亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
日韩一区二区三区四区区区,欧美精品综合视频一区二区,久久综合色一综合色88
Rabbit Anti-UBE2C/BF647 Conjugated antibody (bs-8357R-BF647)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-8357R-BF647
英文名稱 Rabbit Anti-UBE2C/BF647 Conjugated antibody
中文名稱 BF647標(biāo)記的泛素蛋白連接酶C抗體
別    名 Cyclin selective ubiquitin carrier protein; dJ447F3.2; Mitotic specific ubiquitin conjugating enzyme; UB E2C; UBCH 10; UBCH10; UBE 2C; Ube2c; UBE2C_HUMAN; Ubiquitin carrier protein C; Ubiquitin carrier protein E2 C; Ubiquitin carrier protein E2C; Ubiquitin conjugating enzyme E2 C; Ubiquitin conjugating enzyme E2C; Ubiquitin protein ligase C; Ubiquitin-conjugating enzyme E2 C; Ubiquitin-protein ligase C.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 20kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human UBE2C
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. The first step requires the ATP-dependent activation of the Ub C-terminus and the assembly of multi-Ub chains by the Ub-activating enzyme known as the E1 component. The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex. The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate. UBE2C, also designated UBCH10 in human, is an E2 ubiquitin conjugating enzyme for the anaphase promoting complex (APC), which coordinates mitosis and G1 by sequentially promoting the degradation of key cell-cycle regulators. UBE2C is overexpressed in many different types of cancers and may be a potential therapeutic target.

Function:
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.

Subunit:
Component of the APC/C complex.

Post-translational modifications:
Autoubiquitinated by the APC/C complex, leading to its degradation by the proteasome. Its degradation plays a central role in APC/C regulation, allowing cyclin-A accumulation before S phase entry. APC/C substrates inhibit the autoubiquitination of UBE2C/UBCH10 but not its E2 function, hence APC/C remaining active until its substrates have been destroyed.

Similarity:
Belongs to the ubiquitin-conjugating enzyme family.

Database links:
UniProtKB/Swiss-Prot: O00762.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
亚洲精品123区在线观看 | 伴郎粗大的内捧猛烈进出视频观看 | 丝袜精品人妻自慰喷白浆一区 | 大片免免费观看视频播放网站 | 国产一区二区女内射 | 久久综合亚洲色hezyo国产 | 国产MD视频一区二区三区 | 国产亚洲精品中文带字幕21页 | 中出人妻中文字幕无码 | 中文字幕高清在线免费播放 | 两口子交换真实刺激高潮 | 久久综合色一综合色88 | 久久自慰流水喷白浆免费看 | 久碰人澡人澡人澡人澡91 | 国产午夜精品喷水久久 | 成人区人妻精品一区二区不卡视频 | 18禁黄久久久AAA片 | 国产猛男猛女超爽免费视频 | 打扑克污黄对网站在线看 | 亚洲综合色区另类aV无码 | 欧美一区二区在线观看 | 国产剧情AV不卡在线观看 | yellow片免费观看在线 | 真人插B免费视频播放 | 主人在调教室性调教女仆游戏 | 日本黄页免费视频播放网站 | 亚州一级一片无码内射 | 欧美va亚洲va在线观看不卡 | 热re99久久精品国99热 | 日韩一区二区在线免费观看 | 少妇高潮好爽在线播放 | 最好看的最新的中文字幕1 中文字幕AV在线一二三区 | 综合精品欧美日韩在线观看 | 九九线精品视频在线观看视频 | 大陆精大陆国产国语精品 | 国产福利影院在线观看 | 中文无码AV人妻一级字幕VR | 国产精品一线二线三线 | 重口SM一区二区三区视频 | 亚洲一区二区三区高清AV | 久久久久久黃色網站免費 |