亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯(lián)系我們
国产AV一区二区三区,久久se精品一区精品二区,恩恩呜呜好大好爽快点
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-ZNRF3/PE-Cy3 Conjugated antibody (bs-9141R-PE-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-9141R-PE-Cy3
英文名稱 Rabbit Anti-ZNRF3/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標記的鋅指蛋白3/環(huán)指蛋白3抗體
別    名 Novel C3HC4 type Zinc finger (ring finger); RING finger protein 203; RNF203; Zinc and ring finger 3; Zinc/RING finger protein 3; Znrf3; ZNRF3_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  神經生物學  鋅指蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 95kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZNRF3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). ZNRF3 (Zinc/RING finger protein 3), also known as RNF203 (RING finger protein 203), is a 936 amino acid single pass transmembrane protein that contains one RING-type zinc finger. Related zinc/RING finger proteins, such as ZNRF1 and ZNRF2, are E3 ubiquitin-protein ligases that are thought to be involved in the establishment and maintenance of neuronal transmission and plasticity, therefore it is likely that ZNRF3 may function in a similar manner.

Function:
E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.

Subunit:
Interacts with LRP6, FZD4, FZD5, FZD6 and FZD8. Interacts with RSPO1; interaction promotes indirect interaction with LGR4 and membrane clearance of ZNRF3.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Similarity:
Belongs to the ZNRF3 family.
Contains 1 RING-type zinc finger.

Database links:

Entrez Gene: 84133 Human

Omim: 612062 Human

SwissProt: Q9ULT6 Human

Unigene: 655242 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.a6308.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
爽到高潮无码视频在线观看 | 黑人玩弄极品人妻系列 | 麻豆AV无码精品一区二区 | 国产成人午夜精品免费视频 | 国产精品成人99久久久久 | 日本视频在线免费 | 欧美久久久噜久噜久久XXⅩ交 | 最近高清中文在线字幕在线观看1 | 女性高爱潮AAAA级视频免费 | 亚洲AV无码一区二区二三区 | 丁香花在线影院观看在线播放 | 日韩人欧美?片内射∵久久中国 | 在线视频精品免费观看10 | 男男体育生乱yin高H肉汁 | 人妻少妇精品视频一区二区三区 | 粉嫩国产15xxxxx | 我们日本在线观看免费动漫下载 | 国产2021中文天码字幕 | 亚洲国产高清国产拍精品 | 中文字幕日韩精品无码内射 | 欧美bbbbbxxxxx | 日本夜爽爽一区二区三区 | 中文字幕网伦射乱中文 | 手机在线精品视频 | 插B内射18免费视频 内射无套在线观看高清完整免费 | 精品日韩二区三区精品视频 | 加勒比黑人喝羽月希奶水 | 肉大捧一进一出免费视频 | 亚洲AV无码片一区二区三区 | 在线免费观看日韩视频 | 成年女人免费播放专区 | 欧美bbw极品另类 | 国产麻豆精品久久一二三 | 国产欧美一区二区精品性色 | 亚洲AV成人影视在线观看 | 四虎影库在线永久影院免费观看 | 亚洲精品国产综合久久一线 | 久久精品人妻综合AV | 无码人妻精品一区二区中文 | 一级二级无码电影在线观看 | 精品久久久久中文字幕日本 |