亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯(lián)系我們
欧美日韩中文字幕群交视频在线观看 ,亚洲色欲国产综合久久天堂
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-FBXO11/Gold Conjugated antibody (bs-8472R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-8472R-Gold
英文名稱 Rabbit Anti-FBXO11/Gold Conjugated antibody
中文名稱 膠體金標記的F-box蛋白相關蛋白11抗體
別    名 F box protein 11; F-box only protein 11; FBX11; FBX11_HUMAN; Fbxo11; Fbxo 11; Fbxo-11; PRMT9; VIT-1; VIT1; Vitiligo associated protein VIT 1; Vitiligo-associated protein 1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  免疫學  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Sheep, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 104kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FBXO11
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
This gene encodes a member of the F-box protein familywhich is characterized by an approximately 40 amino acid motif, theF-box. The F-box proteins constitute one of the four subunits ofubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box),which function in phosphorylation-dependent ubiquitination. TheF-box proteins are divided into 3 classes: Fbws containing WD-40domains, Fbls containing leucine-rich repeats, and Fbxs containingeither different protein-protein interaction modules or norecognizable motifs. The protein encoded by this gene belongs tothe Fbxs class. It can function as an arginine methyltransferasethat symmetrically dimethylates arginine residues, and it acts asan adaptor protein to mediate the neddylation of p53, which leadsto the suppression of p53 function. This gene is known to bedown-regulated in melanocytes from patients with vitiligo, a skindisorder that results in depigmentation. Polymorphisms in this geneare associated with chronic otitis media with effusion andrecurrent otitis media (COME/ROM), a hearing loss disorder, and theknockout of the homologous mouse gene results in the deaf mousemutant Jeff (Jf), a single gene model of otitis media.Alternatively spliced transcript variants encoding distinctisoforms have been identified for this gene. [provided by RefSeq,Jun 2010].

Function:
Substrate recognition component of the a(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex whichmediates the ubiquitination and subsequent proteasomal degradationof target proteins. Probably recognizes and binds to phosphorylatedtarget proteins. Binds to and neddylates phosphorylated p53/TP53,inhibiting its transcriptional activity. SCF(FBXO11) does not seemto direct ubiquitination of TP53.

Subunit:
Component of the probable SCF(FBXWO11) complex consisting of CUL1, RBX1, SKP1 and FBXO11. Interacts with TP53.

Subcellular Location:
Nucleus

Tissue Specificity:
Isoform 5 is expressed in keratinocytes, fibroblasts and melanocytes.

Similarity:
Contains 1 F-box domain.
Contains 19 PbH1 repeats.
Contains 1 UBR-type zinc finger.

Database links:

Entrez Gene: 80204 Human

Entrez Gene: 225055 Mouse

Entrez Gene: 301674 Rat

Omim: 607871 Human

SwissProt: Q86XK2 Human

SwissProt: Q7TPD1 Mouse

SwissProt: Q7TSL3 Rat

Unigene: 352677 Human

Unigene: 386857 Mouse

Unigene: 36585 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.a6308.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
亚洲中文久久精品中文字幕 | 最新中文字幕日本 | 97色伦图片97色伦图影院久久 | 欧美大片xxxxbbbb | 亚洲av手机在线观看 | 精品久久久久久精品中文字幕无码 | 国产99精品在线观看 | 中国又粗又大又黄大片 | 真实国产乱人伦在线视频播放 | 豆奶视频在线观看免费高清版 | 一级毛片在线免费播放 | 成 人 黄 色 免费 网站无毒 | 欧美一级a人与一级A片在线观看 | 国产精品无码AV片在线专区 | 女自慰喷潮久久久.www | 久久久av久av久片一区二区 | 美女脱了奶罩看到大乳 | 少妇高潮灌满白浆毛片免费看 | 性成熟黑人双插美国1819 | 蜜桃视频无码区在线观看 | 女人脱精光让人桶爽了 | 国内大量揄拍人妻在线视频 | 茄子在线看片免费人成视频 | 无码AV大香线蕉伊人久久九色 | WWW射我里面在线观看 | 无码成A毛片免费 | 国产女主播喷水视频在线观看 | 99精品人妻无码专区在线视频 | 搡老熟女老女人一区二区三区 | 欧美日韩高清一区 | 日本韩国欧美一区 | 国产无遮挡成人免费视频网站 | 久久免费看少妇级毛片蜜臀 | 美女隐私视频黄www视频 | 中国免费一级毛片 | 三个男人躁我一个爽是什么剧 | 激情内射亚洲一区二区三区爱妻 | …久久精品99久久香蕉国产 | 最近日本字幕MV高清在线观看 | 国产女人高潮叫床男人桶到爽 | 蜜桃TV成人网站免费打开 |