亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
午夜亚洲WWW湿好大,久久综合给合久久狠狠狠97色,97精品一区二区视频在线观看
Rabbit Anti-ARHGAP32/Cy7 Conjugated antibody (bs-9296R-Cy7)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-9296R-Cy7
英文名稱 Rabbit Anti-ARHGAP32/Cy7 Conjugated antibody
中文名稱 Cy7標(biāo)記的Rho GTP酶激活蛋白32抗體
別    名 Brain-specific Rho GTPase-activating protein; GAB-associated Cdc42/Rac GTPase-activating protein; GC-GAP; GRIT; GTPase regulator interacting with TrkA; p200RhoGAP; p250GAP; PX-RICS; rac GTPase activating protein; Rho GTPase activating protein 32; Rho GTPase-activating protein 32; Rho-type GTPase-activating protein 32; Rho/Cdc42/Rac GTPase-activating protein RICS; RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling; RICS.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞周期蛋白  G蛋白偶聯(lián)受體  G蛋白信號(hào)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, )
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 230kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ARHGAP32
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
ARHGAP32 is a neuron-associated GTPase-activating protein that may regulate dendritic spine morphology and strength by modulating Rho GTPase.

Function:
GTPase-activating protein (GAP) promoting GTP hydrolysis on RHOA, CDC42 and RAC1 small GTPases. May be involved in the differentiation of neuronal cells during the formation of neurite extensions. Involved in NMDA receptor activity-dependent actin reorganization in dendritic spines. May mediate cross-talks between Ras- and Rho-regulated signaling pathways in cell growth regulation. Isoform 2 has higher GAP activity (By similarity).

Subunit:
nteracts with NTRK1 (via cytoplasmic domain); the interaction is independent of the phosphorylation state of NTRK1. Interacts with SHC3 (via SH2 domain). Interacts with RASA1 (via SH3 domain); the interaction is necessary for the Ras activation and cell transforming activities of ARHGAP32 (By similarity). Interacts with GAB1 and GAB2. Interacts with CRK and CRKL. Found in a complex with CRKL and BCAR1; upon EGF stimulation BCAR1 may be replaced by EGFR. Interacts with NCK1 (via SH3 domain); NCK1 recruits phosphorylated BCAR1 to the complex. Isoform 2 interacts with FYN; the interaction appears to be dependent on tyrosine phosphorylation of ARHGAP32. Interacts with EGFR; the interaction requires EGF stimulation and is increased by SHC3. Interacts with CDC42; the interaction requires constitutively active CDC42. Interacts with CTNNB1, DLG4, CDH2 and GRIN2B (By similarity).

Subcellular Location:
Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell projection, dendritic spine By similarity. Cytoplasm, cell cortex. Endosome membrane By similarity. Golgi apparatus membrane By similarity. Endoplasmic reticulum membrane By similarity. Membrane.

Tissue Specificity:
Isoform 1 and isoform 2 are highly expressed in brain and testis. Isoform 1 is also expressed in other tissues such as lung, liver and spleen.

Post-translational modifications:
Isoform 2 is phosphorylated on multiple tyrosine residues by FYN. Phosphorylated tyrosine residues undergo dephosphorylation after stimulation of NMDA receptors (By similarity). Phosphorylated in vitro by CaMK2 in the presence of calmodulin and calcium; which inhibits GAP activity (By similarity).

Similarity:
Belongs to the PX domain-containing GAP family.
Contains 1 PX (phox homology) domain.
Contains 1 Rho-GAP domain.
Contains 1 SH3 domain.

Database links:

Entrez Gene: 9743 Human

Omim: 608541 Human

SwissProt: A7KAX9 Human

Unigene: 440379 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
漂亮人妻被中出中文字幕色 | 亚洲另类小说交换 | 亚洲熟妇一区二区三区 | 蜜桃视频无码区在线观看 | 国产精品户露AV在线户外直播 | 亚洲春色Av无码专区 | 麻豆一区二区三区蜜桃免费 | 日本成人黄色网址 | 四虎国产精品永久地址入口 | 精人妻无码一区二区三区 | 亚洲欧美码明星卡通重口 | 永久中文字幕免费视频网站 | 无码av中文字幕免费放 | 午夜福利一区二区三区高清视频 | 欧美成人另类精品乱码免费不卡播放 | 爱情岛网站亚洲禁18进入 | 色国产精品一区在线观看 | 欧美日韩免费在线观看 | 国产娱乐凹凸视觉盛宴在线视频 | 亚洲人精品亚洲人成在线 | 久久夜色精品国产噜噜亚洲av | 国产精品视频一区二区三区不卡 | 欧美成人se01短视频在线看 | 日韩人妻无码精品久久a免费 | 欧美亚洲精品中文字幕乱码免费高清 | 亚洲AV无码成人精品区国产 | 女人一级毛片免费观看 | 东北美女野外bbwbbw免费 | 亚洲高清无码在线观看 | 蜜桃视频无码区在线观看 | 91无码人妻精品一区 | 欧美日韩国产免费一区二区三区 | 青青国产成人久久111网站 | 免费看午夜高清性色生活片 | 日韩精品在线观看免费 | 国产免费久久久久久久无码浪潮 | 久久一区二区三区精华液使用方法 | 国产麻豆乱子伦午夜视频观看 | 99久久这里只精品国产免费 | 国产精品色内内在线播放 | 人妻精品久久久久中文字幕一冢本 |