亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
日本不卡高字幕在线2019,久久久久亚洲AV成人人电影,未满十八18禁止免费无码网站
Rabbit Anti-TRIM25/PE-Cy5 Conjugated antibody (bs-4170R-PE-Cy5)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-4170R-PE-Cy5
英文名稱 Rabbit Anti-TRIM25/PE-Cy5 Conjugated antibody
中文名稱 PE-Cy5標(biāo)記的雌激素反應(yīng)鋅指蛋白抗體
別    名 EFP; Estrogen responsive finger protein; RNF 147; RNF147; TRI25; TRIM 25; Tripartite motif containing 25; Tripartite motif containing protein 25; Z147; Zinc finger protein 147; Zinc finger protein 147 (estrogen responsive finger protein); ZNF 147; ZNF147; TRI25_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  免疫學(xué)  發(fā)育生物學(xué)  染色質(zhì)和核信號(hào)  鋅指蛋白  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Cow, Sheep, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 71kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRIM25
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains, a RING, a B box type 1 and a B box type 2, and a coiled coil region. The protein localizes to the cytoplasm. The presence of potential DNA binding and dimerization transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.

Function:
Functions as an ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs.

Subunit:
Interacts (via SPRY domain) with DDX58 (via CARD domain). Interacts (via coiled coil) with influenza A virus NS1 protein; this interaction specifically inhibits TRIM25 multimerization and TRIM25-mediated DDX58 CARD ubiquitination, thereby suppressing DDX58 signal transduction.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Ubiquitous.

Post-translational modifications:
Auto-ISGylated.

Similarity:
Contains 1 B30.2/SPRY domain.
Contains 1 RING-type zinc finger.

Database links:
UniProtKB/Swiss-Prot: Q14258.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
视频一区二区三区蜜桃麻豆 | h嗯啊~玉足稚嫩奶娃脚乱女 | 国产精品自产拍在线观看中文 | 一区二区三区在线播放 | 欧美日韩国产无线码一区 | 国产在线视频欧美一区二区三区 | 精品无码国产AV一区二区性色 | 中文字幕精品亚洲一区 | 久久狠狠亚洲综合色成人18免费网站 | 国产乱子经典视频在线观看 | 欧美日韩一区精品视频一区二区 | 色综合99久久久无码国产精品 | 成人乱码一区二区三区四区 | 亚洲欧美日韩中文久久 | 国产婬片Av片久久久久久 | 国产亚洲日韩在线播放人成 | 一本—道久久a久久精品蜜桃 | 国产变态拳头交视频免费播放 | 美一女一无一伦一精一品 | 日本最新免费的一区二区 | 欧美激情一区二区三区蜜桃视频 | 欧美激情视频一区二区三区免费 | 欧亚成年男女深夜百度网盘 | 亚洲精品动漫免费二区 | 国产免费无码XXXXX视频 | a无码亚洲男人的天堂 | 亚洲人成网站18禁止久久影院 | 亚洲美女又黄又爽在线观看 | 欧美制服丝袜国产日韩一区 | 久久久久久91香蕉国产 | 欧美A∨一区二区三区久久黄 | 欧美极品欧美精品欧美视频 | 亚洲欧美日韩在线精品一区 | 人妻仑乱A级毛片免费看 | 五月天婷五月天综合网 | 亚州**色毛片免费观看 | √天堂中文在线最新版 | 成人网站在线进入爽爽爽 | 午夜精品久久久久久不卡AV | 久久久久亚洲精品天堂久久久久久 | 免费午夜扒丝袜www在线看 |