亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国产精品三级在线观看,国产精品一区二区在线观看99
Rabbit Anti-APC10/BF555 Conjugated antibody (bs-12483R-BF555)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-12483R-BF555
英文名稱 Rabbit Anti-APC10/BF555 Conjugated antibody
中文名稱 BF555標(biāo)記的細(xì)胞周期后期促進(jìn)蛋白亞基10抗體
別    名 ANAPC 10; anapc10; Anaphase promoting complex 10; Anaphase promoting complex subunit 10; Anaphase-promoting complex subunit 10; Apc 10; APC10; APC10_HUMAN; Cyclosome subunit 10; DKFZP564L0562; Doc 1; Doc1; OTTHUMP00000220297; OTTHUMP00000220298; OTTHUMP00000220299; OTTHUMP00000220300; OTTHUMP00000220303.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  細(xì)胞周期蛋白  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 21kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human APC10
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Composed of more than ten subunits, the anaphase-promoting complex (APC) acts in a cell-cycle dependent manner to promote the separation of sister chromatids during the transition between metaphase and anaphase in mitosis. APC, or cyclosome, accomplishes this progression through the ubiquitination of mitotic cyclins and other regulatory proteins that are targeted for destruction during cell division. APC is phosphorylated, and thus activated, by protein kinases Cdk1/cyclin B and polo-like kinase (Plk). APC is under tight control by a number of regulatory factors, including CDC20, CDH1 and MAD2. Specifically, CDC20 and CDH1 directly bind to and activate the cyclin-ubiquitination activity of APCs. In contrast, MAD2 inhibits APC by forming a ternary complex with CDC20 and APC, thus preventing APC activation. APC10 contains a Doc1 homology domain, which is a beta-sandwich structure common to many other putative E3 ubiquitin ligases. APC10 binds to core APC subunits throughout the cell cycle. Specifically, APC10 binds to the C-terminus of CDC27/APC3. During mitosis, APC10 is localized in centrosomes and mitotic spindles. APC10 also localizes to kinetochores from prophase to anaphase, and to the midbody in telophase and cytokinesis.

Function:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

Subunit:
The APC/C is composed of at least 12 subunits. The C-terminus of APC10 binds to CDC27/APC3.

Similarity:
Belongs to the APC10 family.
Contains 1 DOC domain.

Database links:
UniProtKB/Swiss-Prot: Q9UM13.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
国产精品成人99久久久久 | 国产一级精品免费看高清99 | 狼人香蕉香蕉在线28 | 久久国产欧美日韩精品免费 | 免费看撕开奶罩揉吮奶头视频 | 免费观看黄色毛片 | 五月天婷亚洲天综合网 | 宝贝乖调教跪趴SM主人玩具HH | 精品国产乱码久久久久久久小说 | 宝贝腿开大点我添添公视频免费 | 久久无码精品一区二区三区 | 美女赤裸裸一丝不遮的图片动图 | 成年免费A级毛片免费看无码 | 久久av无码av高潮av喷吹捆绑 | 野花香日本大全免费观看 | 国产欧美精品一区二区色综合 | 亚洲线精品一区二区三区八戒 | 高清有码国产一区二区 | 日韩AV片无码一区二区三区不卡 | 我穿短裙被同桌cao得好爽 | 高清欧美一区二区三区 | 国产乱老熟视频乱老熟女51 | 羞羞漫画官方页面弹窗 | 国产精品k频道在线看 | AV毛片无码乱码国产精品 | 性色爽爱性色爽爱网站 | 小sao货水好多真紧 亚洲综合色婷婷七月丁香 国产精品内射久久久久欢欢 | 国产a视频精品免费观看 | 性xxxxbbbb免费播放视频 | 最新国学生自产拍短视频 | 国产99视频在线观看 | 国产精品爱啪在线播放 | 亚洲无线一二三四区手机 | 欧美97色伦欧美一区二区日韩 | 免费A级毛片无码无遮挡内射 | 国产精品视频第一区二区三区 | 国产精品高潮呻吟久久av无码 | 又黄又湿真实网站不付费 | 免费的很污的很黄的网站 | 国产三级视频在线播放线观看 | 国产精品99久久久久久 |