亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯(lián)系我們
YW193.CAN尤物国产在线网页,综合久久国产九一剧情麻豆 ,日本三级电影在线看
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-NR1H4/BF647 Conjugated antibody (bs-12867R-BF647)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-12867R-BF647
英文名稱 Rabbit Anti-NR1H4/BF647 Conjugated antibody
中文名稱 BF647標記的膽汁酸受體抗體
別    名 Bile Acid Receptor NR1H4; BAR; FXR; Farnesoid X activated receptor; Farnesoid X receptor; Farnesoid X-activated receptor; Farnesol receptor HRR 1; Farnesol receptor HRR-1; Farnesol receptor HRR1; FXR; HRR 1; HRR1; NR1H4; NR1H4_HUMAN; Nuclear receptor subfamily 1 group H member 4; Retinoid X receptor interacting protein 14; Retinoid X receptor-interacting protein 14; RIP 14; RIP14; RXR interacting protein 14; RXR-interacting protein 14.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  信號轉導  新陳代謝  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Horse, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 56kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FXR/Bile Acid Receptor NR1H4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The steroid receptor superfamily acts through direct association with DNA sequences known as hormone response elements (HREs) and binds DNA as either homo- or heterodimers. The promiscuous mediator of heterodimerization, RXR, is the receptor for 9-cis retinoic acid, and dimerizes with VDR, TR, PPAR, and several novel receptors including LXR (also referred to as RLD-1) and FXR. FXR and LXR fall into a category of proteins termed “orphan receptors” because of their lack of a defined function, and in the case of LXR, the lack of a defined ligand. FXR has been shown to bind a class of lipid molecules called farnesoids. LXR/RXR heterodimers have highest affinity for DR-4 DNA elements while FXR/RXR heterodimers bind IR-1 elements. Both LXR/RXR and FXR/RXR heterodimers retain their responsiveness to 9-cis retinoic acid.

Function:
Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two distinct mechanisms. Activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus.

Subunit:
eterodimer of NR1H4 and RXR. After activation by agonist binding, interacts with a coactivator, NCOA1 or NCOA2 (By similarity). Interacts with CARM1 and SMARD1.

Subcellular Location:
Nucleus.

Post-translational modifications:
Methylation may increase transactivation of target genes.

Similarity:
Belongs to the nuclear hormone receptor family. NR1 subfamily.
Contains 1 nuclear receptor DNA-binding domain.

Database links:

Entrez Gene: 9971 Human

Entrez Gene: 20186 Mouse

Entrez Gene: 60351 Rat

Omim: 603826 Human

SwissProt: Q96RI1 Human

SwissProt: Q3V1T8 Mouse

SwissProt: Q60641 Mouse

SwissProt: Q5XI75 Rat

SwissProt: Q62735 Rat

Unigene: 282735 Human

Unigene: 3095 Mouse

Unigene: 42943 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.a6308.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
亚1州区2区3区4区产品图片 | 成年女人毛片免费播放视频m | 亚洲国产精品一区二区久久 | 无码不卡中文字幕一区二区三区 | 国产无遮挡色视频免费观看性色 | 久久久久久亚洲综合网站 | 两个人看的www视频中文字幕 | 国产-第1页-浮力影院 | 人妻美妇疯狂迎合系列视频 | 国产精品白浆无码流出AV动漫 | 国产 浪潮AV性色四虎 | 欧美人与动牲交A精品 | 91欧美人妻白浆喷潮在线不卡 | 午夜精品久久久久久影视riav | 无码AV大香线蕉伊人久久九色 | 国内精品久久久久影院老司 | 一本一道精品欧美中文字幕 | 美女赤裸裸一丝不遮的图片动图 | 在线播放无码后入内射少妇 | 性高湖久久久久久久久 | 狠狠色丁香婷婷综合 | 免费可以看黄的视频s色 | 日本wwwxx爽69护士 | 久久人人做人人爽久久99国产乱子伦精品免 | 国产午夜福利不卡在线观看 | 影音先锋女人av鲁色资源网久久 | 91亚洲精品无码久久久久 | 一二三四视频免费社区5 | 国模冰莲2013肥美人体自慰w | 日韩精品欧美视频 | 精品久久久久成人码免费动漫 | 老头埋进校花里面使劲添 | 欧美激情二区三区 | 国产亚洲精品女人久久久久久 | 中文字幕精品久久久人妻特粗粗大 | 人妻体体内射精一区二区三区电影 | www.一级毛片| 日韩人妻无码精品系列 | 《久久国产91成人免费网站 | 国语A在线看免费观看视频 我和闺蜜在公车被cao污文 | 欧美大片AAAAA免费观看 |