亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
九九视频精品全部免费播放 ,欧美精品一本久久男人的天堂
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-ADAM12/APC Conjugated antibody (bs-4977R-APC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-4977R-APC
英文名稱 Rabbit Anti-ADAM12/APC Conjugated antibody
中文名稱 APC標記的去整合素樣金屬蛋白酶12
別    名 MLTN; A disintegrin and metalloproteinase domain 12; A disintegrin and metalloproteinase domain 12; ADA12_HUMAN; ADAM 12; ADAM metallopeptidase domain 12; ADAM12; Disintegrin and metalloproteinase domain-containing protein 12; MCMP; MCMPMltna; MCMPMltna; Meltrin alpha; Meltrin-alpha; MLTN; MLTNA; OTTHUMP00000046766.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  細胞粘附分子  細胞骨架  細胞外基質(zhì)  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Rabbit, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 77/100kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ADAM12/MLTN
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
產(chǎn)品介紹 background:
ADAM (a disintegrin and metalloprotease) proteins are a family of over 30 membrane-anchored, glycosylated, Zn2+ dependent proteases that are involved in cell-cell, cell-matrix interface related processes including fertilization, muscle fusion, secretion of TNF?(tumor necrosis factor ?, and modulation of the neurogenic function of Notch and Delta (1-3). ADAM proteins possess a signal-domain, a pro-domain, a metalloprotease domain, a disintegrin domain (Integrin ligand), a cysteine-rich region, an epidermal growth factor-like domain, a transmembrane domain and a cytoplasmic tail (1-3). ADAMs are expressed in brain, testis, epididymis, ovary, breast, placenta, liver, heart, lung, bone, and muscle, and catalyze proteolysis, adhesion, fusion, and intracellular signaling (3). ADAM 12 (Meltrin-a) is produced as 2 differentially spliced isoforms, a 718 amino acid secreted form (ADAM12S) and a 881 amino acid membrane-bound form (ADAM12L), and is involved in egg-sperm fusion (4-6).

Function:
Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors (By similarity).

Subunit:
Interacts with alpha-actinin-2 and with syndecans (By similarity). Interacts with SH3PXD2A. Interacts with FST3. Interacts with GNB2L1/RACK1; the interaction is required for PKC-dependent translocation of ADAM12 to the cell membrane.

Subcellular Location:
Isoform 1: Cell membrane; Single-pass type I membrane protein.
Isoform 2: Secreted.
Isoform 3: Secreted (Potential).
Isoform 4: Secreted (Potential).

Tissue Specificity:
Isoform 1 is expressed in placenta and skeletal, cardiac, and smooth muscle. Isoform 2 seems to be expressed only in placenta or in embryo and fetus. Both forms were expressed in some tumor cells lines. Not detected in brain, lung, liver, kidney or pancreas.

Post-translational modifications:
The precursor is cleaved by a furin endopeptidase (By similarity).

Similarity:
Contains 1 disintegrin domain.
Contains 1 EGF-like domain.
Contains 1 peptidase M12B domain.

Database links:

Entrez Gene: 8038 Human

Entrez Gene: 11489 Mouse

Entrez Gene: 679837 Rat

Omim: 602714 Human

SwissProt: O43184 Human

SwissProt: Q61824 Mouse

Unigene: 594537 Human

Unigene: 439714 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
亚洲欧美码明星卡通重口 | **毛片免费观看久久精品 | 么公又大又硬又粗又长 | 最近免费中文字幕MV免费高清版 | 丰满白嫩尤物啪啪嗯啊动态图 | 欧美性爱视频在线播放 | 亚洲精品高清一二区久久 | 欧美日本在线不卡二区 | 国产成+人+综合+欧美亚洲 | 真人一级一级毛片免费观看 | 艳妇乳肉豪妇荡乳AV无码福利 | 影音先锋女人AA鲁色资源 | 13小箩利无码视频网站免费 | 内射无码AV-区二区三区 | 中文字幕人妻熟女人妻A片 亚洲AV成人一区二区三区在线看 | 青青青免费高清在线观看一区二区 | 性夜影院爽黄A爽免费动漫 亚洲黄色一级大片 | 亚洲日韩一区在线观看 | 亚洲无线一二三四区手机 | 国产精品第1页在线观看 | 欧美亚洲另类丝袜自拍动漫 | 一级毛片正片免费视频手机看 | 亚洲AV无码乱码国产麻豆穿越 | 免费观看成人久久网免费观看 | 真人后进式啪啪GIF动态图 | 亚洲日韩中文字幕A∨ | 久久九九日本韩国精品 | 91视频一区二区三区 | 国产在线观看www | 给我免费播放片在线中国 | 91网站网站网站在线 | 国产成人精品自产拍在线观看 | 真人插B免费视频播放 | GOGO人体大胆全球少妇 | 欧美va欧美va在线 | 高潮又爽又大又黄无遮挡免费 | 日本系列1页亚洲系列 | 免费观看成人久久网免费观看 | 最近免费中文字幕大全免费版视频 | 精品国产乱码久久久久久软件大全 | 欧美两根一起进3p在线观看 |