亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯(lián)系我們
国产普通话刺激视频在线播放,一级毛片视频免费观看
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-TRIM25/BF488 Conjugated antibody (bs-4170R-BF488)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-4170R-BF488
英文名稱 Rabbit Anti-TRIM25/BF488 Conjugated antibody
中文名稱 BF488標記的雌激素反應鋅指蛋白抗體
別    名 EFP; Estrogen responsive finger protein; RNF 147; RNF147; TRI25; TRIM 25; Tripartite motif containing 25; Tripartite motif containing protein 25; Z147; Zinc finger protein 147; Zinc finger protein 147 (estrogen responsive finger protein); ZNF 147; ZNF147; TRI25_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  免疫學  發(fā)育生物學  染色質和核信號  鋅指蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Cow, Sheep, )
產(chǎn)品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 71kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRIM25
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains, a RING, a B box type 1 and a B box type 2, and a coiled coil region. The protein localizes to the cytoplasm. The presence of potential DNA binding and dimerization transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.

Function:
Functions as an ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs.

Subunit:
Interacts (via SPRY domain) with DDX58 (via CARD domain). Interacts (via coiled coil) with influenza A virus NS1 protein; this interaction specifically inhibits TRIM25 multimerization and TRIM25-mediated DDX58 CARD ubiquitination, thereby suppressing DDX58 signal transduction.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Ubiquitous.

Post-translational modifications:
Auto-ISGylated.

Similarity:
Contains 1 B30.2/SPRY domain.
Contains 1 RING-type zinc finger.

Database links:
UniProtKB/Swiss-Prot: Q14258.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.a6308.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
国产麻豆精品精东影业AV网站 | 一区二区三区国模大胆 | 国产va免费精品高清在线 | 日韩精品久久久久久福利 | 色欲av伊人久久大香线蕉影院 | 无码A级毛片日韩精品 | 动漫精品视频一区二区三区 | 国产偷窥熟女精品视频大全 | 日韩毛片AV无码免费一区二区三区 | √8天堂资源地址中文在线 欧美精品成人一区二区在线观看 | 日本欧美激情视频二区 | 久久久精品国产亚洲AV综合 | 欧美日产国产精品日产 | 亚洲国产女人aaa毛片在线 | 国产大片内射1区2区 | 欧美一区二区视频在线观看 | 又长又大又粗又硬3p免费视频 | 性一交一乱一色一免费无遮挡 | 777久久国产精品无码专区 | 日本一区午夜爱爱 | 欧美最猛性xxxxx亚洲精品 | 农村诱奷小箩莉17部分 | 国产伦精品一区二区高清版 | 国产精品久久久久久久福利竹菊 | 国产亚洲精品女人久久久久久 | 日本高清不卡中文字幕视频 | 国产无遮挡又黄又爽在线视频 | 欧洲精品久久久久69精品 | 国产婷婷色综合AV蜜臀AV | 人妻美妇疯狂迎合系列视频 | 在线日韩制服中文字幕视频 | JAPANESE少妇出轨内射 | 国产精品免费一区二区区 | 国产黄片高清无码在线观看 | 亚洲乱码国产乱码精品精乡村 | 高清精品美女在线播放 | 国产欧美日韩精品一区二区三区蜜桃不卡 | 99国产精品一区二区三区四区五区 | 中文字幕久久精品无码综合网 | 欧美日本在线不卡二区 | 国产精品扒开腿做爽爽爽 |