亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
精品亚洲一区二区三区在线观看,国内精品久久久久久久999下
Rabbit Anti-HSPG2/Heparan Sulfate Proteoglycan 2/PE-Cy3 Conjugated antibody (bs-5072R-PE-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-5072R-PE-Cy3
英文名稱 Rabbit Anti-HSPG2/Heparan Sulfate Proteoglycan 2/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標(biāo)記的硫酸乙酰肝素蛋白多糖2抗體
別    名 Heparan Sulphate Proteoglycan; Perlecan; Basement membrane specific heparan sulfate proteoglycan core protein; Endorepellin (domain V region); Heparan Sulfate Proteoglycan; Heparan sulfate proteoglycan of basement membrane; HSPG 2; HSPG; Hspg2; LG3 peptide; Perlecan; PLC antibody Schwartz Jampel syndrome 1 (chondrodystrophic myotonia); SJA antibody SJS antibody SJS1 antibody.   
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  免疫學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  糖蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,  (predicted: Mouse, Rat, Pig, Cow, Horse, )
產(chǎn)品應(yīng)用 Flow-Cyt=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 469kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Heparan Sulfate Proteoglycan 2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes the perlecan protein, which consists of a core protein to which three long chains of glycosaminoglycans(heparan sulfate or chondroitin sulfate) are attached. The perlecan protein is a large multidomain proteoglycan that binds to and cross-links many extracellular matrix components and cell-surface molecules. It has been shown that this protein interacts with laminin, prolargin, collagen type IV, FGFBP1, FBLN2, FGF7 and Transthyretin, etc. and plays essential roles in multiple biological activities. Perlecan is a key component of the vascular extracellular matrix, where it helps to maintain the endothelial barrier function. It is a potent inhibitor of smooth muscle cell proliferation and is thus thought to help maintain vascular homeostasis. It can also promote growth factor (e.g., FGF2) activity and thus stimulate endothelial growth and re-generation. It is a major component of basement membranes, where it is involved in the stabilization of other molecules as well as being involved with glomerular permeability to macromolecules and cell adhesion. Mutations in this gene cause Schwartz-Jampel syndrome type 1, Silverman-Handmaker type of dyssegmental dysplasia, and Tardive dyskinesia.[provided by RefSeq, Mar 2010].

Function:
Integral component of basement membranes. Component of the glomerular basement membrane (GBM), responsible for the fixed negative electrostatic membrane charge, and which provides a barrier which is both size- and charge-selective. It serves as an attachment substrate for cells. Plays essential roles in vascularization. Critical for normal heart development and for regulating the vascular response to injury. Also required for avascular cartilage development.
[FUNCTION] Endorepellin in an anti-angiogenic and anti-tumor peptide that inhibits endothelial cell migration, collagen-induced endothelial tube morphogenesis and blood vessel growth in the chorioallantoic membrane. Blocks endothelial cell adhesion to fibronectin and type I collagen. Anti-tumor agent in neovascularization. Interaction with its ligand, integrin alpha2/beta1, is required for the anti-angiogenic properties. Evokes a reduction in phosphorylation of receptor tyrosine kinases via alpha2/beta1 integrin-mediated activation of the tyrosine phosphatase, PTPN6.

The LG3 peptide has anti-angiogenic properties that require binding of calcium ions for full activity.

Subcellular Location:
Secreted, extracellular space, extracellular matrix, basement membrane.

Tissue Specificity:
Found in the basement membranes.

Post-translational modifications:
Proteolytic processing produces the C-terminal angiogenic peptide, endorepellin. This peptide can be further processed to produce the LG3 peptide.
N- and O-glycosylated; contains three heparan sulfate chains. The LG3 peptide contains at least three and up to five potential O-glycosylation sites but no N-glycosylation.

Similarity:
Contains 4 EGF-like domains.
Contains 22 Ig-like C2-type (immunoglobulin-like) domains.
Contains 11 laminin EGF-like domains.
Contains 3 laminin G-like domains.
Contains 3 laminin IV type A domains.
Contains 4 LDL-receptor class A domains.
Contains 1 SEA domain.

Database links:

Entrez Gene: 444872 Cow

Entrez Gene: 3339 Human

Entrez Gene: 15530 Mouse

Omim: 142461 Human

SwissProt: P98160 Human

SwissProt: Q05793 Mouse

Unigene: 562227 Human

Unigene: 273662 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
欧美一级a人与一级A片在线观看 | 国产无遮挡成人免费视频网站 | 欧美一级特黄乱妇高清视频 | 亚洲专区无码天堂中文字幕 | 一级毛片免费在线观看网站 | 又硬又粗又大一区二区三区视频 | 俄罗斯一级毛片aaaa | 91精品国自产在线观看 | 99久女女精品视频在线观看 | 久久精品欧美一区二区三区不卡 | 久久人人爽人人爽人人片AV浪潮 | 亚洲欧美一区二区三区久久 | 动漫美女h片黄动漫在线观看 | 国产精品免费露脸视频 | 无人视频在线观看完整版高清视频 | 午夜福利久久久噜久噜久久综合 | 亚洲午夜尤物中文字幕在线 | 国产系列视频二区 | 永久免费一级av毛片网站 | 日本成本人片高清久久免费 | 日本黄色成年人免费观看 | 午夜福利久久久噜久噜久久综合 | 国产欧美日韩综合一区在线播放 | 女网址www女视频 | 亚洲AV一宅男色影视 | 中文字幕无码a级毛片 | 2021年日本中文字幕在线 | 日本爽爽爽爽爽爽在线观看免 | 久久频这里精品99香蕉久网址 | 丝袜情趣在线资源二区 | 久久精品中文骚妇内射AV | 高清欧美性猛交xxxx黑人猛交 | 欧美日韩1卡2卡3卡免费高清中文精品字幕 | 国产高清乱码又大又圆 | 国产久爱青草视频在线观看 | 亚洲欧洲中文日韩AV无码 | 韩国美女精品久久久久久久 | 亚洲欧美一区二区三区四区 | 国产一区二区视频在线观看 | 一本久道久久综合婷婷五月 | A级成人毛片免费视频高清 国产高清japanese国产 |