亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
久久国内精品自在自线,国产网红在线_电影频道,懂色av无码aV天天aV天天爽
Rabbit Anti-TRIM25/BF594 Conjugated antibody (bs-4170R-BF594)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-4170R-BF594
英文名稱 Rabbit Anti-TRIM25/BF594 Conjugated antibody
中文名稱 BF594標(biāo)記的雌激素反應(yīng)鋅指蛋白抗體
別    名 EFP; Estrogen responsive finger protein; RNF 147; RNF147; TRI25; TRIM 25; Tripartite motif containing 25; Tripartite motif containing protein 25; Z147; Zinc finger protein 147; Zinc finger protein 147 (estrogen responsive finger protein); ZNF 147; ZNF147; TRI25_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  免疫學(xué)  發(fā)育生物學(xué)  染色質(zhì)和核信號  鋅指蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng)
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 71kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRIM25
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains, a RING, a B box type 1 and a B box type 2, and a coiled coil region. The protein localizes to the cytoplasm. The presence of potential DNA binding and dimerization transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.

Function:
Functions as an ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs.

Subunit:
Interacts (via SPRY domain) with DDX58 (via CARD domain). Interacts (via coiled coil) with influenza A virus NS1 protein; this interaction specifically inhibits TRIM25 multimerization and TRIM25-mediated DDX58 CARD ubiquitination, thereby suppressing DDX58 signal transduction.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Ubiquitous.

Post-translational modifications:
Auto-ISGylated.

Similarity:
Contains 1 B30.2/SPRY domain.
Contains 1 RING-type zinc finger.

Database links:
UniProtKB/Swiss-Prot: Q14258.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
a毛片免费全部播放无风险 www.一级毛片 | 国产美女一区二区 | 最近2019年中文字幕无吗 | 成人国产欧美大片一区 | 男女牲交全程播放免费 | 日日噜噜噜夜夜爽爽狠狠 | 亚洲第一区欧美国产不卡综合 | 中国特级黄一级**毛片 | 久久国产精品高清一区二区三区 | 91精品国产综合久久久久久一区黄网无码 | 欧美日韩国产码综合一区在线 | 最新国产精品自在自线发布 | 1024国产欧美日韩精品 | 奇米综合四色77777久久 | 推油少妇久久99久久99久久 | 欧洲一二三区免费视频 | 91精品久久久久久中文字幕 | 亚洲黄色一级大片 | 久久久av久av久片一区二区 | 日本免费在线观看视频 | 久久久久久91香蕉国产 | 日本在线视频一区 | 国产第一页浮力影院草草 | 文中字幕一区二区三区视频播放 | 中文字幕日本最新乱码视频 | 24小时日本免费观看高清视频 | 无限资源好看片高清在线 | 91青青青国产在线观看免费2019 | 肉大捧一进一出免费视频 | 国产欧美日韩网站 | 国产麻豆天美果冻无码视频 | 97亚洲熟妇自偷自拍另类图片 | VR虚拟专区亚洲精品二区 | 国产精品xxxav免费视频 | 精品乱码一区内射人妻无码 | 日日噜噜噜夜夜爽爽狠狠 | 日本高清VA在线播放 | 亚洲国产无线乱码在线观看 | 最美情侣高清免费观看在线 | 亚洲色婷婷综合久久二区 | 亚洲国产精品特色大片观看完整版 |