亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
欧美精品久久久久久久小说,国产精品亚洲综合一区在线观看,天天躁日日躁狠狠躁AV麻豆
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-phospho-ERK5 ( Ser731+Thr733)/BF594 Conjugated antibody (bs-5486R-BF594)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-5486R-BF594
英文名稱 Rabbit Anti-phospho-ERK5 ( Ser731+Thr733)/BF594 Conjugated antibody
中文名稱 BF594標記的磷酸化細胞外信號調節(jié)激酶5抗體
別    名 ERK5 (phospho Ser731 + Thr733); Big MAP kinase 1; BMK 1; BMK 1 kinase; BMK-1; BMK1; BMK1 Kinase; EC 2.7.11.24; ERK 4; ERK 5; ERK-5; ERK4; Extracellular Signal Regulated Kinase 5; Extracellular signal-regulated kinase 5; MAP kinase 7; MAPK 7; MAPK7; Mitogen Activated Protein Kinase 7; Mitogen-activated protein kinase 7; MK07_HUMAN; OTTHUMP00000065906; OTTHUMP00000065907; PRKM 7; PRKM7; PROTEIN KINASE, MITOGEN-ACTIVATED, 7.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產品類型 磷酸化抗體 
研究領域 腫瘤  免疫學  信號轉導  轉錄調節(jié)因子  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Cow, Rabbit, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 90kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human ERK5 around the phosphorylation site of Ser731+Thr733
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Function:
Plays a role in various cellular processes such as proliferation, differentiation and cell survival. The upstream activator of MAPK7 is the MAPK kinase MAP2K5. Upon activation, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C. EGF activates MAPK7 through a Ras-independent and MAP2K5-dependent pathway. May have a role in muscle cell differentiation. May be important for endothelial function and maintenance of blood vessel integrity. MAP2K5 and MAPK7 interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. Phosphorylates SGK1 at Ser-78 and this is required for growth factor-induced cell cycle progression.

Subunit:
Interacts with MAP2K5. Forms oligomers. Interacts with MEF2A, MEF2C and MEF2D; the interaction phosphorylates the MEF2s and enhances transcriptional activity of MEF2A, MEF2C but not MEF2D. Interacts with SGK1.

Subcellular Location:
Cytoplasm. Nucleus. Note=Translocates to the nucleus upon activation.

Tissue Specificity:
Expressed in many adult tissues. Abundant in heart, placenta, lung, kidney and skeletal muscle. Not detectable in liver.

Post-translational modifications:
Dually phosphorylated on Thr-219 and Tyr-221, which activates the enzyme. Autophosphorylated in vitro on threonine and tyrosine residues when the C-terminal part of the kinase, which could have a regulatory role, is absent.

Similarity:
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Contains 1 protein kinase domain.

Database links:

Entrez Gene: 5598 Human

Entrez Gene: 23939 Mouse

Entrez Gene: 114509 Rat

Omim: 602521 Human

SwissProt: Q13164 Human

SwissProt: Q9WVS8 Mouse

SwissProt: P0C865 Rat

Unigene: 150136 Human

Unigene: 38172 Mouse

Unigene: 144629 Rat

 



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.a6308.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
国产又滑又嫩又白 | 国产成人AV一区二区三区无码 | 国产又爽又黄无码无遮挡在线观点 | 久久午夜夜伦鲁鲁片不卡 | 久久99国产精品一区二区 | 久久综合九色综合欧美就去吻 | 欧美精品综合视频一区二区 | 91久久综合精品国产丝袜长腿 | 久久久久久91香蕉国产 | 国产高潮精品呻吟久久∧v无码 | 偷拍激情视频一区二区三区 | 国产日韩中文字幕 | 未满十八岁勿入网站WWW | 欧美2021精品AⅤ| YW193.CAN尤物国产在线网页 | 91精品国产无码高清 | 午夜性色一区二区三区不卡视频 | 日韩一进一出免费试频 | 老熟女太熟了A91V | 欧美日本韩国一二区视频 | 久久精品国产亚洲AV热一区 | 人人妻人人爽人人澡欧美二区 | 免费在线看一级黄色网站 | 蜜芽192.MON牢记永不失联 | 中文字幕日韩欧美一区二区三区 | 1000部禁止18勿入无码免费 | 波多野结衣AV在线播放 | 欧美日韩免费播放一区二区 | 最新国产精品自在自线发布 | 免费视频片在线观看大片 | 人妻少妇精品视频一区二区三区 | 亚洲人成网站18禁止久久影院 | 亚洲爆乳无码精品AAA片蜜桃 | 久久久精品日韩免费观看 | 免费无毒A网站在线观看 | 欧美老汉色老汉首页a亚洲 国产精品密蕾丝视频下载 久久精品亚洲精品无码 | 国产一级 级内射视频 | 青草国产精品久久久久久 | 无码免费婬AV片在线观看 | A级黄片人人插人人摸 | 日韩欧美一区二区三区免费观看 |