亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
最近2019年中文字幕视频,亚洲国产AV一区二区三区四区,欧美性猛交aaaaa免费看
Rabbit Anti-phospho-E2F1 (Ser337)/Cy5 Conjugated antibody (bs-5305R-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-5305R-Cy5
英文名稱 Rabbit Anti-phospho-E2F1 (Ser337)/Cy5 Conjugated antibody
中文名稱 Cy5標(biāo)記的磷酸化轉(zhuǎn)錄因子E2F-1抗體
別    名 phospho-E2F1(Ser337); p-E2F1 (phospho-Ser337); E2F1 (phospho S337); E2F 1; E2F transcription factor 1; E2F-1; E2f1 E2F transcription factor 1; KIAA4009; mKIAA4009; OTTHUMP00000030661; PBR 3; PBR3; PRB binding protein E2F 1; PRB-binding protein E2F-1; RBAP 1; RBAP-1; RBAP1; RBBP 3; RBBP-3; RBBP3; RBP 3; RBP3; Retinoblastoma associated protein 1; Retinoblastoma binding protein 3; Retinoblastoma-associated protein 1; Retinoblastoma-binding protein 3; Transcription factor E2F1; E2F1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 腫瘤  免疫學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse,  (predicted: Horse, )
產(chǎn)品應(yīng)用 Flow-Cyt=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 46kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human E2F1 around the phosphorylation site of Ser337
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
E2F's are DNA binding proteins, which associate with negative regulators, such as the retinoblastoma p107 protein, resulting in an altered rate of gene transcription. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. E2F1 is proposed to be involved in several cellular processes that range from tumor suppressor, cell progression and oncogenesis. E2F1 overexpression can also drive cells into apoptosis.

Function:
Transcription activator that binds DNA cooperatively with dp proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F-1 binds preferentially RB1 protein, in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent apoptosis.

Subunit:
Component of the DRTF1/E2F transcription factor complex. Forms heterodimers with DP family members. The E2F-1 complex binds specifically hypophosphorylated retinoblastoma protein RB1. During the cell cycle, RB1 becomes phosphorylated in mid-to-late G1 phase, detaches from the DRTF1/E2F complex, rendering E2F transcriptionally active. Interacts with TRRAP, which probably mediates its interaction with histone acetyltransferase complexes, leading to transcription activation. Binds TOPBP1. Interacts with ARID3A (By similarity). Binds EAPP.

Subcellular Location:
Nucleus.

Post-translational modifications:
Phosphorylated by CDK2 and cyclin A-CDK2 in the S-phase (By similarity).

Similarity:
Belongs to the E2F/DP family.

Database links:

Entrez Gene: 1869 Human

Omim: 189971 Human

SwissProt: Q01094 Human

Unigene: 654393 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

E2F1—屬于調(diào)節(jié)性轉(zhuǎn)錄因子E2F家族。有學(xué)者認(rèn)為:E2F-1既可作為癌基因起作用,又可作為抑癌基因起作用。其不同可能由細(xì)胞中其他生長促進(jìn)或抑制性蛋白質(zhì)水平和(或)活性決定,同時(shí)與細(xì)胞所處環(huán)境及器官特異性有關(guān)。在控制細(xì)胞周期和腫瘤抑制基因蛋白的活性方面起關(guān)鍵作用。
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
亚洲欧美日韩成人在线 | 亚洲天天做日日做天天谢日日欢 | 国产成人精品综合在线观看 | 国产黄色在线网站 | 亚洲无码总合另类中文字幕 | 国产亚洲第一伦理第一区 | 中文字幕熟妇久久久人妻 | 精品亚洲一区二区三区在线观看 | 丰满少妇被猛烈高清播放 | 一级做a爰片久久毛片潮喷妓女免费 | 欧美日韩一区精品高免费专区 | 国产高潮精品呻吟久久∧v无码 | 午夜在线观看视频免费成人 | 99re久久在热线播放最新地址 | 中文字幕人成人乱码亚洲电影 | 亚洲无码在线观看视频 | 欧美VA日韩VA国产VA | 亚洲韩欧美第25集完整版 | 少妇高潮惨叫久久久久久电影 | 成年片色大黄全免费网站观看 | 无码人妻精品中文字幕 | 国产亚洲福利精品一区 | 猛烈的抽插她丰满白嫩 | 91精品久久久久久久久久 | 五月丁香六月综合缴情基地 | 蜜臀色欲AV在线播放国产日韩 | 1000部禁止18勿入无码免费 | 无码射肉在线播放视频 | 中文天堂网在线最新版 | 一级毛片在线免费播放 | 亚洲精品无码不卡在线播HE | 免费AV岛国大片在线观看 | 人善交video欧美 | 18禁美女裸体无遮挡免费观看国产 | 国产精品99国产精品久久 | 两个人看的www视频中文字幕 | 中文字幕无码人妻AAA片 | 少妇自慰白浆一区二区 | 国产在线精品一区二区在线看 | 五十路熟妇无码AV在线 | 国产精品看高国产精品不卡 |