亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
91精品国产综合久久福利,粉色视频午夜网站入口,无套内射在线无码播放
Rabbit Anti-phospho-ERK5 ( Ser731+Thr733)/Cy5.5 Conjugated antibody (bs-5486R-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-5486R-Cy5.5
英文名稱 Rabbit Anti-phospho-ERK5 ( Ser731+Thr733)/Cy5.5 Conjugated antibody
中文名稱 Cy5.5標(biāo)記的磷酸化細胞外信號調(diào)節(jié)激酶5抗體
別    名 ERK5 (phospho Ser731 + Thr733); Big MAP kinase 1; BMK 1; BMK 1 kinase; BMK-1; BMK1; BMK1 Kinase; EC 2.7.11.24; ERK 4; ERK 5; ERK-5; ERK4; Extracellular Signal Regulated Kinase 5; Extracellular signal-regulated kinase 5; MAP kinase 7; MAPK 7; MAPK7; Mitogen Activated Protein Kinase 7; Mitogen-activated protein kinase 7; MK07_HUMAN; OTTHUMP00000065906; OTTHUMP00000065907; PRKM 7; PRKM7; PROTEIN KINASE, MITOGEN-ACTIVATED, 7.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 腫瘤  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Cow, Rabbit, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 90kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human ERK5 around the phosphorylation site of Ser731+Thr733
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Function:
Plays a role in various cellular processes such as proliferation, differentiation and cell survival. The upstream activator of MAPK7 is the MAPK kinase MAP2K5. Upon activation, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C. EGF activates MAPK7 through a Ras-independent and MAP2K5-dependent pathway. May have a role in muscle cell differentiation. May be important for endothelial function and maintenance of blood vessel integrity. MAP2K5 and MAPK7 interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. Phosphorylates SGK1 at Ser-78 and this is required for growth factor-induced cell cycle progression.

Subunit:
Interacts with MAP2K5. Forms oligomers. Interacts with MEF2A, MEF2C and MEF2D; the interaction phosphorylates the MEF2s and enhances transcriptional activity of MEF2A, MEF2C but not MEF2D. Interacts with SGK1.

Subcellular Location:
Cytoplasm. Nucleus. Note=Translocates to the nucleus upon activation.

Tissue Specificity:
Expressed in many adult tissues. Abundant in heart, placenta, lung, kidney and skeletal muscle. Not detectable in liver.

Post-translational modifications:
Dually phosphorylated on Thr-219 and Tyr-221, which activates the enzyme. Autophosphorylated in vitro on threonine and tyrosine residues when the C-terminal part of the kinase, which could have a regulatory role, is absent.

Similarity:
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Contains 1 protein kinase domain.

Database links:

Entrez Gene: 5598 Human

Entrez Gene: 23939 Mouse

Entrez Gene: 114509 Rat

Omim: 602521 Human

SwissProt: Q13164 Human

SwissProt: Q9WVS8 Mouse

SwissProt: P0C865 Rat

Unigene: 150136 Human

Unigene: 38172 Mouse

Unigene: 144629 Rat

 



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
99热成人精品国产免男男 | 国产69精品久久久久无码小说 | 久久久精品天堂无码中文字幕 | 麻豆国产AV尤物网站尤物 | 国产午夜亚洲精品国产 | 内射丰满高大五十五岁熟女 | 亚洲欧洲自拍偷拍 | 日本夜爽爽一区二区三区 | 免费的人成黄网站在线观看视频 | 伊人狠狠丁香婷婷综合尤物 | 少妇人妻偷人精品无码视频新浪 | 国产一级特黄aa毛片 | 国产嫖妓一区二区三区无码 | 波多野结衣av一区二区全免费观看 | 国产一级 级内射视频 | 精品一区二区三区高清免费观看 | 欧美日韩激情综合一区二区不卡 | 日本韩国的免费观看视频 | 美女裸体动态图片 | 激情男女高潮射精AV免费 | 亚洲精品免费视频观看视频 | 日韩欧美一区二区三区免费看 | 亚洲精品乱码久久久久66国产成 | 可以在线看av的网站 | av高清无码网址大全 | 一级a性色生活片久久毛片 日韩欧美一中文字慕2O22 | 无码中文字幕拍偷乱偷精品 | 蜜桃视频无码区在线观看 | 91精品国产高清一区二区三蜜臀 | 啊…嗯啊好深男男腐文多人 | 狠狠色噜噜狠狠狠777 | 顶级美妇紧窄湿润御女小说 | 国产一级aa无码大片在线视频 | 午夜夫妻试看120国产 | 精品国产一区二区av麻豆 | 18禁强伦姧人妻又大又久久 | 欧美精品在线观看 | 最近中文字幕2018免费版2019 | 水野优香vagu224在线播放 | 又大又紧又粗C死你视频 | 久久精品视频免费 |