亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質(zhì)量反饋  關于我們  聯(lián)系我們
欧美国产综合日韩一区二区,欧美人与拘牲交大全O人禾
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-TRIM25/AP Conjugated antibody (bs-4170R-AP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-4170R-AP
英文名稱 Rabbit Anti-TRIM25/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的雌激素反應鋅指蛋白抗體
別    名 EFP; Estrogen responsive finger protein; RNF 147; RNF147; TRI25; TRIM 25; Tripartite motif containing 25; Tripartite motif containing protein 25; Z147; Zinc finger protein 147; Zinc finger protein 147 (estrogen responsive finger protein); ZNF 147; ZNF147; TRI25_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  免疫學  發(fā)育生物學  染色質(zhì)和核信號  鋅指蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Cow, Sheep, )
產(chǎn)品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 71kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRIM25
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains, a RING, a B box type 1 and a B box type 2, and a coiled coil region. The protein localizes to the cytoplasm. The presence of potential DNA binding and dimerization transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.

Function:
Functions as an ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs.

Subunit:
Interacts (via SPRY domain) with DDX58 (via CARD domain). Interacts (via coiled coil) with influenza A virus NS1 protein; this interaction specifically inhibits TRIM25 multimerization and TRIM25-mediated DDX58 CARD ubiquitination, thereby suppressing DDX58 signal transduction.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Ubiquitous.

Post-translational modifications:
Auto-ISGylated.

Similarity:
Contains 1 B30.2/SPRY domain.
Contains 1 RING-type zinc finger.

Database links:
UniProtKB/Swiss-Prot: Q14258.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.a6308.cn 北京博奧森生物技術有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
日韩美女在线视频一区不卡 | 久久久久久精品毛片A级按摩 | 又大又粗又爽的少妇免费视频 | 女的被弄到高潮娇喘喷水视频 | 亚洲AV无码精品国产天堂-百度 | 亚洲精品1卡2卡三卡23卡 | 国产精品毛片久久久久久久 | 国产精品日韩欧美一区二区三区 | 欧美最猛黑人XXXXWWW | 特黄特色欧美亚洲高清二区 | 欧美性生恔XXXXXDDDD | 国产欧美久久久久久精品一区二区 | 亚洲欧洲中文日韩久久AV乱码 | 伊人福利视频导航 | 欧美日韩精品一区二区在线播放蜜臀 | 中文字幕一区二区人妻性色 | 视频一区在线免费观看 | 中文字幕无码家庭乱欲 | 亚洲成人av综合久久久蜜桃臀 | 亚洲午夜尤物中文字幕在线 | 91精品国产综合久久久久久 | 亚州**色毛片免费观看 | 国产AV无码一二三区天堂 | 国产熟女真实乱精品91 | 国产一级特黄a大片99 | 国产一级无码Av片在线观看 | 亚洲av成人精品一区二区三区 | 中文字幕日韩一区二区不卡 | 粉色视频午夜网站入口 | …久久精品99久久香蕉国产 | 日韩高清免费视频观看 | 亚洲日韩久久精品无码AV | 欧美日韩一区二区三区四区 | 美女被C污黄网站免费观看 又粗又硬女人免费视频 | 国产精品小仙女思妍肉丝 | 99人中文字幕亚洲区三 | 九九精品视频在线观看 | 日韩经典午夜福利发布 | 性短视频在线观看免费不卡流畅 | 日本一级A片在线观看播放 久久精品中文字幕第一页国产精品 | 狂躁美女BBBBBB视频 |