亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質(zhì)量反饋  關于我們  聯(lián)系我們
每日更新在线观看av,亚洲黄色网站免费观看
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-ARID1B/Cy5 Conjugated antibody (bs-12520R-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-12520R-Cy5
英文名稱 Rabbit Anti-ARID1B/Cy5 Conjugated antibody
中文名稱 Cy5標記的抑癌基因結合蛋白ARID1B抗體
別    名 6A3 5; ARID 1B; ARID domain containing protein 1B; AT rich interactive domain 1B (SWI1 like); AT rich interactive domain 1B; AT rich interactive domain containing protein 1B; BAF 250b; BAF250b; BRG1 associated factor 250b; BRG1 binding protein; BRG1 binding protein ELD/OSA1; BRG1 binding protein hELD/OSA1; BRIGHT; DAN 15; DAN15; Eld (eyelid)/Osa protein; ELD/OSA1; hELD/OSA1; hOsa 2; hOsa2; KIAA1235; OSA 2; Osa homolog 2; OSA2; OTTHUMP00000040115; p250R; RP11 419L10.1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  結合蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Sheep, )
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 236kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ARID1B
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2 alpha) and Brg-1 (also designated SNF2 beta) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits, such as BAF250 (p270 or ARID 1A) and BAF250b(ARID1B), are thought to play regulatory roles.

Function:
ARID1B (AT-rich interactive domain-containing protein 1B) is a component of SWI/SNF chromatin remodeling complexes involved in transcriptional activation and repression of select genes by chromatin remodeling. It binds DNA non-specifically and alters DNA-nucleosome topology.

Subunit:
Component of SWI/SNF chromatin remodeling complexes, in some of which it can be mutually exclusive with ARID1A/BAF250A. Component of the BAF (SWI/SNF-A) complex, which includes at least actin (ACTB), ARID1A, ARID1B/BAF250, SMARCA2, SMARCA4/BRG1/BAF190A, ACTL6A/BAF53, ACTL6B/BAF53B, SMARCE1/BAF57, SMARCC1/BAF155, SMARCC2/BAF170, SMARCB1/SNF5/INI1, and one or more of SMARCD1/BAF60A, SMARCD2/BAF60B, or SMARCD3/BAF60C. In muscle cells, the BAF complex also contains DPF3. Component of the SWI/SNF-B (PBAF) complex, at least composed of SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, ACTL6A/BAF53A or ACTL6B/BAF53B, SMARCE1/BAF57, SMARCD1/BAF60A, SMARCD2/BAF60B, perhaps SMARCD3/BAF60C, SMARCC1/BAF155, SMARCC2/BAF170, PB1/BAF180, ARID2/BAF200, ARID1A/BAF250A or ARID1B/BAF250B and actin. Component of a SWI/SNF-like EPAFb complex, at least composed of SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, ACTL6A/BAF53A, SMARCE1/BAF57, SMARCD1/BAF60A, SMARCD2/BAF60B, SMARCC1/BAF155, SMARCC2/BAF170, ARID1B/BAF250B, MLLT1/ENL and actin. Component of a SWI/SNF-like complex containing ARID1A/BAF250A and ARID1B/BAF250B. Interacts through its C-terminus with SMARCA2/BRM/BAF190B and SMARCA4/BRG1/BAF190A. Interacts with SMARCC1/BAF155. Component of neural progenitors-specific chromatin remodeling complex (npBAF complex) composed of at least, ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, PHF10/BAF45A, ACTL6A/BAF53A and actin. Component of neuron-specific chromatin remodeling complex (nBAF complex) composed of at least, ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, DPF1/BAF45B, DPF3/BAF45C, ACTL6B/BAF53B and actin (By similarity).

Subcellular Location:
Nuclear.

Tissue Specificity:
Widely expressed with high levels in heart, skeletal muscle and kidney.

DISEASE:
Defects in ARID1B are the cause of mental retardation autosomal dominant type 12 (MRD12) [MIM:614562]. A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. MRD12 patients present with moderate to severe psychomotor retardation, and most show evidence of muscular hypotonia. In many patients, expressive speech is more severely affected than receptive function. Additional common findings include short stature, abnormal head shape and low-set, posteriorly rotated, and abnormally shaped ears, downslanting palpebral fissures, a bulbous nasal tip, a thin upper lip, minor teeth anomalies, and brachydactyly or single palmar creases. Autistic features are uncommon.

Similarity:
Contains 1 ARID domain.

Database links:
UniProtKB/Swiss-Prot: Q8NFD5.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.a6308.cn 北京博奧森生物技術有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
欧美另类69xxxxx| 欧美一区二区影院 | 日韩三级中文字幕 | 99久久免费看国产精品 | 欧美牲交A欧美牲交 | 中文字幕人妻偷人伦在线视频 | 永久免费不卡在线观看黄网站 | 图片区乱熟图片区小说 | 米奇奇米777第四色 国产精品免费大片 | 全黄裸片一29分钟免费真人版 | 国产亚洲欧洲人人网 | 国产99久久亚洲综合精品 | 91精品国产综合久久久久久一区黄网无码 | 欧美在线成人午夜影视 | 日本黄色视频在线观看 | 毛片女人十八以上观看 | 一级做a爱过程免费视频超级 | 午夜福利一区二区三区在线观看 | 免费又黄又裸乳的gif动态图 | 日本又黄又裸一级大黄裸片 | 一级毛片人与动免费观看 | 欧美自拍另类欧美综合图片区 | 国产未发育呦交视频 | 成人免费的性色视频网站 | 可以在线观看的黄色网址 | 国产又湿又黄又硬又刺激视频 | 亚洲AV无码一区二区二三区 | 天天躁日日躁狠狠躁日日躁黑人 | 欧美亚洲国产精品久久高清 | 亚洲精品无码av专区 | 久久国产精品自线拍免费 | 成人无遮挡免费网站视频在线观看 | 人妻人人澡人人添人人爽冫 | 日本强好片久久久久久AAA | 99久久国产精品无码专区 | 国产成人精品男人的天堂网站 | 久久久久精品国产AV无码 | 久久8精品亚洲AV无码 | 91欧美人妻白浆喷潮在线不卡 | 亚洲精品初高中精品久久自慰网站 | 少妇无码太爽了不卡视频在线看 |