亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
丰满老熟好大bbb,欧美激情欲高潮视频在线观看,91在线视频免费播放
Rabbit Anti-G protein alpha S/NESP55/BF594 Conjugated antibody (bs-3939R-BF594)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-3939R-BF594
英文名稱 Rabbit Anti-G protein alpha S/NESP55/BF594 Conjugated antibody
中文名稱 BF594標(biāo)記的G蛋白αS抗體(鳥嘌呤核苷酸結(jié)合蛋白Gα s)
別    名 Adenylate cyclase stimulating G alpha protein; AHO; Alternative gene product encoded by XL exon; Extra large alphas protein; GNAS; GNAS complex locus; GNAS1; GPSA; Gs alpha subunit; GSA; GSP; Guanine nucleotide binding protein (G protein) alpha stimulating activity polypeptide 1; Guanine nucleotide binding protein alpha stimulating activity polypeptide 1; Guanine nucleotide binding protein G(s) subunit alpha isoforms short; Guanine nucleotide binding protein G(s) subunit alpha isoforms XLas; Guanine nucleotide regulatory protein; MGC33735; NESP; NESP55; Neuroendocrine secretory protein; PHP1A; PHP1B; POH; Protein ALEX; SCG6; Secretogranin VI; XLalphas; XLas; C20orf45; dJ309F20.1.1; dJ806M20.3.3; GNAS1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  結(jié)合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Danio rerio)
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 111kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human G protein alpha S
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The Gs protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli.

Function:
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. XLas isoforms interact with the same set of receptors as Gnas isoforms (By similarity).

Subunit:
G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts through its N-terminal region with ALEX which is produced from the same locus in a different open reading frame. This interaction may inhibit its adenylyl cyclase-stimulating activity (By similarity).

Subcellular Location:
Cell membrane; Peripheral membrane protein.

DISEASE:
Defects in GNAS are the cause of GNAS hyperfunction (GNASHYP) [MIM:139320]. This condition is characterized by increased trauma-related bleeding tendency, prolonged bleeding time, brachydactyly and mental retardation. Both the XLas isoforms and the ALEX protein are mutated which strongly reduces the interaction between them and this may allow unimpeded activation of the XLas isoforms.
Defects in GNAS are a cause of ACTH-independent macronodular adrenal hyperplasia (AIMAH) [MIM:219080]; also known as adrenal Cushing syndrome due to AIMAH. A rare adrenal defect characterized by multiple, bilateral, non-pigmented, benign, adrenocortical nodules. It results in excessive production of cortisol leading to ACTH-independent Cushing syndrome. Clinical manifestations of Cushing syndrome include facial and trunkal obesity, abdominal striae, muscular weakness, osteoporosis, arterial hypertension, diabetes.
Genetic variations in GNAS are the cause of pseudohypoparathyroidism type 1B (PHP1B) [MIM:603233]. PHP1B is characterized by parathyroid hormone (PTH)-resistant hypocalcemia and hyperphosphatemia. Patients affected with PHP1B have normal activity of the product of GNAS, lack developmental defects characteristic of AHO, and typically show no other endocrine abnormalities besides resistance to PTH. Note=Most affected individuals have defects in methylation of the gene. In some cases microdeletions involving the STX16 appear to cause loss of methylation at exon A/B of GNAS, resulting in PHP1B. Paternal uniparental isodisomy have also been observed.
Defects in GNAS are the cause of pseudohypoparathyroidism type 1C (PHP1C) [MIM:612462]. It is a disorder characterized by end-organ resistance to parathyroid hormone, hypocalcemia and hyperphosphatemia. It is commonly associated with Albright hereditary osteodystrophy whose features are short stature, obesity, round facies, short metacarpals and ectopic calcification.

Similarity:
Belongs to the G-alpha family. G(s) subfamily. membrane protein.

Database links:

Entrez Gene: 281793 Cow

Entrez Gene: 2778 Human

Entrez Gene: 14683 Mouse

Entrez Gene: 100049657 Pig

Entrez Gene: 24896 Rat

Omim: 139320 Human

SwissProt: P04896 Cow

SwissProt: P63091 Dog

SwissProt: P63092 Human

SwissProt: P84996 Human

SwissProt: Q5JWF2 Human

SwissProt: P63094 Mouse

SwissProt: Q6R0H7 Mouse

SwissProt: P29797 Pig

SwissProt: P63095 Rat

SwissProt: Q63803 Rat

Unigene: 125898 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
性色AV一区二区三区V视界影院 | 久久久久久91香蕉国产 | 欧美日韩国产色综合一二三四 | 久久亚洲国产成人综合久久精品 | 国产精品久久久久无码AV色戒 | 国产国拍亚洲精品永久软件 | 日韩高清免费视频观看 | 国产成人手机高清在线观看网站 | WBBBB搡BBBB搡BBBB 美女性爽视频国产免费 | 国产乡下三级全黄三级 | 国产精品久久久久无码AV | 美妇吞吐粗长撞击迎合 | 久久www免费人成高清 | 美女脱18以下禁止看免费 | a久久久久一级毛片护士免费 | 牛牛本精品99久久精品88m | 国产亚洲欧美日韩综合综合二区 | 夜鲁夜鲁很鲁在线视频视频 | 欧美精品在线观看 | 色噜噜人妻丝袜aV先锋影音先 | 18禁美女裸体无遮挡免费观看国产 | 国产无码三级片网址? | 国产剧情AV不卡在线观看 | 特级毛片在线大全免费播放 | 亚洲1区2区3区精华液 | 草莓黄瓜蜜桃视频app下载 | 久久国产精品高潮一级毛片 | 麻豆精品无码国产在线 | 艳妇臀荡乳欲伦69调教视频 | 内射无套在线观看高清完整免费 | XXX2高清在线观看免费视频 | 风流少妇又紧又爽又丰满 | 2021av一二三级视频在线观看亚洲 | 麻豆精品国产自产在线观看 | 人与禽一级一级毛片 | a级高清观看视频在线看 | 40岁成熟女人牲交片 | 激情aa视频试看免费 | 亚洲精品天天影视综合网 | 久久久久久久99精品免费观看 | 少妇真人直播免费视频 |