亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯(lián)系我們
日韩精品一区二区三区中文不卡,国产日韩亚洲VA无码自线免费看不卡
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-phospho-PPAR alpha (Ser12)/Cy5 Conjugated antibody (bs-4055R-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-4055R-Cy5
英文名稱 Rabbit Anti-phospho-PPAR alpha (Ser12)/Cy5 Conjugated antibody
中文名稱 Cy5標記的磷酸化α型-過氧化酶活化增生受體抗體
別    名 PPAR alpha (phospho-Ser12); PPAR alpha (phospho-S12); p-PPAR alpha (Ser12); p-PPAR alpha (S12); hPPAR; MGC2237; MGC2452; NR1C1; Nuclear receptor subfamily 1 group C member 1; Peroxisome Proliferator Activated Receptor alpha; PPAR; PPAR alpha; PPARA; OTTHUMP00000197740; OTTHUMP00000197741; Peroxisome proliferator-activated receptor alpha; PPAR-alpha; PPARA_HUMAN; PPARalpha.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產品類型 磷酸化抗體 
研究領域 腫瘤  細胞生物  免疫學  轉錄調節(jié)因子  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, Guinea Pig, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human PPAR alpha around the phosphorylation site of ser12
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Peroxisome proliferators are nongenotoxic carcinogens which are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family, termed Peroxisome Proliferator Activated Receptors (PPARs). Nuclear hormone receptors are ligand dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate ligand. Studies indicate that PPARs are activated by peroxisome proliferators such as clofibric acid, nafenopin, and WY-14,643, as well as by some fatty acids. It has also been shown that PPARs can induce transcription of acyl coenzyme A oxidase and cytochrome P450 A6 (CYP450 A6) through interaction with specific response elements. PPAR alpha is activated by free fatty acids including linoleic, arachidonic, and oleic acids. Induction of peroxisomes by this mechanism leads to a reduction in blood triglyceride levels. PPAR alpha is expressed mainly in skeletal muscle, heart, liver, and kidney and is thought to regulate many genes involved in the beta-oxidation of fatty acids. Activation of rat liver PPAR alpha has been shown to suppress hepatocyte apoptosis. PPAR alpha, like several other nuclear hormone receptors, heterodimerizes with retinoic X receptor (RXR) alpha to form a transcriptionally competent complex.

Function:
Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2.

Subunit:
Heterodimer; with RXRA. This heterodimerization is required for DNA binding and transactivation activity. Interacts with AKAP13, LPIN1 and PRDM16. Also interacts with PPARBP coactivator in vitro. Interacts with CITED2; the interaction stimulates its transcriptional activity (By similarity). Interacts with NCOA3 and NCOA6 coactivators. Interacts with ASXL1 AND ASXL2.

Subcellular Location:
Nucleus.

Tissue Specificity:
Skeletal muscle, liver, heart and kidney.

Similarity:
Belongs to the nuclear hormone receptor family. NR1 subfamily.
Contains 1 nuclear receptor DNA-binding domain.

Database links:

Entrez Gene: 5465 Human

Entrez Gene: 19013 Mouse

Entrez Gene: 25747 Rat

Omim: 170998 Human

SwissProt: Q07869 Human

SwissProt: Q6I9S0 Human

SwissProt: P23204 Mouse

SwissProt: Q542P9 Mouse

SwissProt: P37230 Rat

Unigene: 103110 Human

Unigene: 710044 Human

Unigene: 212789 Mouse

Unigene: 9753 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.a6308.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
国产精品老熟女视频一区二区 | 中出人妻中文字幕无码 | 综合精品欧美日韩在线观看 | 国产成人无码区免费内射一片色欲 | 精品乱码一区二区三区四区 | 国产爱豆果冻传媒在线观看 | A级成人毛片免费视频 | 扒开双腿猛进入爽爽在线观看 | 国产乱妇乱子视频在播放 | 久久久精品国产亚洲AV无码 | 女儿国3在线观看免费版高清 | 夜鲁夜鲁很鲁在线视频视频 | 国产精品久久久久久福利 | 国产精品自在拍在线播放 | 91精品国产乱码久久久久久 | 九热这里只有精品 | 欧美亚洲日本一区二区三区浪人 | **色毛片免费看 | 国产精品中文原创AV巨作首播 | 日韩人妻无码精品-专区 | 最近高清中文字幕无吗免费看 | 日韩字幕在线观看一二三四区 | 91福利国产在线播放午夜 | 亚洲欧洲无卡二区视頻 | 综合人妻久久一区二区精品 | 漂亮人妻被强中文字幕 | 亚洲欧美一区二区三区孕妇写真 | 中文字幕亚洲无线码 | 久久毛片免费看一区二区三区 | 又湿又紧又大又爽又A视频 一二三四社区在线中文视频 | 水蜜桃AV无码专区亚洲AV麻豆 | a色毛片免费视频 | 少妇野外一级内射婬片免费放 | 二区久久久国产AV色 | 天天综合网网欲色 | 黄图男在上女在下 | 免费国产美女爽到喷出水来视频 | 日韩欧美一中文字慕2O22 | 欧美性爱视频免费观看 | 久久亚洲美日韩精品无码一区二区 | avtt天堂网heyzo系列 |