亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
特级毛片内射WWW无码,99精品久久久久久久婷婷
Rabbit Anti-phospho-DOK1(Tyr362)/PE-Cy5.5 Conjugated antibody (bs-5289R-PE-Cy5.5)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-5289R-PE-Cy5.5
英文名稱 Rabbit Anti-phospho-DOK1(Tyr362)/PE-Cy5.5 Conjugated antibody
中文名稱 PE-Cy5.5標(biāo)記的磷酸化D酪氨酸激酶衰減蛋白1抗體
別    名 DOK1 (phospho Y362); DOK1 (phospho Tyr362); p-DOK1 (phospho Y362); docking protein 1 (downstream of tyrosine kinase 1); Docking protein 1 (p62(dok)) (Downstream of tyrosine kinase 1) (pp62).; docking protein 1 62kD (downstream of tyrosine kinase 1); Docking protein 1 62kD; Docking protein 1 62kD; Docking protein 1; DOK 1; DOK1; DOK-1; DOK1_HUMAN; Downstream of tyrosine kinase 1; p62(dok); P62DOK; pp62; pp62.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 腫瘤  心血管  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  G蛋白偶聯(lián)受體  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 62kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human DOK1 around the phosphorylation site of Tyr362
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.

Function:
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.

Subunit:
Interacts with ABL1 (By similarity). Interacts with RasGAP and INPP5D/SHIP1. Interacts directly with phosphorylated ITGB3.

Subcellular Location:
Isoform 1: Cytoplasm. Isoform 3: Cytoplasm, perinuclear region.

Tissue Specificity:
Expressed in pancreas, heart, leukocyte and spleen. Expressed in both resting and activated peripheral blood T-cells.

Post-translational modifications:
Constitutively tyrosine-phosphorylated. Phosphorylated by TEC. Phosphorylated by LYN.
Phosphorylated on tyrosine residues by the insulin receptor kinase. Results in the negative regulation of the insulin signaling pathway.
Isoform 3 contains a N-acetylmethionine at position 1.

Similarity:
Belongs to the DOK family. Type A subfamily.
Contains 1 IRS-type PTB domain.
Contains 1 PH domain.

Database links:

Entrez Gene: 1796 Human

Entrez Gene: 13448 Mouse

Entrez Gene: 312477 Rat

Omim: 602919 Human

SwissProt: Q99704 Human

SwissProt: P97465 Mouse

SwissProt: Q4QQV2 Rat

Unigene: 103854 Human

Unigene: 156 Mouse

Unigene: 117974 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
慢点换个姿势进的好深啊小说 | 精品人妻少妇久久久AV | 国产伦精品一区二区三区免费 | 无套内射极品少妇CHINESE | 岳啊灬啊别停灬啊灬快点视频× | 欧美成人免费观看久久 | 日韩丰满少妇无吗视频激情内射 | 白丝校花扒腿让我c在线观看 | 国产精品久久久久永久免费看 | 快穿之浪荡H啪肉NP文肉BL | 插B内射18免费视频 内射无套在线观看高清完整免费 | 伊人久久大香线蕉AV一区二 | 女子SPA养生XO高清盗摄 | 国产精品国产三级国产AV麻豆 | H女主从小被C到大荤话小说 | 日韩一级精品久久久久 | 啊灬啊灬啊灬快灬高潮了听书 | 中文字幕无线码免费人妻 | 日韩视频高清免费看 | 精品21国产成人综合网在线 | 亚洲无码AV一区二区 | 中文字幕人妻少妇引诱隔壁 | AV午夜午夜快憣免费观看 | 最新国产精品好看的国产精品 | 日本动漫精品一区二区三区 | 强行内射无码毛片视频 | 久久黄无码国内久久精品 | 国产美女流白浆的免费视 | 麻花传媒永久免费版的特色 | 2021年日本中文字幕在线 | 欧美亚洲精品中文字幕乱码免费高清 | 日本产品和韩国产品哪个好99 | 亚洲美女又黄又爽在线观看 | 国产又色又爽又刺激在线观看 | 日本中文字幕乱码免费 | 在线无码一区二区三区不卡 | 亚洲精品国产第一综合99久久 | 毛av毛aⅴ毛aaa正片 | 日日摸日日踫夜夜爽无码 | 99久久国产综合精品麻豆 | 精品无码国产污污污在线观看 |