亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
成人片黄网站色大片免费,国产AV一区二区三区,国产成人精品午夜福利在线播放
Rabbit Anti-UBR5/Cy7 Conjugated antibody (bs-13052R-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-13052R-Cy7
英文名稱 Rabbit Anti-UBR5/Cy7 Conjugated antibody
中文名稱 Cy7標(biāo)記的E3泛素蛋白連接酶EDD抗體
別    名 4432411E13Rik; AW549941; C77315; D030042K14; DD5; E3 identified by differential display; E3 ubiquitin protein ligase, HECT domain containing, 1; E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase UBR5; EDD 1; EDD; EDD1; FLJ11310; HECT domain-containing 1; hHYD; HYD; Hyperplastic discs protein homolog; KIAA0896; MGC57263; mKIAA0896; Progestin induced protein; Progestin-induced protein; Rat100; Ubiquitin protein ligase; Ubiquitin protein ligase E3 component n recognin 5; UBR5; UBR5_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  表觀遺傳學(xué)  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Horse, Sheep, )
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 309kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human EDD
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
EDD is a progestin-regulated gene that was isolated from T-47D human breast cancer cells. Based on sequence homology, EDD appears to be a human homolog of the Drosophila hyperplastic discs (hyd) gene, a tumor suppressor gene that is required for control of imaginal disc growth. EDD contains a HECT domain in the carboxy terminus. HECT domain-containing proteins function as ubiquitin-protein ligases, or E3 enzymes. EDD has been shown to bind to ubiquitin, and like other HECT family proteins, may function as an E3 ubiquitin-protein ligase.

Function:
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific amino-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (By similarity). May be involved in maturation and/or transcriptional regulation of mRNA. May play a role in control of cell cycle progression. May have tumor suppressor function. Regulates DNA topoisomerase II binding protein (TopBP1) in the DNA damage response. Plays an essential role in extraembryonic development.

Subunit:
Binds TOPBP1. Associates with CDK9 and TFIIS/TCEA1 and forms a transcription regulatory complex made of CDK9, RNAP II, UBR5 and TFIIS/TCEA1 that can stimulate target gene transcription (e.g. gamma fibrinogen/FGG) by recruiting their promoters. Associates with the E3 ligase complex containing DYRK2, EDD/UBR5, DDB1 and VPRBP proteins (EDVP complex). Interacts directly with DYRK2.

Subcellular Location:
Nucleus.

Tissue Specificity:
Widely expressed. Most abundant in testis and expressed at high levels in brain, pituitary and kidney.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.
Contains 1 PABC domain.
Contains 1 UBR-type zinc finger.

Database links:

Entrez Gene: 515582 Cow

Entrez Gene: 51366 Human

Entrez Gene: 70790 Mouse

Entrez Gene: 100157625 Pig

Entrez Gene: 117060 Rat

Omim: 608413 Human

SwissProt: O95071 Human

SwissProt: Q80TP3 Mouse

SwissProt: Q62671 Rat

Unigene: 492445 Human

Unigene: 476840 Mouse

Unigene: 54812 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
91精品国产色综合久久不8 | 内射白嫩少妇超碰 | 一级毛片在线播放观看 | AV无码免费一区二区三区不卡 | JEALOUSVUE极品少妇 | 99久久免费看国产精品 | 日韩精品免费在线观看 | 欧洲亚洲精品A片久久99果冻 | 日本丰满熟妇被捏出奶水 | 美女内射毛片在线看3D | 人妻无码制服丝袜欧美日韩 | 免费一级欧美片片线观看 | 国产嫖妓一区二区三区无码 | 久久一区二区三区精华液使用方法 | 一级a一级a爰片免费免免2021 | 俺去俺来也在线www色官网 | 免费看国产曰批40分钟 | 中文字幕在线观看国产 | 乱码午夜-极品国产内射 | 国产黄片高清无码在线观看 | 伊人激情AV一区二区三区 | 欧美日韩一区二区三区自拍 | 精品91自产拍在线观看二区 | 一级av一片久久免费观看 | 欧美性猛交XXXX乱大交 | 日韩中文字幕免费的视频在线看网站 | 久久久97精品国产一区蜜桃 | 中文在线а√天堂官网 | 在线观看黄网视频免费播放 | 啊轻点内射在线视频 | 精品一区二区久久久久久久网精 | 超级乱淫小黄文小说 | 日韩精品亚洲一区二区三区 | 少妇内射兰兰久久 | 国产精品反差婊在线观看 | 加勒比高清无码二区在线三级免费电影dvd | 久色乳综合思思在线视频 | AV无码免费一区二区三区不卡 | 精品水蜜桃久久久久久久 | 麻花传媒永久免费版的特色 | 日韩在线视频播放一区二区三区 |