亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
最大胆裸体人体牲交666,国产AV无码国产AV毛片,公交车掀开奶罩边躁狠狠躁视频
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-TRIM25/PE-Cy7 Conjugated antibody (bs-4170R-PE-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-4170R-PE-Cy7
英文名稱 Rabbit Anti-TRIM25/PE-Cy7 Conjugated antibody
中文名稱 PE-Cy7標記的雌激素反應(yīng)鋅指蛋白抗體
別    名 EFP; Estrogen responsive finger protein; RNF 147; RNF147; TRI25; TRIM 25; Tripartite motif containing 25; Tripartite motif containing protein 25; Z147; Zinc finger protein 147; Zinc finger protein 147 (estrogen responsive finger protein); ZNF 147; ZNF147; TRI25_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  免疫學  發(fā)育生物學  染色質(zhì)和核信號  鋅指蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Cow, Sheep, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 71kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRIM25
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains, a RING, a B box type 1 and a B box type 2, and a coiled coil region. The protein localizes to the cytoplasm. The presence of potential DNA binding and dimerization transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.

Function:
Functions as an ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs.

Subunit:
Interacts (via SPRY domain) with DDX58 (via CARD domain). Interacts (via coiled coil) with influenza A virus NS1 protein; this interaction specifically inhibits TRIM25 multimerization and TRIM25-mediated DDX58 CARD ubiquitination, thereby suppressing DDX58 signal transduction.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Ubiquitous.

Post-translational modifications:
Auto-ISGylated.

Similarity:
Contains 1 B30.2/SPRY domain.
Contains 1 RING-type zinc finger.

Database links:
UniProtKB/Swiss-Prot: Q14258.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
一区二区三区无码成人无码 | 国产真实女人一级毛片 | 超碰97久久久久久久久久久 | 亚洲mv大片欧洲mv大片免费 | 久久久久精品日韩久久久 | 777久久国产精品无码专区 | 亚洲欧洲校园自拍都市 | 国产口爆吞精在线观看视频 | 无码纯肉国产麻豆久久 | 蜜桃视频一区二区 | 亚洲高清在线精品一区 | 一级做a爱全免费视频99 | 国产真人无遮挡作爱免费视频 | 偷拍激情视频一区二区三区 | 国产又黄又爽又猛免费app | 97精品国产高清久久久久 | 色国产在线视频一区 | 少妇性荡欲午夜性开放视频剧场 | 欧美日韩精品一区二区三区高清视频 | 亚洲精品动漫免费二区 | 国产精品久久久久国产A级 999国内精品永久免费视频 | 韩国三级理论在线电影 | 欧美日产国产精品日产 | 国产无线乱码一区二三区 | 惩罚抽插校花嗯啊白浆 | 国产日韩亚洲VA无码自线免费看不卡 | 最近中文字幕在线看免费完整版 | 精品91网站在线观看 | 国产精品欧美激情第一页 | 精品91自产拍在线观看二区 | 精品国产乱码欠欠欠欠精品 | 久久精品国产亚洲AV麻豆 | 99re66在线观看精品免费 | 精品国产一区二区三区AV性色 | 亚洲AV中文无码字幕色三 | 国产成人自产拍免费视频 | 最近最新精品欧美日本韩亚洲中文国产 | 日本一级婬片A片免费播放曰i | 白丝乳交内射一二三区 | 九九在线精品视频xxx | 国产免费成人在线视频 |