站免费观看 | 久久久久精品国产AV无码 | 久久天天躁狠狠躁夜夜躁2012 | 久久免费少妇高潮久久精品99 | 成人毛片100免费观看 | 精品国产人成亚洲区 | 97se亚洲综合自在线尤物 | 欧美成a人片免费看久久 | 欧亚成年男女深夜百度网盘 | 亚洲综合AV在线在线播放 | 欧美.日韩.日本国产视频 | 50岁老熟女露脸25分钟91 | 推油少妇久久99久久99久久 | 青青草97国产精品免费观看 | 久久国产精品自线拍免费 | 国产又黄又爽又猛免费app | 亚洲午夜福利在线视频 | 亚洲调教自慰喷水AV无码 | 永久黄网站色视频免费无下载 | 毛片免费全部免费观看 | 亚洲人成色777777在线观看 | 水蜜桃AV无码专区亚洲AV麻豆 | 教室啪啪高挑长腿正在播放 | 蜜桃视频无码区在线观看 | 伊人久久大香线蕉AV超碰 | 台湾一级毛片永久免费 | 一女侍七夫巨H双修 |