亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
少妇人妻偷人精品视蜜桃 ,欧美精品精品一区在线发布,乱欧人与牲口杂交暴力狂
Rabbit Anti-G protein alpha S/NESP55/Cy5 Conjugated antibody (bs-3939R-Cy5)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-3939R-Cy5
英文名稱(chēng) Rabbit Anti-G protein alpha S/NESP55/Cy5 Conjugated antibody
中文名稱(chēng) Cy5標(biāo)記的G蛋白αS抗體(鳥(niǎo)嘌呤核苷酸結(jié)合蛋白Gα s)
別    名 Adenylate cyclase stimulating G alpha protein; AHO; Alternative gene product encoded by XL exon; Extra large alphas protein; GNAS; GNAS complex locus; GNAS1; GPSA; Gs alpha subunit; GSA; GSP; Guanine nucleotide binding protein (G protein) alpha stimulating activity polypeptide 1; Guanine nucleotide binding protein alpha stimulating activity polypeptide 1; Guanine nucleotide binding protein G(s) subunit alpha isoforms short; Guanine nucleotide binding protein G(s) subunit alpha isoforms XLas; Guanine nucleotide regulatory protein; MGC33735; NESP; NESP55; Neuroendocrine secretory protein; PHP1A; PHP1B; POH; Protein ALEX; SCG6; Secretogranin VI; XLalphas; XLas; C20orf45; dJ309F20.1.1; dJ806M20.3.3; GNAS1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  結(jié)合蛋白  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Danio rerio)
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 111kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human G protein alpha S
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The Gs protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli.

Function:
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. XLas isoforms interact with the same set of receptors as Gnas isoforms (By similarity).

Subunit:
G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts through its N-terminal region with ALEX which is produced from the same locus in a different open reading frame. This interaction may inhibit its adenylyl cyclase-stimulating activity (By similarity).

Subcellular Location:
Cell membrane; Peripheral membrane protein.

DISEASE:
Defects in GNAS are the cause of GNAS hyperfunction (GNASHYP) [MIM:139320]. This condition is characterized by increased trauma-related bleeding tendency, prolonged bleeding time, brachydactyly and mental retardation. Both the XLas isoforms and the ALEX protein are mutated which strongly reduces the interaction between them and this may allow unimpeded activation of the XLas isoforms.
Defects in GNAS are a cause of ACTH-independent macronodular adrenal hyperplasia (AIMAH) [MIM:219080]; also known as adrenal Cushing syndrome due to AIMAH. A rare adrenal defect characterized by multiple, bilateral, non-pigmented, benign, adrenocortical nodules. It results in excessive production of cortisol leading to ACTH-independent Cushing syndrome. Clinical manifestations of Cushing syndrome include facial and trunkal obesity, abdominal striae, muscular weakness, osteoporosis, arterial hypertension, diabetes.
Genetic variations in GNAS are the cause of pseudohypoparathyroidism type 1B (PHP1B) [MIM:603233]. PHP1B is characterized by parathyroid hormone (PTH)-resistant hypocalcemia and hyperphosphatemia. Patients affected with PHP1B have normal activity of the product of GNAS, lack developmental defects characteristic of AHO, and typically show no other endocrine abnormalities besides resistance to PTH. Note=Most affected individuals have defects in methylation of the gene. In some cases microdeletions involving the STX16 appear to cause loss of methylation at exon A/B of GNAS, resulting in PHP1B. Paternal uniparental isodisomy have also been observed.
Defects in GNAS are the cause of pseudohypoparathyroidism type 1C (PHP1C) [MIM:612462]. It is a disorder characterized by end-organ resistance to parathyroid hormone, hypocalcemia and hyperphosphatemia. It is commonly associated with Albright hereditary osteodystrophy whose features are short stature, obesity, round facies, short metacarpals and ectopic calcification.

Similarity:
Belongs to the G-alpha family. G(s) subfamily. membrane protein.

Database links:

Entrez Gene: 281793 Cow

Entrez Gene: 2778 Human

Entrez Gene: 14683 Mouse

Entrez Gene: 100049657 Pig

Entrez Gene: 24896 Rat

Omim: 139320 Human

SwissProt: P04896 Cow

SwissProt: P63091 Dog

SwissProt: P63092 Human

SwissProt: P84996 Human

SwissProt: Q5JWF2 Human

SwissProt: P63094 Mouse

SwissProt: Q6R0H7 Mouse

SwissProt: P29797 Pig

SwissProt: P63095 Rat

SwissProt: Q63803 Rat

Unigene: 125898 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
老头埋进校花里面使劲添 | 向日葵视频APP秋葵榴莲在线 | 中文字幕日本一区 | 亚洲和欧洲一码二码区别7777 | 一级内射片在线网站观看 | 绯色av入口一区二区三区 | 捣烂宫口np失禁哭张开了h | 色伦专区97中文字幕 | 国产成人精品无缓存在线播放 | 日本丰满熟妇被捏出奶水 | 一二三四社区在线中文视频 | 91网站永久免费看nba视频 | 国产高清视频免费最新在线 | 久久精品中文騷妇女内射 | 国产日韩欧美另类 | 国产无套粉嫩白浆在线观看 | 中文字幕一级毛片无码视频 | 蜜臀久久精品久久久久酒店 | 国产亚洲成AⅤ人片在线观看 | 色成人网站WWW永久在线观看 | 无码狠狠躁久久久久久久 | 亚洲成AV人在线播放无码 | 国产嫖妓一区二区三区无码 | 亚洲AV综合色区无码三区30p | 国产真人无遮挡作爱免费视频 | 无码av高清毛片在线看 | 国产AV无码专区亚洲A∨毛片 | 国产精品久久久久久久久久影院 | 亚洲调教自慰喷水AV无码 | YW193.CAN尤物国产在线网页 | 91精品国产综合久久精品色欲 | 蜜桃TV成人网站免费打开 | 永久免费观看的黄网站 | 熟女自慰白浆一区二区 | 免费无遮挡无码视频在线观看洗澡 | 国产午夜激无码Av片在线观看 | 日本高清在线天码一区播放 | 国产乱妇乱子在线播放视频 | 国产精品视频一区国模私拍 | 永久免费毛片在线播放 | 最新国产毛2卡3卡4卡 |