亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
国产乱码一二三区精品,一级毛片视频免费观看
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-TLR4/BF555 Conjugated antibody (bs-1021R-BF555)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-1021R-BF555
英文名稱 Rabbit Anti-TLR4/BF555 Conjugated antibody
中文名稱 BF555標記的Toll樣受體4抗體
別    名 TLR4; TLR-4; TLR 4; ARMD10; CD 284; CD284; CD284 antigen; Homolog of Drosophila toll; hTol; Toll (Drosophila) homolog; TOLL; Toll Endotoxin Hyporesponsiveness; Toll like receptor 4; Toll like receptor 4 precursor; TLR4_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 心血管  免疫學  信號轉導  細胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Rat, Cow,  (predicted: Mouse, Dog, Pig, Sheep, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 90kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from rat TLR4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The Toll-like receptor 4 by activating natural immunity, specific immune response involved in the start-up, Toll-like receptor 4 as an important signal transduction transmembrane receptor involved in the toxin-induced inflammation in the pathological process, its mechanisms of control On a growing concern. all regions were either double-stranded or sequenced with an alternatechemistry or covered by high quality data(i.e., phred quality >=30); an attempt was made to resolve all sequencing problems, such as compressions and repeats; all regions were covered by at least one subclone; and the assembly was confirmed by restriction digest, except on the rare occasion of the clone being a YAC. The following abbreviations are used to associate primary accession numbers given in the feature table with their source databases: Em:, EMBL; Sw:, SWISSPROT; Tr:, TREMBL; Wp:, WORMPEP; Information on the WORMPEP database can be found at. TLR-4 plays an important role in microvascular leakage and leukocyte adhesion under the inflammatory condition associated with nonseptic thermal injury.

Function:
Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by Ni(2+). These responses require non-conserved histidines and are, therefore, species-specific.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Highly expressed in placenta, spleen and peripheral blood leukocytes. Detected in monocytes, macrophages, dendritic cells and several types of T-cells.

Post-translational modifications:
N-glycosylated. Glycosylation of Asn-526 and Asn-575 seems to be necessary for the expression of TLR4 on the cell surface and the LPS-response. Likewise, mutants lacking two or more of the other N-glycosylation sites were deficient in interaction with LPS.

DISEASE:
Genetic variation in TLR4 is associated with age-related macular degeneration type 10 (ARMD10) [MIM:611488]. ARMD is a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane.

Similarity:
Belongs to the Toll-like receptor family.
Contains 18 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 TIR domain.

Database links:

Entrez Gene: 7099 Human

Entrez Gene: 21898 Mouse

Entrez Gene: 29260 Rat

SwissProt: O00206 Human

SwissProt: Q9QUK6 Mouse

SwissProt: Q9QX05 Rat

Unigene: 174312 Human

Unigene: 38049 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Toll樣受體4(TLR4)通過激活天然免疫,參與特異性免疫應答的啟動, Toll樣受體4(TLR4)作為一種重要跨膜信號轉導受體參與了內毒素誘發(fā)炎癥反應的病理過程,對其調控機制的研究日益受到關注.
版權所有 2004-2026 www.a6308.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
亚洲人妻少妇av资源网站 | 国产无遮挡色视频免费观看性色 | 色偷偷亚洲第一综合网 | 亚洲国产美女视频 | 大又大又粗又硬又爽少妇毛片 | 国产超碰人人做人人爰 | 成人免费毛片内射美女APP | 国产又粗又大又爽又免费视频 | 免费看美女隐私网站 | a毛片在线看免费观看 | 国产无码高清在线观看 | 国产一级特黄a大片99 | 国产又粗又猛又爽又黄的视频免费软件 | 人人看人人摸人人操637 | 成人免费看WWW网址入口 | 国产日韩中文字幕 | 亚洲午夜尤物中文字幕在线 | 成人片毛片AAA片免费 | 91精品国产制服啪啪无码 | 亚洲成人在线免费观看 | 无码视频AⅤ在线观看 | 国产精品内射婷婷一级二 | 精品福利一区二区三区免费视频 | 一区二区三区国产 | 亚洲另类小说交换 | 精品无码国产污污污在线观看 | ww美色吧com 中日韩免视频上线全都免费 | 人妻美妇疯狂迎合系列视频 | 色欲国产麻豆一精品一AV一免费 | 国产精品亚洲专区在线播放 | 免费一级肉体全黄毛片365看片 | 视频一区二区三区蜜桃麻豆 | 一级毛片免费播放 | 成人国产射精AV在线 | 亚洲国产中文美日韩欧美特级 | 后入白嫩网红内射99XYZ | 青青草99久久精品国产综合 | 国产娱乐凹凸视觉盛宴在线视频 | 国产第一页浮力影院草草 | 日韩精品人妻AV一区二区三区 | 国产精品亚洲专区在线播放 |