亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
熟妇高潮一区二区在线播放,国产福利一区二区三区在线观看
Rabbit Anti-TRIM25/Cy3 Conjugated antibody (bs-4170R-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-4170R-Cy3
英文名稱 Rabbit Anti-TRIM25/Cy3 Conjugated antibody
中文名稱 Cy3標(biāo)記的雌激素反應(yīng)鋅指蛋白抗體
別    名 EFP; Estrogen responsive finger protein; RNF 147; RNF147; TRI25; TRIM 25; Tripartite motif containing 25; Tripartite motif containing protein 25; Z147; Zinc finger protein 147; Zinc finger protein 147 (estrogen responsive finger protein); ZNF 147; ZNF147; TRI25_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  免疫學(xué)  發(fā)育生物學(xué)  染色質(zhì)和核信號  鋅指蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Cow, Sheep, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 71kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRIM25
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains, a RING, a B box type 1 and a B box type 2, and a coiled coil region. The protein localizes to the cytoplasm. The presence of potential DNA binding and dimerization transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.

Function:
Functions as an ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs.

Subunit:
Interacts (via SPRY domain) with DDX58 (via CARD domain). Interacts (via coiled coil) with influenza A virus NS1 protein; this interaction specifically inhibits TRIM25 multimerization and TRIM25-mediated DDX58 CARD ubiquitination, thereby suppressing DDX58 signal transduction.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Ubiquitous.

Post-translational modifications:
Auto-ISGylated.

Similarity:
Contains 1 B30.2/SPRY domain.
Contains 1 RING-type zinc finger.

Database links:
UniProtKB/Swiss-Prot: Q14258.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
国内精品尹人香蕉综合在线观看 | 欧美日韩高清一区 | 人妻妺妺窝人体色WWW聚色窝 | 一级毛片在线播放观看 | 亚洲AV无码专区在线观看在线 | 亚日韩一二三区视频免费看 | 国产乱码精品一区二区三区四川 | 97亚洲熟妇自偷自拍另类图片 | 国产又爽又黄无码无遮挡在线观看 | 男女无遮挡XX00动态图120秒 | 亚洲纯肉av无码动漫 | 日本高清视频一区二区 | 最近免费中文字幕大全高清MV | 神马免费午夜福利剧场 | 国产不卡视频在线观看 | 综合一区无套内射中文字幕 | 一本到无码高清手机字幕在线播放 | 黄色毛片免费网站 | 男人的天堂无码Av色偷偷 | 精品久久久久久无码不卡 | 国产JLZZJLZZ视频免费看 | 免费观看黄色毛片 | 一本一道久久a久久综合蜜桃 | 老师好大好深好烫撑满了h 亚洲精品综合第一国产综合 | 久久久久久高清毛片一级 | 亚洲字幕AV一区二区三区四区 | 欧美日韩成人VA精品一区二区三区不卡 | 人妻人人澡人人爽人人精品 | 亚洲日本一区二区一本一道 | 精品国产天堂综合一区在线 | 无码区国产区在线播放 | 国产成人手机高清在线观看网站 | 神马免费午夜福利剧场 | 女人赤裸裸正面下身照片 | 亚洲成AV人片一区二区三区 | 伊人婷婷六月狠狠狠去 | 免费看日产一区二区三区 | 中文字幕无码乱码人妻系列 | √天堂中文www官网在线 | 国产乱子伦精品无码码专区 | 亚洲大片在线观看 |