亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
中国女人精69xxxxxx视频 ,性猛交xxxx乱大交孕妇,野花香日本大全免费观看
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-HSPG2/Heparan Sulfate Proteoglycan 2/AP Conjugated antibody (bs-5072R-AP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-5072R-AP
英文名稱 Rabbit Anti-HSPG2/Heparan Sulfate Proteoglycan 2/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的硫酸乙酰肝素蛋白多糖2抗體
別    名 Heparan Sulphate Proteoglycan; Perlecan; Basement membrane specific heparan sulfate proteoglycan core protein; Endorepellin (domain V region); Heparan Sulfate Proteoglycan; Heparan sulfate proteoglycan of basement membrane; HSPG 2; HSPG; Hspg2; LG3 peptide; Perlecan; PLC antibody Schwartz Jampel syndrome 1 (chondrodystrophic myotonia); SJA antibody SJS antibody SJS1 antibody.   
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  免疫學  轉錄調節(jié)因子  糖蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,  (predicted: Mouse, Rat, Pig, Cow, Horse, )
產品應用 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 469kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Heparan Sulfate Proteoglycan 2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes the perlecan protein, which consists of a core protein to which three long chains of glycosaminoglycans(heparan sulfate or chondroitin sulfate) are attached. The perlecan protein is a large multidomain proteoglycan that binds to and cross-links many extracellular matrix components and cell-surface molecules. It has been shown that this protein interacts with laminin, prolargin, collagen type IV, FGFBP1, FBLN2, FGF7 and Transthyretin, etc. and plays essential roles in multiple biological activities. Perlecan is a key component of the vascular extracellular matrix, where it helps to maintain the endothelial barrier function. It is a potent inhibitor of smooth muscle cell proliferation and is thus thought to help maintain vascular homeostasis. It can also promote growth factor (e.g., FGF2) activity and thus stimulate endothelial growth and re-generation. It is a major component of basement membranes, where it is involved in the stabilization of other molecules as well as being involved with glomerular permeability to macromolecules and cell adhesion. Mutations in this gene cause Schwartz-Jampel syndrome type 1, Silverman-Handmaker type of dyssegmental dysplasia, and Tardive dyskinesia.[provided by RefSeq, Mar 2010].

Function:
Integral component of basement membranes. Component of the glomerular basement membrane (GBM), responsible for the fixed negative electrostatic membrane charge, and which provides a barrier which is both size- and charge-selective. It serves as an attachment substrate for cells. Plays essential roles in vascularization. Critical for normal heart development and for regulating the vascular response to injury. Also required for avascular cartilage development.
[FUNCTION] Endorepellin in an anti-angiogenic and anti-tumor peptide that inhibits endothelial cell migration, collagen-induced endothelial tube morphogenesis and blood vessel growth in the chorioallantoic membrane. Blocks endothelial cell adhesion to fibronectin and type I collagen. Anti-tumor agent in neovascularization. Interaction with its ligand, integrin alpha2/beta1, is required for the anti-angiogenic properties. Evokes a reduction in phosphorylation of receptor tyrosine kinases via alpha2/beta1 integrin-mediated activation of the tyrosine phosphatase, PTPN6.

The LG3 peptide has anti-angiogenic properties that require binding of calcium ions for full activity.

Subcellular Location:
Secreted, extracellular space, extracellular matrix, basement membrane.

Tissue Specificity:
Found in the basement membranes.

Post-translational modifications:
Proteolytic processing produces the C-terminal angiogenic peptide, endorepellin. This peptide can be further processed to produce the LG3 peptide.
N- and O-glycosylated; contains three heparan sulfate chains. The LG3 peptide contains at least three and up to five potential O-glycosylation sites but no N-glycosylation.

Similarity:
Contains 4 EGF-like domains.
Contains 22 Ig-like C2-type (immunoglobulin-like) domains.
Contains 11 laminin EGF-like domains.
Contains 3 laminin G-like domains.
Contains 3 laminin IV type A domains.
Contains 4 LDL-receptor class A domains.
Contains 1 SEA domain.

Database links:

Entrez Gene: 444872 Cow

Entrez Gene: 3339 Human

Entrez Gene: 15530 Mouse

Omim: 142461 Human

SwissProt: P98160 Human

SwissProt: Q05793 Mouse

Unigene: 562227 Human

Unigene: 273662 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.a6308.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
高清一区二区三区日本久 | 中文字幕亚洲综合小综合 | 国产亚洲欧美日本一二三本道 | 午夜福利麻豆国产精品 | 91久久精品国产免费一区金莲 | 久久精品黄AA片一区二区三区 | 精品国产aⅴ无码一区二区91 | 精品国产午夜福利精品推荐 | 综合一区二区自拍亚洲 | 国内精品伊人久久久久 | 黄 色 网 站 免 费 涩涩屋 | 欧美性一交一乱一伦A片 | 麻婆豆传媒一区二区三区 | 亚洲国产精品成人AV无码久久综合网 | 99re久久在热线播放最新地址 | 国产又粗又大又爽又免费视频 | 亚洲国产精品一区二区久久hs | 对白脏话肉麻粗话视频 | 奶头好大揉着好爽gif动态 | 久久中文骚妇内射 | 777久久国产精品无码专区 | 国产婬片Av片久久久久久 | 亚洲精品国产A久久久久久 91手机在线视频观看 | 一区国产传媒国产精品 | 日韩丰满少妇无码内射 | 亚洲欧美日韩国产综合五月天 | 国产一区二区免费在线观看 | 精品国产一区二区三区AV性色 | 扒开老师大腿猛进AAA片软件 | 狠狠综合久久AV一区二区三区 | 极品尤物喷水爆白浆呻吟小说 | 日产亚洲一区二区三区 | 久久狠狠亚洲综合色成人18免费网站 | 91免费精品国偷自产在线不卡 | 国产Av人片乱码色午夜 | 国产无吗一区二区三区在线欢 | 亚洲欧美精品一中文字幕 | 亚洲欧美日韩综合在线观看 | 18禁美女黄网站色大片免费看 | 欧美国产综合日韩一区二区 | 好紧好爽好疼的免费视频全集完整版在线播放 |