亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
强行内射无码毛片视频,亚洲av手机在线观看,亚洲国产日韩欧美高清片a
Rabbit Anti-ZNRF3/BF488 Conjugated antibody (bs-9141R-BF488)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-9141R-BF488
英文名稱 Rabbit Anti-ZNRF3/BF488 Conjugated antibody
中文名稱 BF488標(biāo)記的鋅指蛋白3/環(huán)指蛋白3抗體
別    名 Novel C3HC4 type Zinc finger (ring finger); RING finger protein 203; RNF203; Zinc and ring finger 3; Zinc/RING finger protein 3; Znrf3; ZNRF3_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  鋅指蛋白  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 95kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZNRF3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). ZNRF3 (Zinc/RING finger protein 3), also known as RNF203 (RING finger protein 203), is a 936 amino acid single pass transmembrane protein that contains one RING-type zinc finger. Related zinc/RING finger proteins, such as ZNRF1 and ZNRF2, are E3 ubiquitin-protein ligases that are thought to be involved in the establishment and maintenance of neuronal transmission and plasticity, therefore it is likely that ZNRF3 may function in a similar manner.

Function:
E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.

Subunit:
Interacts with LRP6, FZD4, FZD5, FZD6 and FZD8. Interacts with RSPO1; interaction promotes indirect interaction with LGR4 and membrane clearance of ZNRF3.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Similarity:
Belongs to the ZNRF3 family.
Contains 1 RING-type zinc finger.

Database links:

Entrez Gene: 84133 Human

Omim: 612062 Human

SwissProt: Q9ULT6 Human

Unigene: 655242 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
亚洲国产精品剧情污污 | 国产h视频在线观看免费 | 久久国产精品自线拍免费 | 美国乱码日产精品BD在线观看 | 日韩网站在线观看 | 太紧了夹得我的巴好爽欧美 | 四虎影视国产精品亚洲精品 | 国产欧美日韩精品视频一区二区三区 | 日韩中亚欧美美日更新 | 国产在线码观看超清无码视频 | 国产精品久久久久久精品爆乳 | 日本人爽p大片免费看 | 久久国产精品自线拍免费 | 欧美日韩无套内射另类 | 国产亚洲成AⅤ人片在线观看 | 717影院理论午夜伦八戒 | 欧美精品综合视频一区二区 | 原神乳液狂飙开襟网站MIMEI | 艳妇乳肉豪妇荡乳AV无码福利 | 内射人妻无码色AB麻豆 | 扒开腿挺进湿润的花苞 | 成人国产在线看不卡 | 国产麻豆成人传媒免费观看 | 久久久久久亚洲av无码专区 | 一级特黄大片欧美久久久久久 | 最近中文字幕在线++中文 | 国产精品国产三级国产AV剧情 | 痉挛大量潮喷精品无码视频 | 国产精品一区二区在线观看99 | 对白脏话肉麻粗话视频 | 综合激情丁香久久狠狠男同 | 欧美高清在线视频一区二区 | 麻豆传播媒体免费版官网 | 加勒比无码人妻一区二区三区 | A国产一区二区免费入口 | 人妻内射一区二区在线视频 | 国产乱熟肥女视频网站 | 久久99久久99精品免视看国产四区 | 中文字幕在线一区二区三区 | 国产一卡 二卡三卡四卡无卡乱码视频 | 国产不卡视频在线播放 |