亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關于我們  聯(lián)系我們
人妖欧美一区二区三区四区,亚洲第一免费播放区
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-ARHGAP32/RBITC Conjugated antibody (bs-9296R-RBITC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-9296R-RBITC
英文名稱 Rabbit Anti-ARHGAP32/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標記的Rho GTP酶激活蛋白32抗體
別    名 Brain-specific Rho GTPase-activating protein; GAB-associated Cdc42/Rac GTPase-activating protein; GC-GAP; GRIT; GTPase regulator interacting with TrkA; p200RhoGAP; p250GAP; PX-RICS; rac GTPase activating protein; Rho GTPase activating protein 32; Rho GTPase-activating protein 32; Rho-type GTPase-activating protein 32; Rho/Cdc42/Rac GTPase-activating protein RICS; RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling; RICS.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經(jīng)生物學  信號轉(zhuǎn)導  細胞周期蛋白  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, )
產(chǎn)品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 230kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ARHGAP32
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
ARHGAP32 is a neuron-associated GTPase-activating protein that may regulate dendritic spine morphology and strength by modulating Rho GTPase.

Function:
GTPase-activating protein (GAP) promoting GTP hydrolysis on RHOA, CDC42 and RAC1 small GTPases. May be involved in the differentiation of neuronal cells during the formation of neurite extensions. Involved in NMDA receptor activity-dependent actin reorganization in dendritic spines. May mediate cross-talks between Ras- and Rho-regulated signaling pathways in cell growth regulation. Isoform 2 has higher GAP activity (By similarity).

Subunit:
nteracts with NTRK1 (via cytoplasmic domain); the interaction is independent of the phosphorylation state of NTRK1. Interacts with SHC3 (via SH2 domain). Interacts with RASA1 (via SH3 domain); the interaction is necessary for the Ras activation and cell transforming activities of ARHGAP32 (By similarity). Interacts with GAB1 and GAB2. Interacts with CRK and CRKL. Found in a complex with CRKL and BCAR1; upon EGF stimulation BCAR1 may be replaced by EGFR. Interacts with NCK1 (via SH3 domain); NCK1 recruits phosphorylated BCAR1 to the complex. Isoform 2 interacts with FYN; the interaction appears to be dependent on tyrosine phosphorylation of ARHGAP32. Interacts with EGFR; the interaction requires EGF stimulation and is increased by SHC3. Interacts with CDC42; the interaction requires constitutively active CDC42. Interacts with CTNNB1, DLG4, CDH2 and GRIN2B (By similarity).

Subcellular Location:
Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell projection, dendritic spine By similarity. Cytoplasm, cell cortex. Endosome membrane By similarity. Golgi apparatus membrane By similarity. Endoplasmic reticulum membrane By similarity. Membrane.

Tissue Specificity:
Isoform 1 and isoform 2 are highly expressed in brain and testis. Isoform 1 is also expressed in other tissues such as lung, liver and spleen.

Post-translational modifications:
Isoform 2 is phosphorylated on multiple tyrosine residues by FYN. Phosphorylated tyrosine residues undergo dephosphorylation after stimulation of NMDA receptors (By similarity). Phosphorylated in vitro by CaMK2 in the presence of calmodulin and calcium; which inhibits GAP activity (By similarity).

Similarity:
Belongs to the PX domain-containing GAP family.
Contains 1 PX (phox homology) domain.
Contains 1 Rho-GAP domain.
Contains 1 SH3 domain.

Database links:

Entrez Gene: 9743 Human

Omim: 608541 Human

SwissProt: A7KAX9 Human

Unigene: 440379 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
国产女人18毛片水真多1 | 人妻精品久久久久中文字幕一冢本 | 精品成人a v无码内射 | 又大又粗欧美黑人AAAAA片 | 精品国产青草久久久久福利 | 一本一本久久a久久精品66 | 欧洲精品A片一区二区免费 国产乱老熟视频乱老熟女51 | 成人免费毛片内射美女APP | 中文字幕+乱码+中文字幕 | 一级卡片亚洲精品发布 | 91久久精品无码一级毛片 | 性色欲情网站IWWW | 国产二级一片内射视频播放 | 伊人一本到本勒蕉在线 | 久久久精品国产亚州AV水蜜桃 | 囯产精品一品二区三区 | 波多野结衣AV无码久久一区 | 免费A级毛片无码无遮挡内射 | 无码av高清毛片在线看 | 免费在线观看成人电影 | 免费又黄又裸乳的gif动态图 | 胸好大用力深一点 | 九九九免费观看视频 | 91精品国产无码高清 | 精品国产福利一区二区在线 | 男人的好看视频1在线观看 久久国产免费一区二区三区 | 狠狠精品干练久久久无码中文字幕 | 99精品一级欧美片免费播放 | 全肉野战高h含苞欲 | 国产精品视频一区二区猎奇 | 无码高潮喷水AV片在线观看 | 99爱在线精品视频免费观看9 | 人妻少妇看AA片偷人精品视频 | 国产乱码精品一区二区三区四川 | 欧美一级特黄aaaaaa在线看首页 | 最大胆裸体人体牲交666 | 亚洲欧洲日本无在线码天堂 | 一级特黄性色生活片一区二区 | h嗯啊~玉足稚嫩奶娃脚乱女 | 成年网站免费人性视频a站 老司机在线精品视频网站 亚洲色熟女图激情另类图区 | 午夜欧美日韩精品久久久久久 |