亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国产精品无码午夜福利免费看,亚欧精品一区二区三区四区,麻豆人妻少妇精品无码区
Rabbit Anti-IRGM/BF488 Conjugated antibody (bs-4015R-BF488)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-4015R-BF488
英文名稱 Rabbit Anti-IRGM/BF488 Conjugated antibody
中文名稱 BF488標(biāo)記的免疫相關(guān)鳥苷三磷酸酶基因抗體
別    名 Irgm; IFI1; Iigp3; Immunity related GTPase family M protein 1; Immunity related GTPase family, M; Interferon inducible protein 1; IRGM1; LRG 47; LRG47; IRGM_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  b-淋巴細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 20kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IRGM (62-105aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
IRGM belongs to a family of interferon-gamma inducible GTPases, belonging to the GTPase superfamily, and are selectively induced by IFN-gamma or bacterial lipopolysaccharide (LPS) stimulation. IRGM is primarily expressed in all cells derived from B-cell lineages, and is highly expressed in macrophages following IFN-gamma stimulation. IRGM has been shown to be required for host defences against a broad range of intracellular pathogens. Specifically, IRGM deficient mice show defects with intracellular microbial killing, phagosome maturation and autophagy. More recently IRGM has been shown to inhibit baseline hematopoietic proliferation and is required for a normal hematopoietic stem cell response to chemical and infectious stimuli.

Function:
Putative GTPase which is required for clearance of acute protozoan and bacterial infections. Functions in innate immune response probably through regulation of autophagy. May regulate proinflammatory cytokine production and prevent endotoxemia upon infection. May also play a role in macrophages adhesion and motility (By similarity).

Subcellular Location:
Golgi apparatus membrane. Cell membrane. Cytoplasmic vesicle, phagosome membrane. Cytoplasmic vesicle, autophagosome membrane. Cell projection, phagocytic cup.

Tissue Specificity:
Widely expressed (at protein level). Expressed in several tissues including colon, small bowel and peripheral blood leukocytes.

DISEASE:
Defects in IRGM are the cause of susceptibility to inflammatory bowel disease type 19 (IBD19) [MIM:612278]. A chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology. It is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may affect any part of the gastrointestinal tract from the mouth to the anus, but most frequently it involves the terminal ileum and colon. Bowel inflammation is transmural and discontinuous; it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers; fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints.

Similarity:
Belongs to the interferon-inducible GTPase family.

Database links:
UniProtKB/Swiss-Prot: A1A4Y4.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

IRGM(又稱干擾素誘導(dǎo)蛋白1)屬于γ-干擾素誘導(dǎo)的GTP酶家族的一種,是一種復(fù)活基因,目前主要用于克羅恩氏病(一種腸道的自身免疫性疾?。┑难芯俊?
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
欧美人与拘牲交大全O人禾 天天躁日日躁狠狠躁日日躁黑人 | 欧美性大战xxxxx久久久 | 日日噜噜噜夜夜爽爽狠狠 | 亚洲AV无一区二区三区久久 | 国产情侣真实露脸在线 | 国产在线一区观看 | 免费国产黄网站在线观看可以下载 | 久久人做人爽一区二区三区 | 午夜男女爽爽爽免费播放 | 最近免费中文字幕大全高清大全1 | 少妇又紧又色又爽又刺激视频 | 久久久久亚洲AV成人人人 | 光棍天堂2019在线 | 国内精品久久久久久久999下 | 久久久久久久久久久久无码 | 久99久精品视频免费观看v | 2020精品极品国产色在线观看 | 又紧又大又爽精品一区二区 | 成片免费观看视频潢片 | 蜜臀亚洲AV永久无码精品老司机 | 日韩久久精品无码一二级 | bbbbbxxxxx精品人 | 最近中文字幕免费高清mv视频 | 91天堂最新在线观看 | 国产乱码一二三区精品 | 九九热线有精品免费观看 | 大学生高潮无套内谢视频 | 丰满老女人一级毛片视频 | 又长又大又粗又硬3p免费视频 | 俄罗斯aaaa一级毛片 | 久久久综合亚洲色一区二区三区 | 国产高潮婬乱叫床一区二区 | 国产亚洲欧美日韩综合一区在线观看 | 精品无码国产拍自产拍在线 | 两根撑到极致哭着求饶h | 恩恩呜呜好大好爽快点 | 可以在线看av的网站 | 午夜无码片在线观看影院 | 久久久精品2019免费观看 | 亚洲成av人影院 | 国产AV无码专区毛片 |