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Rabbit Anti-ZNF346/Biotin Conjugated antibody (bs-12235R-Bio)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-12235R-Bio
英文名稱 Rabbit Anti-ZNF346/Biotin Conjugated antibody
中文名稱 生物素標(biāo)記的鋅指蛋白346抗體
別    名 DKFZp547M223; Double stranded RNA binding zinc finger protein; Double stranded RNA binding zinc finger protein JAZ; JAZ; Just another zinc finger protein; Zfp346; Zinc finger protein 346; ZN346_HUMAN; Znf346.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  鋅指蛋白  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 33kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Human ZNF346
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF346 (Zinc finger protein 346), also known as JAZ (Just another zinc finger protein), is a 294 amino acid protein that contains four matrin-type zinc fingers. The matrin-type zinc finger, which is very similar in structure to the classical DNA-binding C2H2 zinc finger, was first identified in the protein matrin-3. The matrin-type zinc finger has also been identified in several spliceosome RNA-binding proteins. Two isoforms exists due to alternate splicing events.

Function:
Binds to dsRNA and DNA.

Subunit:
Forms a heteromeric complex with XPO5 and ILF3. Found in a nuclear export complex with XPO5, RAN, ILF3, ZNF346 and double-stranded RNA. Interacts with XPO5. Interacts with ILF3 in an RNA-independent manner.

Subcellular Location:
Nucleus Cytoplasm.

Similarity:
Contains 4 matrin-type zinc fingers.

Database links:

Entrez Gene: 23567 Human

Entrez Gene: 26919 Mouse

Entrez Gene: 306765 Rat

Omim: 605308 Human

SwissProt: Q9UL40 Human

SwissProt: Q9R0B7 Mouse

Unigene: 484259 Human

Unigene: 671568 Human

Unigene: 22795 Mouse

Unigene: 17764 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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