亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
最大胆裸体人体牲交666,国产AV无码国产AV毛片,公交车掀开奶罩边躁狠狠躁视频
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-TRIM25/PE-Cy7 Conjugated antibody (bs-4170R-PE-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-4170R-PE-Cy7
英文名稱 Rabbit Anti-TRIM25/PE-Cy7 Conjugated antibody
中文名稱 PE-Cy7標記的雌激素反應(yīng)鋅指蛋白抗體
別    名 EFP; Estrogen responsive finger protein; RNF 147; RNF147; TRI25; TRIM 25; Tripartite motif containing 25; Tripartite motif containing protein 25; Z147; Zinc finger protein 147; Zinc finger protein 147 (estrogen responsive finger protein); ZNF 147; ZNF147; TRI25_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  免疫學  發(fā)育生物學  染色質(zhì)和核信號  鋅指蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Cow, Sheep, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 71kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRIM25
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains, a RING, a B box type 1 and a B box type 2, and a coiled coil region. The protein localizes to the cytoplasm. The presence of potential DNA binding and dimerization transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.

Function:
Functions as an ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs.

Subunit:
Interacts (via SPRY domain) with DDX58 (via CARD domain). Interacts (via coiled coil) with influenza A virus NS1 protein; this interaction specifically inhibits TRIM25 multimerization and TRIM25-mediated DDX58 CARD ubiquitination, thereby suppressing DDX58 signal transduction.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Ubiquitous.

Post-translational modifications:
Auto-ISGylated.

Similarity:
Contains 1 B30.2/SPRY domain.
Contains 1 RING-type zinc finger.

Database links:
UniProtKB/Swiss-Prot: Q14258.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
久久成人国产精品一区二区 | 中文字幕在线免费观看视频 | 久久午夜夜伦鲁鲁片不卡 | 国产成a人亚洲精v品久久网 | 亚洲AV成人无码网天堂 | 国产精品久久一区二区三蜜桃 | 亚洲一区在线播放 | 国产SUV精品一区二区 | 中文字幕久久久久久久免费 | 日韩丰满少妇无吗视频激情内射 | 国产99久久久国产精品小说 | 一二三四社区在线中文视频 | 午夜福利视频合集1000 | 青草园网站在线观看 | 女人一级毛片免费观看 | 啊灬啊灬啊灬快灬高潮了听书 | 国产精品嫩草影视在线观看 | 欧美一区二区视频在线观看 | 97久精品国产片一区二区三区 | 亚洲中文字幕乱码免费播放 | 久久只这里是精品66 | 狠狠色噜噜狠狠狠777 | 搡BBBB搡BBB搡 | 性一交一无一伦一精一品 | 一本到无码高清手机字幕在线播放 | 人妻仑乱少妇88MAV | 亚洲中文字幕在线第六区 | 1024国产欧美日韩精品 | 无码人妻丰满熟妇片毛片 | 免费精品国产日韩热久久 | 九九热视频在线观看 | 亚洲精品无码不卡在线播HE | 日韩欧美国产丝袜大香蕉 | 久久线看在观草草青青脱裤 | 黑人啊灬啊灬啊灬快灬深用口述 | 超碰97人人做人人爱亚洲尤物 | 久久夜色国产亚洲色欲AV | 亚洲最大的视频网站 | A级成人毛片免费视频高清 国产高清japanese国产 | 黄色在线观看www | 香港三级精品三级在线专区 |