亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯(lián)系我們
蜜桃羞羞小视频在线观看,美女黄频视频大全免费的
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-ARID1B/Cy7 Conjugated antibody (bs-12520R-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-12520R-Cy7
英文名稱 Rabbit Anti-ARID1B/Cy7 Conjugated antibody
中文名稱 Cy7標記的抑癌基因結合蛋白ARID1B抗體
別    名 6A3 5; ARID 1B; ARID domain containing protein 1B; AT rich interactive domain 1B (SWI1 like); AT rich interactive domain 1B; AT rich interactive domain containing protein 1B; BAF 250b; BAF250b; BRG1 associated factor 250b; BRG1 binding protein; BRG1 binding protein ELD/OSA1; BRG1 binding protein hELD/OSA1; BRIGHT; DAN 15; DAN15; Eld (eyelid)/Osa protein; ELD/OSA1; hELD/OSA1; hOsa 2; hOsa2; KIAA1235; OSA 2; Osa homolog 2; OSA2; OTTHUMP00000040115; p250R; RP11 419L10.1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  結合蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Sheep, )
產品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 236kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ARID1B
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2 alpha) and Brg-1 (also designated SNF2 beta) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits, such as BAF250 (p270 or ARID 1A) and BAF250b(ARID1B), are thought to play regulatory roles.

Function:
ARID1B (AT-rich interactive domain-containing protein 1B) is a component of SWI/SNF chromatin remodeling complexes involved in transcriptional activation and repression of select genes by chromatin remodeling. It binds DNA non-specifically and alters DNA-nucleosome topology.

Subunit:
Component of SWI/SNF chromatin remodeling complexes, in some of which it can be mutually exclusive with ARID1A/BAF250A. Component of the BAF (SWI/SNF-A) complex, which includes at least actin (ACTB), ARID1A, ARID1B/BAF250, SMARCA2, SMARCA4/BRG1/BAF190A, ACTL6A/BAF53, ACTL6B/BAF53B, SMARCE1/BAF57, SMARCC1/BAF155, SMARCC2/BAF170, SMARCB1/SNF5/INI1, and one or more of SMARCD1/BAF60A, SMARCD2/BAF60B, or SMARCD3/BAF60C. In muscle cells, the BAF complex also contains DPF3. Component of the SWI/SNF-B (PBAF) complex, at least composed of SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, ACTL6A/BAF53A or ACTL6B/BAF53B, SMARCE1/BAF57, SMARCD1/BAF60A, SMARCD2/BAF60B, perhaps SMARCD3/BAF60C, SMARCC1/BAF155, SMARCC2/BAF170, PB1/BAF180, ARID2/BAF200, ARID1A/BAF250A or ARID1B/BAF250B and actin. Component of a SWI/SNF-like EPAFb complex, at least composed of SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, ACTL6A/BAF53A, SMARCE1/BAF57, SMARCD1/BAF60A, SMARCD2/BAF60B, SMARCC1/BAF155, SMARCC2/BAF170, ARID1B/BAF250B, MLLT1/ENL and actin. Component of a SWI/SNF-like complex containing ARID1A/BAF250A and ARID1B/BAF250B. Interacts through its C-terminus with SMARCA2/BRM/BAF190B and SMARCA4/BRG1/BAF190A. Interacts with SMARCC1/BAF155. Component of neural progenitors-specific chromatin remodeling complex (npBAF complex) composed of at least, ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, PHF10/BAF45A, ACTL6A/BAF53A and actin. Component of neuron-specific chromatin remodeling complex (nBAF complex) composed of at least, ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, DPF1/BAF45B, DPF3/BAF45C, ACTL6B/BAF53B and actin (By similarity).

Subcellular Location:
Nuclear.

Tissue Specificity:
Widely expressed with high levels in heart, skeletal muscle and kidney.

DISEASE:
Defects in ARID1B are the cause of mental retardation autosomal dominant type 12 (MRD12) [MIM:614562]. A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. MRD12 patients present with moderate to severe psychomotor retardation, and most show evidence of muscular hypotonia. In many patients, expressive speech is more severely affected than receptive function. Additional common findings include short stature, abnormal head shape and low-set, posteriorly rotated, and abnormally shaped ears, downslanting palpebral fissures, a bulbous nasal tip, a thin upper lip, minor teeth anomalies, and brachydactyly or single palmar creases. Autistic features are uncommon.

Similarity:
Contains 1 ARID domain.

Database links:
UniProtKB/Swiss-Prot: Q8NFD5.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.a6308.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
精品国产90后在线观看 | 91麻豆国产精品91久久久 | 国产综合色香蕉精品五夜婷 | 久久精品人妻综合AV | 高h肉肉免费全部视频观看 bbbbbxxxxx精品人 | 久久久精品国产亚洲AV综合 | 小明精品国产一区二区三区 | 国产美女流白浆的免费视 | 日韩免费一区二区三区在线 | 国精产品999一区二区三区有限 | 无遮无挡试看120秒动态图 | 正在播放国产Av国模私拍 | 久久精品无码日韩国产不卡 | 国产精品白浆无码流出.在线观看 | 无码AV动漫精品一区二区免费 | 最新国产麻豆精品 | 国产伦精品一区二区三区妓女 | 波多野结衣AV在线播放 | 有码中文无码中文无码人妻 | 国产一级精品免费看高清99 | 日本BBW丰满牲交片 国产精品国产三级国产AV剧情 | 中文字幕久久精品无码综合网 | 中文字幕国产精品高潮呻吟久久av无码 | 一级欧美一级日韩 | 风流少妇又紧又爽又丰满 | 天堂网www天堂在线中文 | 日韩欧美高清色码 | 午夜国产精品a小视频 | 欧美日韩亚洲中文字幕一区二区三区 | 国产精品久久久久精品一级APP | 亚洲 色无码专区在线 | 中国女人精69xxxxxx视频 | 一级毛片免费在线观看网站 | 亚洲精品天天影视综合网 | 精品国产成人亚洲午夜福利 | 国产精品k频道在线看 | 男女后进式猛烈XX00动态图片 | 日韩大片在线永久免费观看网站 | 一本精品99久久精品66不卡婷婷 | 最近的中文字幕在线看视频 | 中文精品字幕国产91久久久久久黄无码 |