亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
亚洲色欲色欲77777小说,97在线精品视频免费
Rabbit Anti-IRGM/Cy5 Conjugated antibody (bs-4015R-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-4015R-Cy5
英文名稱 Rabbit Anti-IRGM/Cy5 Conjugated antibody
中文名稱 Cy5標(biāo)記的免疫相關(guān)鳥苷三磷酸酶基因抗體
別    名 Irgm; IFI1; Iigp3; Immunity related GTPase family M protein 1; Immunity related GTPase family, M; Interferon inducible protein 1; IRGM1; LRG 47; LRG47; IRGM_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  b-淋巴細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 20kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IRGM (62-105aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
IRGM belongs to a family of interferon-gamma inducible GTPases, belonging to the GTPase superfamily, and are selectively induced by IFN-gamma or bacterial lipopolysaccharide (LPS) stimulation. IRGM is primarily expressed in all cells derived from B-cell lineages, and is highly expressed in macrophages following IFN-gamma stimulation. IRGM has been shown to be required for host defences against a broad range of intracellular pathogens. Specifically, IRGM deficient mice show defects with intracellular microbial killing, phagosome maturation and autophagy. More recently IRGM has been shown to inhibit baseline hematopoietic proliferation and is required for a normal hematopoietic stem cell response to chemical and infectious stimuli.

Function:
Putative GTPase which is required for clearance of acute protozoan and bacterial infections. Functions in innate immune response probably through regulation of autophagy. May regulate proinflammatory cytokine production and prevent endotoxemia upon infection. May also play a role in macrophages adhesion and motility (By similarity).

Subcellular Location:
Golgi apparatus membrane. Cell membrane. Cytoplasmic vesicle, phagosome membrane. Cytoplasmic vesicle, autophagosome membrane. Cell projection, phagocytic cup.

Tissue Specificity:
Widely expressed (at protein level). Expressed in several tissues including colon, small bowel and peripheral blood leukocytes.

DISEASE:
Defects in IRGM are the cause of susceptibility to inflammatory bowel disease type 19 (IBD19) [MIM:612278]. A chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology. It is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may affect any part of the gastrointestinal tract from the mouth to the anus, but most frequently it involves the terminal ileum and colon. Bowel inflammation is transmural and discontinuous; it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers; fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints.

Similarity:
Belongs to the interferon-inducible GTPase family.

Database links:
UniProtKB/Swiss-Prot: A1A4Y4.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

IRGM(又稱干擾素誘導(dǎo)蛋白1)屬于γ-干擾素誘導(dǎo)的GTP酶家族的一種,是一種復(fù)活基因,目前主要用于克羅恩氏病(一種腸道的自身免疫性疾?。┑难芯?。
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
国产高清乱码又大又圆 | 日本一道高清一区二区三区 | 国产精品国产三级国产AV麻豆 | 欧美被狂躁喷白浆精品 | 色欲国产麻豆一精品一AV一免费 | 99久久国产宗和精品1上映 | 久久人人爽人人爽人人片AV浪潮 | 秋葵视频ios无限制解码免费版下载 | 又大又爽又硬的曰皮视频 | 97夜夜澡人人爽人人喊中国片 | 亚洲精品宾馆在线精品酒店 | 肉到痉挛中出痴汉在线播放 | 欧美叉叉叉BBB网站 久久精品视频91 | 中国一级免费毛片 | 日韩一区二区在线观看视频 | 中韩高清无专码区2021曰 | 亚洲乱码国产乱码精品精乡村 | 四虎影视永久在线观看 | 黄片视频在线免费观看 | 黄色视频网站在线免费观看 | 激情动图欧美一区二区 | 91精品国产91久久久久久青草 | 日韩精品一区二区三区中文不卡 | 亚洲精品ty久久久久久久久久 | 精品国产亚洲AV麻豆 | 亚裔美女被黑人巨大进入 | 精品少弄得99久久精品区别 | 无码人妻精品中文字幕 | 欧美黑人肉体狂欢交换大派对 | 久久夜色撩人精品国产小说 | 牛牛影视午夜免费福利 | 国产又粗又猛又爽又黄的视频免费软件 | 一区二区三区日韩免费播放 | 日韩AV无码专区国产乱码 | 99re热线精品视频 | 久久这里只有精品视频6 | 亚州日本乱码一区二区三区 | 一本大道香蕉久在线播放29 | 免费精品国自产拍在线播放 | 无码人妻免费—区二区三 | 国产在线观看免费一级 |