亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢(xún)技術(shù)支持           掃碼咨詢(xún)技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国产下药迷倒白嫩丰满美女BD,免费无码专区毛片高潮喷水
Rabbit Anti-VAV1/PE-Cy3 Conjugated antibody (bs-4167R-PE-Cy3)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-4167R-PE-Cy3
英文名稱(chēng) Rabbit Anti-VAV1/PE-Cy3 Conjugated antibody
中文名稱(chēng) PE-Cy3標(biāo)記的鳥(niǎo)苷酸轉(zhuǎn)換因子VAV1抗體
別    名 Oncogene vav; p95Vav; Protooncogene vav; Proto-oncogene vav; VAV 1; VAV 1 oncogene; VAV; Vav proto oncogene; Vav proto-oncogene; VAV_HUMAN; VAV1.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  免疫學(xué)  染色質(zhì)和核信號(hào)  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  G蛋白偶聯(lián)受體  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human,  (predicted: Mouse, Rat, Pig, Cow, Horse, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 98kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human VAV1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012].

Function:
Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.

Subunit:
May interact with CCPG1. Interacts with APS, DOCK2, GRB2, GRB3, DOCK2, SLA, TEC and ZNF655/VIK. Interacts with SIAH2; without leading to its degradation. Associates with BLNK, PLCG1, GRB2 and NCK1 in a B-cell antigen receptor-dependent fashion. Interacts with CBLB; which inhibits tyrosine phosphorylation and down-regulates activity. Interacts with SHB and CLNK. Interacts with THEMIS2. Interacts with HCK. Interacts with NEK3 and this interaction is prolactin-dependent. Interacts with ITK. Interacts with PTK2B/PYK2. Interacts (via SH2 domain) with SYK. Interacts with ANKRD54.

Tissue Specificity:
Widely expressed in hematopoietic cells but not in other cell types.

Post-translational modifications:
Phosphorylated on tyrosine residues by HCK in response to IFNG and bacterial lipopolysaccharide (LPS). Phosphorylated by FYN.

Similarity:
Contains 1 CH (calponin-homology) domain.
Contains 1 DH (DBL-homology) domain.
Contains 1 PH domain.
Contains 1 phorbol-ester/DAG-type zinc finger.
Contains 1 SH2 domain.
Contains 2 SH3 domains.

Database links:

Entrez Gene: 7409 Human

Entrez Gene: 22324 Mouse

Entrez Gene: 25156 Rat

Omim: 164875 Human

SwissProt: P15498 Human

SwissProt: P27870 Mouse

SwissProt: P54100 Rat

Unigene: 116237 Human

Unigene: 248172 Mouse

Unigene: 48861 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Vav1蛋白是特異于造血細(xì)胞表達(dá)的鳥(niǎo)苷酸轉(zhuǎn)換因子,它參與了多種免疫細(xì)胞如T細(xì)胞,B細(xì)胞,巨噬細(xì)胞,自然殺傷性細(xì)胞等的胞內(nèi)信號(hào)轉(zhuǎn)導(dǎo),發(fā)揮著重要作用. Vav1主要參與T細(xì)胞信號(hào)傳導(dǎo)途徑,傳導(dǎo)信號(hào)激活鈣流、細(xì)胞外信號(hào)調(diào)節(jié)激酶(ERK)以及轉(zhuǎn)錄因子NFκB。Vav1蛋白在T細(xì)胞生長(zhǎng)發(fā)育、成熟T細(xì)胞激活、細(xì)胞因子合成及細(xì)胞骨架活動(dòng)中發(fā)揮重要作用。
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
推油少妇久久99久久99久久 | 中文字幕久久久久久久免费 | 狠狠躁夜夜躁人人爽天天69 | 久久婷婷五月国产色综合 | 一级特黄特色的免费大片视频 | 国产一区二区精品久久岳√久久 | 加勒比黑人喝羽月希奶水 | 欧美日韩国产色综合一二三四 | 亚洲乱码精品久久久久.. | 四虎国产精品永久地址入口 | 欧美自拍嘿咻内射在线观看 | 中国老少配BBwBBwBBW | 国产放荡AV剧情演绎麻豆 | 日本韩国的免费观看视频 | 成年网站免费视频A在线双飞 | 性色爽爱性色爽爱网站 | 亚洲精品无码av中文字幕网站 | 国产一区二区无码蜜芽精品 | 中文字幕日韩欧美一区二区三区 | 久久久久亚洲AV成人人电影 | 天天躁日日躁狠狠躁AV麻豆 | 欧美不卡视频一区发布 | 天堂8在线天堂资源BT | 色狠台湾色综合网站 | 被两个两个黑人吃奶4P | 国产720刺激在线视频 | 手机在线毛片免费播放 | 国产精品VA在线播放 | 在线观看特色大片免费视频 | 欧美两性人xxxx高清免费 | 精品国产乱码久久久久久蜜桃网站 | 好涩啊揉爆骚奶的视频 | 性奴抽插乳中出精没射视频搜索 | 欧美mv日韩mv国产mv | 在线观看中文最近最新观看 | 精品久久久久久无码人妻热蜜芽 | 国产精品老熟女视频一区二区 | 人妻少妇被猛烈进入中文字幕 | 亚洲国产精品人人爽夜夜爽 | 婷婷久久综合九色综合伊人色 | 精品无码无人网站免费视频 |