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Rabbit Anti-Lysozyme/PE-Cy3 Conjugated antibody (bs-0816R-PE-Cy3)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-0816R-PE-Cy3
英文名稱(chēng) Rabbit Anti-Lysozyme/PE-Cy3 Conjugated antibody
中文名稱(chēng) PE-Cy3標(biāo)記的溶菌酶抗體
別    名 1 4 beta n acetylmuramidase c; 14 beta N acetylmuramidase; 14 beta N acetylmuramidase C; EC 3.2.1.17; lysosyme; Lysozyme C; Lysozyme C precursor; Lyz; LZM; Muramidase.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  激酶和磷酸酶  合成與降解  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat,  (predicted: Pig, Cow, Horse, Rabbit, Sheep, Monkey, Cat, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 17kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 Full length native Lysozyme
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Lysozyme catalyzes the hydrolysis of certain mucopolysaccharides of bacterial cell walls. Specifically, it catalyzes the hydrolysis of the bacterial cell wall beta glycosidic linkages between N acetylmuramic acid and N acetylglucosamine. It is found in spleen, lung, kidney, white blood cells, plasma, saliva, milk, and tears.

Subcellular Location:
Secreted.

DISEASE:
Defects in LYZ are a cause of amyloidosis type 8 (AMYL8) [MIM:105200]; also known as systemic non-neuropathic amyloidosis or Ostertag-type amyloidosis. AMYL8 is a hereditary generalized amyloidosis due to deposition of apolipoprotein A1, fibrinogen and lysozyme amyloids. Viscera are particularly affected. There is no involvement of the nervous system. Clinical features include renal amyloidosis resulting in nephrotic syndrome, arterial hypertension, hepatosplenomegaly, cholestasis, petechial skin rash.

Similarity:
Belongs to the glycosyl hydrolase 22 family.

Database links:

Entrez Gene: 4069 Human

Entrez Gene: 17105 Mouse

Entrez Gene: 17110 Mouse

Omim: 153450 Human

SwissProt: P61626 Human

SwissProt: P08905 Mouse

Unigene: 524579 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

溶菌酶(lysozyme )又稱(chēng)細(xì)胞壁質(zhì)酶(muramidase)或n-乙酰胞壁質(zhì)聚糖水解酶(n-acetylmuramideglycanohydralase)。
對(duì)于哺乳動(dòng)物溶菌酶,其牛、豬、貓、兔、猴、馬、羊等動(dòng)物的乳汁中分離出溶菌酶,其化學(xué)性質(zhì)與人溶菌酶相似。
溶菌酶作為機(jī)體非特異免疫因子之一,參與機(jī)體多種免疫反應(yīng),在機(jī)體正常防御功能和非特異免疫中,具有保持機(jī)體生理平衡的重要作用??筛纳坪驮鰪?qiáng)巨嗜細(xì)胞吞噬和消化功能,激活白細(xì)胞吞噬功能,并能改善細(xì)胞抑制劑所導(dǎo)致的白細(xì)胞減少,從而增強(qiáng)機(jī)體的抵抗力。
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