亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
欧美日韩国产综合草草,国产精品综合日韩精品第一页
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-TRIM25/APC Conjugated antibody (bs-4170R-APC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-4170R-APC
英文名稱 Rabbit Anti-TRIM25/APC Conjugated antibody
中文名稱 APC標記的雌激素反應鋅指蛋白抗體
別    名 EFP; Estrogen responsive finger protein; RNF 147; RNF147; TRI25; TRIM 25; Tripartite motif containing 25; Tripartite motif containing protein 25; Z147; Zinc finger protein 147; Zinc finger protein 147 (estrogen responsive finger protein); ZNF 147; ZNF147; TRI25_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  免疫學  發(fā)育生物學  染色質和核信號  鋅指蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Cow, Sheep, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 71kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRIM25
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains, a RING, a B box type 1 and a B box type 2, and a coiled coil region. The protein localizes to the cytoplasm. The presence of potential DNA binding and dimerization transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.

Function:
Functions as an ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs.

Subunit:
Interacts (via SPRY domain) with DDX58 (via CARD domain). Interacts (via coiled coil) with influenza A virus NS1 protein; this interaction specifically inhibits TRIM25 multimerization and TRIM25-mediated DDX58 CARD ubiquitination, thereby suppressing DDX58 signal transduction.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Ubiquitous.

Post-translational modifications:
Auto-ISGylated.

Similarity:
Contains 1 B30.2/SPRY domain.
Contains 1 RING-type zinc finger.

Database links:
UniProtKB/Swiss-Prot: Q14258.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.a6308.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
欧美又大粗又爽又黄大片视频 | 久久精品国产9久久综合 | 日本三级电影在线看 | 久99久热只有精品国产女同 | 欧美特黄特黄免费三级视频 | 一本AV高清一区二区三区 | 国产精品成人免费久久黄AV片 | 亚洲中文字幕无码中文字 | 最近中文字幕高清字幕mv | 开心婷婷五月综合基地 | 国产精品青青青高清在线 | 一级做a爰片久久毛片潮喷妓女免费 | 日本花心黑人hd捆绑 | 国产成+人+综合+亚洲专 | 中文字幕+乱码+中文乱码www | 99爱在线精品视频网站 | 国产精品无码无卡A级毛片 国产午夜精品理论片小yo奈 | 短篇公交车高H肉辣全集目录 | 综合欧美亚洲首页在线播放 | 嗯好湿用力的啊c进来动态图 | 亚洲AV无码片一区二区三区 | 久久亚洲精品中文字幕 | 国产又爽又黄无码无遮挡在线观点 | 久久天天躁狠狠躁夜夜躁2014 | 久久综合给合久久狠狠狠97色 | 嫦娥仙子含精肉臀迎合 | 人妻少妇精品视频一区97精品 | 无码免费婬AV片在线观看 | 一区二区视频在线观看高清视频在线 | 99精品无人区乱码1区2区3区 | 国产精品后入内射日本在线观看 | 精品国语对白清晰在线 | 飘雪影视在线观看免费观看西瓜 | 一级成人欧美一区在线观看 | 国产精品久久久久无码AV | 欧美人妻少妇精品视频专区 | 久久婷婷国产剧情内射白浆 | 国产午夜亚洲精品区 | 成全视频在线观看免费高清版 | 国产99视频精品免视看7 | 国产精品美女免费视频观看 |