亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
精品一级 片内射视网站,国产成人精品免高潮费视频频
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-IDH2/BF647 Conjugated antibody (bs-3947R-BF647)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-3947R-BF647
英文名稱 Rabbit Anti-IDH2/BF647 Conjugated antibody
中文名稱 BF647標記的草酰琥珀酸脫羧酶抗體
別    名 mitochondrial; ICD-M; IDH; IDH2; IDHP_HUMAN; IDP; Isocitrate dehydrogenase [NADP]; Isocitrate dehydrogenase [NADP], mitochondrial; mNADP-IDH; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細胞生物  免疫學(xué)  染色質(zhì)和核信號  轉(zhuǎn)錄調(diào)節(jié)因子  激酶和磷酸酶  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Rat,  (predicted: Mouse, Dog, Horse, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 51kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IDH2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
IDH2 (isocitrate dehydrogenase 2 (NADP+), mitochondrial), also designated NADP+-specific ICDH; isocitrate dehydrogenase, mitochondrial; and oxalosuccinate decarboxylase, is a 452 amino acid enzyme encoded by the human gene IDH2. IDH2 belongs to the isocitrate and isopropylmalate dehydrogenases family and contains two nucleotide binding regions. IDH2 is involved in the reduction of NADP+ to NADPH and maintains the supply of glutathione (GSH) in mitochondria. It is believed to play a role in intermediary metabolism and energy production. IDH2 also tightly associates with the pyruvate dehydrogenase complex. IDH2 is found in the mitochondrion as a homodimer and can bind one magnesium or manganese ion per subunit.

Function:
Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex.

Subunit:
Homodimer.

Subcellular Location:
Cytoplasm. Peroxisome.

DISEASE:
Defects in IDH1 are involved in the development of glioma (GLM) [MIM:137800]. Gliomas are central nervous system neoplasms derived from glial cells and comprise astrocytomas, glioblastoma multiforme, oligodendrogliomas, and ependymomas. Note=Mutations affecting Arg-132 are tissue-specific, and suggest that this residue plays a unique role in the development of high-grade gliomas. Mutations of Arg-132 to Cys, His, Leu or Ser abolish magnesium binding and abolish the conversion of isocitrate to alpha-ketoglutarate. Instead, alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate. Elevated levels of R(-)-2-hydroxyglutarate are correlated with an elevated risk of malignant brain tumors.

Similarity:
Belongs to the isocitrate and isopropylmalate dehydrogenases family.

Database links:

Entrez Gene: 3418 Human

Entrez Gene: 269951 Mouse

Entrez Gene: 361596 Rat

Omim: 147650 Human

SwissProt: P48735 Human

SwissProt: P54071 Mouse

SwissProt: P56574 Rat

Unigene: 596461 Human

Unigene: 246432 Mouse

Unigene: 290925 Mouse

Unigene: 3490 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

IDH2又稱異檸檬酸脫氫酶,他有有兩種類型的酶:以NAD為輔酶的酶(EC1.1.1.41)和NADP的酶(EC1.1.1.42),兩者催化同一反應(yīng)。在胞漿中以NADP為輔酶,在線粒體內(nèi)膜以NAD為輔酶。    IDH2在三羧酸循環(huán)中正常起作用的是NAD為輔酶的酶,他是提供為ADP激活的變構(gòu)酶。
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
热热久久超碰精品中文字幕 | 精品国产乱码久久久久久浪潮 | 一个人看的免费视频大全在线观看 | 亚洲一区二区三区免费 | 99九九精品国产高清自在线 | 精品久久BBBBB精品人妻 | 成 人 免 费 黄 色 网站无毒下载 | 91精品手机国产在线播放 | 国产超碰人人爱被IOS解锁 | 亚洲精品无码久久久久苍井空 | 中文字幕乳桑田授乳奶水电影 | 四虎影视成人永久免费观看视频 | 成人满18在线观看网站免费 | 99爱在线精品视频免费观看9 | 国产在线观看免费观看不卡 | 思思久久好好热精品国产 | 国产精品亚洲专区在线播放 | 精品日韩二区三区精品视频 | 日韩欧美群交P片內射中文 高潮又爽又大又黄无遮挡免费 | 国产欧美一区二区精品性色超碰 | 日本亚洲一区二区三区 | 午夜剧场1000 | 欧美激情视频二区 | 日韩欧美国产丝袜大香蕉 | 国产成人手机高清在线观看网站 | 国产99久久久国产精品潘金莲 | 一本久道综合在线无码人妻 | 亚洲午夜AAA级久久久久 | 亚洲精品午夜久久久久久久久 | 中国少妇BBWBBW牲交 | 欧美R级荡公乱妇在线观看 免费看的一级毛片 | 亚洲国产精品无码久久久久久曰 | 妖精视频一区二区免费 | 欧美乱码精品一区二区三区卡 | 任我鲁精品视频精品 | 久久se精品一区精品二区 | JEALOUSVUE极品少妇 | sg99.xy丝瓜视频 | A级毛片无码久久精品免费 九九视频精品全部免费播放 | 国产男女性潮高清免费网站 | 一本久到久久亚洲综合 |