亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
欧美另类精品xxxx,午夜欧美精品久久久久久久
Rabbit Anti-DGCR8/Gold Conjugated antibody (bs-14293R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-14293R-Gold
英文名稱 Rabbit Anti-DGCR8/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的狄喬治(DiGeorge)氏綜合征相關(guān)蛋白8抗體
別    名 DGCRK6; C22orf12; D16H22S788E; D16Wis2; DGCR 8; Dgcr8; DGCR8_HUMAN; DGCRK 6; DGCRK6; DiGeorge syndrome critical region 8; DiGeorge syndrome critical region gene 8; Gy1; Microprocessor complex subunit DGCR8; pasha.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 發(fā)育生物學(xué)  染色質(zhì)和核信號  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chimpanzee, Rhesus monkey, Gorilla, Orangutan)
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 86kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DGCR8
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

Function:
Component of the microprocessor complex that acts as a RNA- and heme-binding protein that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs DROSHA to cleave 11 bp away form the junction to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. The heme-bound DGCR8 dimer binds pri-miRNAs as a cooperative trimer (of dimers) and is active in triggering pri-miRNA cleavage, whereas the heme-free DGCR8 monomer binds pri-miRNAs as a dimer and is much less active. Both double-stranded and single-stranded regions of a pri-miRNA are required for its binding. Involved in the silencing of embryonic stem cells self-renewal.

Subcellular Location:
Nucleus. Nucleus; nucleolus. Colocalizes with nucleolin and DROSHA in the nucleolus. Mostly detected in the nucleolus as electron-dense granular patches around the fibrillar center (FC) and granular component (GC). Also detected in the nucleoplasm as small foci adjacent to splicing speckles near the chromatin structure. Localized with DROSHA in GW bodies (GWBs), also known as P-bodies.

Tissue Specificity:
Ubiquitously expressed.

Similarity:
Contains 2 DRBM (double-stranded RNA-binding) domains.
Contains 1 WW domain.

Database links:

Entrez Gene: 54487 Human

Omim: 609030 Human

SwissProt: Q8WYQ5 Human

Unigene: 643452 Human

Unigene: 713579 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
午夜久久久久久禁播电影 | 热热久久超碰精品中文字幕 | 国产香蕉九九久久精品免费 | 国产v综合v亚洲欧美大片 | 国产精品v欧美精品v日韩精品 | 日韩人妻无码精品-专区 | h嗯啊~玉足稚嫩奶娃脚乱女 | 最新上传免费网友自拍视频 | 久久精品天天爽夜夜爽 | 国产精品系列在线观看 | 最新黄色网址在线观看 | 国产成人AV一区二区在线观看 | 精品国产午夜肉伦伦影院 | 日韩免费一区二区三区在线 | 中文字幕国产精品高潮呻吟久久av无码 | 国产一区二区高清 | 一区二区日本视频 | 亚洲第一区第二区 | 免费无码一区二区三区蜜桃大 | 久久免费看少妇高潮喷水 | 国产精品99久久精品爆乳 | 无套内射AV二区 | 精品一级 片内射视网站 | 久久久精品无码一二三区 | 国产精品美女免费视频观看 | 伴郎粗大的内捧猛烈进出视频观看 | 麻婆豆传媒一区二区三 | 国产后进白嫩翘臀在线动漫 | 在线观看黄色视频网站 | 久久狠狠爱亚洲综合影院 | 日韩一区二区免费视频 | 内射中出日韩无国产剧情 | 国产AV一区二区三区最新精品 | 午夜夫妻试看120国产 | 国产欧美一区二区精品性色超碰 | 精品国产髙清在线看国产毛片 | 无码精品A∨在线观看中文 欧美激情视频在线观看一区二区三区 | 欧美综合区自拍亚洲综合天堂 | 麻豆精品久久久一区二区 | YW193.CAN尤物国产在线网页 | 么公又大又硬又粗又长 |