亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
日韩大片高清播放器大全,伊人久久大香线蕉综合,最近中文字幕完整视频高清1
Rabbit Anti-OAT1 / SLC22A6/BF555 Conjugated antibody (bs-0606R-BF555)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-0606R-BF555
英文名稱 Rabbit Anti-OAT1 / SLC22A6/BF555 Conjugated antibody
中文名稱 BF555標(biāo)記的陰離子轉(zhuǎn)運蛋白-1抗體
別    名 Organic anion transporter 1; OAT1; OAT-1; solute carrier family 22 (organic anion transporter), member 6; FLJ55736; HOAT1; MGC124962; MGC45260; mOat1; NKT; Oat; Orctl1; PAHT; ROAT1; SLC22A6; S22A6_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 轉(zhuǎn)運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 62kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human OCT-1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Recent advances in molecular biology have identified three organic anion transporter families: the organic anion transporter (OAT) family encoded by SLC22A, the organic anion transporting peptide (OATP) family encoded by SLC21A (SLCO), and the multidrug resistance-associated protein (MRP) family encoded by ABCC. These families play critical roles in the transepithelial transport of organic anions in the kidneys as well as in other tissues such as the liver and brain. Among these families, the OAT family plays the central role in renal organic anion transport. Knowledge of these three families at the molecular level, such as substrate selectivity, tissue distribution, and gene localization, is rapidly increasing.

Function:
Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS) (By similarity). Mediates the sodium-independent uptake of p-aminohippurate (PAH), ochratoxin (OTA), acyclovir (ACV), 3'-azido-3-'deoxythymidine (AZT), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), hippurate (HA), indoleacetate (IA), indoxyl sulfate (IS) and 3-carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF), cidofovir, adefovir, 9-(2-phosphonylmethoxyethyl) guanine (PMEG), 9-(2-phosphonylmethoxyethyl) diaminopurine (PMEDAP) and edaravone sulfate. PAH uptake is inhibited by p-chloromercuribenzenesulphonate (PCMBS), diethyl pyrocarbonate (DEPC), sulindac, diclofenac, carprofen, glutarate and okadaic acid (By similarity). PAH uptake is inhibited by benzothiazolylcysteine (BTC), S-chlorotrifluoroethylcysteine (CTFC), cysteine S-conjugates S-dichlorovinylcysteine (DCVC), furosemide, steviol, phorbol 12-myristate 13-acetate (PMA), calcium ionophore A23187, benzylpenicillin, furosemide, indomethacin, bumetamide, losartan, probenecid, phenol red, urate, and alpha-ketoglutarate.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Strongly expressed in kidney and to a lower extent in liver, skeletal muscle, brain and placenta. Found at the basolateral membrane of the proximal tubule.

Post-translational modifications:
Glycosylated. Glycosylation at Asn-113 may occur at a secondary level. Glycosylation is necesssary for proper targeting of the transporter to the plasma membrane.

Similarity:
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

Database links:

Entrez Gene: 9356 Human

Entrez Gene: 18399 Mouse

Entrez Gene: 29509 Rat

Omim: 607582 Human

SwissProt: Q4U2R8 Human

SwissProt: Q8VC69 Mouse

SwissProt: O35956 Rat

Unigene: 369252 Human

Unigene: 30090 Mouse

Unigene: 87849 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

OAT1 陰離子轉(zhuǎn)運蛋白是一類分布廣泛的膜蛋白,通過介導(dǎo)Cl-/HCO-3跨膜轉(zhuǎn)運參與細(xì)胞內(nèi)pH、細(xì)胞體積及細(xì)胞內(nèi)氯離子濃度的調(diào)節(jié)。bs-0607R為抗大、小鼠。
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
欧美日本韩国一二区视频 | 中文字幕无线码免费人妻 | 成人妇女免费播放久久久 | 国产精品k频道在线看 | 亚洲熟妇色自偷自拍另类 | 91麻豆成人精品国产免费网站 | 先峰中文字幕一二三区 | 久久久精品国产亚洲成人满18免费网站 | 公么大龟弄得我好舒服秀婷视频 | 亚欧日韩毛片在线看免费网站 | 最近中文字幕mv免费视频 | 99久久国产精品亚洲综合看片 | 小少妇BBBBBBBBBBBB | 美女被抽插到哭内射视频免费 | 日韩精品久久久肉伦网站 | 成全视频免费高清观看在线 | 日本夜爽爽一区二区三区 | 人妖欧美一区二区三区四区 | 一本大道香蕉久在线播放29 | 久久久91精品国产一区二区 | 一本一道久久a久久综合蜜桃 | 少妇无码太爽了不卡视频在线看 | 午夜福利久久久噜久噜久久综合 | 久久香蕉国产线看观看精品蕉 | 亚洲高清一区二区三区电影 | 成人免费无遮挡无码黄漫视频 | 久久久精品久久久久久久久久久 | 亚洲精品日韩片无码中文字幕 | 四川少扫搡BBW搡BBBB | 亚洲国产精品无码久久久久久曰 | 中文字幕亚洲综合久久菠萝蜜 | 黄色网站在线观看免费 | 18禁美女裸体网站免费扒内衣 | 天天影视色香欲综合网老头 | 伊人久久大香线蕉综合 | 久久婷婷五月综合色丁香 | 女帝被扒开双腿疯狂输出 | 色偷偷亚洲第一综合网 | 免费看撕开奶罩揉吮奶头视频 | 精品乱码一区内射人妻无码 | 最近的中文字幕在线看视频 |