亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
99久久精品免费看国产一区二区三区 ,91精品国产色综合久久
Rabbit Anti-Glycogen/PE Conjugated antibody (bs-2359R-PE)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-2359R-PE
英文名稱 Rabbit Anti-Glycogen/PE Conjugated antibody
中文名稱 PE標(biāo)記的葡萄糖合成酶1抗體
別    名 Glycogen synthase 1 (muscle); Glycogen synthase 1; GSY; GYS; GYS1; EC 2.4.1.11; Glycogen synthase1; GYS 1; Starchsynthase muscle; UDP glucose glycogen glucosyltransferase; GYS1_HUMAN; Glycogen [starch] synthase, muscl.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  生長因子和激素  轉(zhuǎn)錄調(diào)節(jié)因子  激酶和磷酸酶  糖尿病  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 81kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Glycogen synthase 1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Glycogen Synthase (GS) is a key enzyme in the regulation of glycogen metabolism. GS catalyzes the incorporation of UDP-glucose incorporation into glycogen. The activity of glycogen synthase is regulated by hormonal stimuli (insulin, catecholamines and glucagons) and non-hormonal stimuli (blood glucose level and exercise). Two main isoforms of mammalian GS are designated as muscle (glycogen synthase 1) and liver (glycogen synthase 2). Most tissues express glycogen synthase 1, whereas glycogen synthase 2 appears to be tissue-specific. The two isoforms have 70% identical amino acid sequence. Glycogen synthase can be phosphorylated by multiple kinases including glycogen synthase kinase-3 (GSK-3), mitogen-activated protein kinase-related protein kinase (DYRK), and SAPK2b/p38b which leads to its inactivation.

Function:
Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

Subunit:
Interacts with GYG1.

Post-translational modifications:
Phosphorylation at Ser-8 by AMPK inactivates the enzyme activity. Primed phosphorylation at Ser-657 (site 5) by CSNK2A1 and CSNK2A2 is required for inhibitory phosphorylation at Ser-641 (site 3a), Ser-645 (site 3b), Ser-649 (site 3c) and Ser-653 (site 4) by GSK3A an GSK3B (By similarity). Phosphorylated at Ser-641 by PASK, leading to inactivation; phosphorylation by PASK is inhibited by glycogen. Dephosphorylation at Ser-641 and Ser-645 by PP1 activates the enzyme.

DISEASE:
Defects in GYS1 are the cause of muscle glycogen storage disease type 0 (GSD0b) [MIM:611556]; Metabolic disorder characterized by fasting hypoglycemia presenting in infancy or early childhood. The role of muscle glycogen is to provide critical energy during bursts of activity and sustained muscle work.

Similarity:
Belongs to the glycosyltransferase 3 family.

Database links:

Entrez Gene: 2997 Human

Entrez Gene: 14936 Mouse

Entrez Gene: 690987 Rat

Omim: 138570 Human

SwissProt: P13807 Human

SwissProt: Q8VEB0 Mouse

SwissProt: Q9Z1E4 Mouse

SwissProt: A2RRU1 Rat

Unigene: 386225 Human

Unigene: 275654 Mouse

Unigene: 95278 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
欧美日韩精品一区二区三区高清视频 | 国产一区二区三区内射高清 | 亚裔美女被黑人巨大进入 | 美女无遮挡无打码内射裸身视频 | 国产精品99无码一区二区 | 欧美性一交一乱一伦A片 | 国产免费AV片在线播放唯爱网 | 国产亚洲综合99久久系列 | 无码人妻免费—区二区三 | 国产亚洲综合99久久系列 | 国产女人18毛片水真多 | 久久人人妻人人爽人人爽 | 漂亮人妻被中出中文字幕色 | 国产极品熟女沙发内射AV | 久久综合色天天久久综合图片 | 成人高清视频在线观看大全 | 欧美自拍另类欧美综合图片区 | 欧美激情视频二区 | 亚洲国产精品嫩草影院永久 | 亚洲欧美日韩国产综合五月天 | 日本特级婬片a片免费手机版 | 欧美午夜精品一区二区蜜桃 | 精品人妻大屁股白浆久久 | 调教我的妺妺H肉YIN荡视频 | 久久99蜜桃精品久久久久小说 | 精品欧美一区二区三区成人片在线 | 又大又紧又粗C死你视频 | 亚洲AV综合色一区二区三区 | 国产99视频精品免费视亚洲一级Av无码毛片久久精品 | 少妇人妻上班偷人精品免费 | 免费人成在线观看网站免费观看 | 成人免费视频一区 | 国产精品久久久久久搜索 | 久久香蕉综合一本到3atv | 日韩成人精品视频免费专区 | 精品亚洲一区二区在线播放 | 国内精品一区二区综合欧美 | 久久久综合亚洲色一区二区三区 | 波多野结衣av一区二区全免费观看 | 国产午夜片无码区在线观看爱情网 | 青娱视觉盛宴免费国产在线 |