亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
伊人天伊人天天综合网,国产禁忌A级毛片中字内射
Rabbit Anti-Oct4/PE-Cy3 Conjugated antibody (bs-0830R-PE-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-0830R-PE-Cy3
英文名稱 Rabbit Anti-Oct4/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標(biāo)記的胚胎干細(xì)胞關(guān)鍵蛋白抗體
別    名 MGC22487; Oct 3; Oct 4; Oct-3; Oct-4; OCT3; Oct4; Octamer binding protein 3; Octamer-binding protein 3; Octamer binding protein 4; Octamer binding transcription factor 3; Octamer-binding transcription factor 3; Octamer-4; POU domain transcription factor OCT4; OTF3; OTF4; OTF 3; OTF 4; OTF-3; POU class 5 homeobox 1; POU domain, class 5, transcription factor 1; POU domain class 5 transcription factor 1; PO5F1_HUMAN; POU type homeodomain containing DNA binding protein ; POU5F1.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  染色質(zhì)和核信號(hào)  信號(hào)轉(zhuǎn)導(dǎo)  干細(xì)胞  細(xì)胞周期蛋白  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, )
產(chǎn)品應(yīng)用 Flow-Cyt=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 39kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Octamer4
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Expression of the POU-domain transcription factor Octamer-4 (Oct-4) is widely regarded as a hallmark of pluripotent stem cells. The relationship of Oct-4 to pluripotent stem cells is indicated by its tightly restricted expression to undifferentiated pluripotent stem cells. Upon differentiation to somatic lineages, the expression of Oct-4 disappears rapidly. Unlike the majority of pluripotent stem cell markers, the biological role of Oct-4 has been well characterized. Studies performed in mice point to the critical role of Oct-4 in the establishment and/or maintenance of pluripotent stem cells in an uncommitted state.

Function:
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.

Subunit:
Interacts with UBE2I and ZSCAN10. Interacts with PKM2. Interacts with WWP2.

Subcellular Location:
Cytoplasm.Nucleus.Note=Expressed in a diffuse and slightly punctuate pattern.

Tissue Specificity:
Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues.

Post-translational modifications:
Sumoylation enhances the protein stability, DNA binding and transactivation activity. Sumoylation is required for enhanced YES1 expression (By similarity).
Ubiquitinated; undergoes 'Lys-63'-linked polyubiquitination by WWP2 leading to proteasomal degradation (By similarity).
ERK1/2-mediated phosphorylation at Ser-111 promotes nuclear exclusion and proteasomal degradation. Phosphorylation at Thr-235 and Ser-236 decrease DNA-binding and alters ability to activate transcription.

Similarity:
Belongs to the POU transcription factor family. Class-5 subfamily.
Contains 1 homeobox DNA-binding domain.
Contains 1 POU-specific domain.

Database links:

Entrez Gene: 282316 Cow

Entrez Gene: 5460 Human

Entrez Gene: 18999 Mouse

Entrez Gene: 100127461 Pig

Entrez Gene: 294562 Rat

Omim: 164177 Human

SwissProt: O97552 Cow

SwissProt: Q01860 Human

SwissProt: P20263 Mouse

SwissProt: Q9TSV5 Pig

Unigene: 249184 Human

Unigene: 632482 Human

Unigene: 646545 Human

Unigene: 17031 Mouse

Unigene: 161748 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
亚洲一区二区三区免费看 | 天堂tv亚洲tv日本tv不卡 | 看亚洲A级一级毛片,亚洲AV片 | 特黄特色欧美亚洲高清二区 | 91av免费观看 | WWW夜片内射视频日韩精品成人 | 欧美日韩激情无码专区 | 在线无码一区二区三区不卡 | 曰本a级毛片无卡免费视频 自拍偷区亚洲综合第一页欧18 | 中文字幕亚洲无线码 | 加勒比高清无码二区在线三级免费电影dvd | 久久青青草原精品国产软件 | 少妇无码太爽了视频在线播放 | 久久这里只有精品视频6 | 免费看片A级毛片免费看 | 精品21国产成人综合网在线 | 免费一级毛片私人影院a行 99精产国品一二三产 | 国产成人精品电影在线观看 | 亚洲最大的熟女水蜜桃AV网站 | 国产免费伦精品一区二区三区 | 欧美成人免费观看久久 | 久久狠狠色噜噜狠狠狠狠97 | 91九色视频在线观看 | 十八破女处WWW视频 白丝校花 让我C在线观看91 | 最近免费中文字幕大全高清大全1 | 无码A∨高潮抽搐流白浆国产 | 欧美日韩国产无线码一区 | 久久久久久久久久国产精品免费 | 日韩欧美中文字幕一区 | 国产成人精品午夜福利在线播放 | 国产精品天干天干综合网 | 国产全肉乱妇杂乱视频 | 欧美日韩第一区二区三区 | 国产精品白浆无码流出AV动漫 | 国产精品欧美激情第一页 | 日日躁夜夜躁狠狠久久AV | 国产AV一区二区三区 | 久久久久久高清毛片一级黑人免费 | 18岁日韩内射颜射午夜久久成人 | 伦人伦XXX国产对白 人妻精品久久久久中文字幕一冢本 | 欧美bbbbbxxxxx |