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Rabbit Anti-GPR39/AP Conjugated antibody (bs-5789R-AP)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-5789R-AP
英文名稱 Rabbit Anti-GPR39/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標(biāo)記的G蛋白偶聯(lián)受體39抗體
別    名 GPCR GPR39; G protein coupled receptor GPR39; G Protein-Coupled Receptor 39; GPR 39; GPR39; GPR-39; MGC149541.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞膜受體  G蛋白偶聯(lián)受體  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 51kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPR39.
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
GPCR39 is an integral membrane protein, which belongs to family 1 of G-protein coupled receptors. GPCR39 expression has been documented in human brain and peripheral tissues. ESTs have been isolated from human tissue libraries, including normal eye, brain, heart, melanocyte, uterus, vessel, cancerous brain, germ cell, kidney, and ovary.

Function:
Zn(2+) acts as a agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death.

Subcellular Location:
Multi-pass membrane protein

Tissue Specificity:
Expressed in many tissues, including the stomach, intestine and hypothalamus.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 2863 Human

Entrez Gene: 71111 Mouse

Entrez Gene: 288995 Rat

Omim: 602886 Human

SwissProt: O43194 Human

SwissProt: Q5U431 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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