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Rabbit Anti-Growth Arrest Specific Protein 7/BF488 Conjugated antibody (bs-4279R-BF488)
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說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-4279R-BF488
英文名稱 Rabbit Anti-Growth Arrest Specific Protein 7/BF488 Conjugated antibody
中文名稱 BF488標(biāo)記的生長(zhǎng)休止特定蛋白7抗體
別    名 GAS 7; GAS-7; Gas7; GAS7_HUMAN; Growth arrest specific 7; Growth arrest-specific protein 7; KIAA0394; MGC1348; MLL/GAS7; MLL/GAS7 fusion protein.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  染色質(zhì)和核信號(hào)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞周期蛋白  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 54kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GAS7/Growth Arrest Specific Protein 7
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Growth arrest specific 7 is expressed primarily in terminally differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. It may play a role in neuronal development by promoting maturation and morphological differentiation of cerebellar neurons. Several transcript variants encoding proteins which vary in the N terminus have been described.

Function:
May play a role in promoting maturation and morphological differentiation of cerebellar neurons.

Subcellular Location:
Cytoplasm (By similarity).

DISEASE:
Note=A chromosomal aberration involving GAS7 is found in acute myeloid leukemia. Translocation t(11;17)(q23;p13) with MLL/HRX.

Similarity:
Contains 1 FCH domain.
Contains 1 SH3 domain.
Contains 1 WW domain.

Database links:

Entrez Gene: 8522 Human

Omim: 603127 Human

SwissProt: O60861 Human

SwissProt: O55148 Rat

Unigene: 258855 Human

Unigene: 462214 Human

Unigene: 17160 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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