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Rabbit Anti-KCNG3/Gold Conjugated antibody (bs-12175R-Gold)
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說(shuō) 明 書(shū): 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-12175R-Gold
英文名稱 Rabbit Anti-KCNG3/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的電壓門(mén)控性鉀通道蛋白亞基KV6.3抗體
別    名 KCNG 3; Kcng3; KCNG3_HUMAN; KV10.1; Kv10.1a; Kv10.1b; KV6.3; OTTHUMP00000201478; OTTHUMP00000201479; Potassium voltage gated channel subfamily G member 3; Potassium voltage-gated channel subfamily G member 3; Voltage gated potassium channel 6.3; Voltage gated potassium channel Kv10.1; Voltage gated potassium channel subunit Kv10.1; Voltage gated potassium channel subunit Kv6.3; Voltage gated potassium channel subunit Kv6.4; Voltage-gated potassium channel subunit Kv10.1; Voltage-gated potassium channel subunit Kv6.3.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  通道蛋白  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCNG3
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a gamma subunit functioning as a modulatory molecule. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].

Function:
Potassium channel subunit. Modulates channel activity.

Subunit:
Heteromultimer with KCNB1, KCNC1 and KCNF1. Does not form homomultimers.

Subcellular Location:
Cell membrane. Membrane. Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB1.

Tissue Specificity:
Detected in many parts of the brain with the exception of the cerebellum, in testis, pancreas, lung, kidney, ovary, small intestine, colon, thymus, adrenal gland and spinal cord.

Similarity:
Belongs to the potassium channel family.
G (TC 1.A.1.2) subfamily. Kv6.3/KCNG3 sub-subfamily.

Database links:

Entrez Gene: 170850 Human

Entrez Gene: 225030 Mouse

Entrez Gene: 171011 Rat

Omim: 606767 Human

SwissProt: Q8TAE7 Human

SwissProt: P59053 Mouse

SwissProt: Q8R523 Rat

Unigene: 352633 Human

Unigene: 223506 Mouse

Unigene: 82689 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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