亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯(lián)系我們
玩弄chinese丰满人妻videos,午夜国产精品a小视频
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-phospho-Ephexin-1 (Tyr179)/PE-Cy3 Conjugated antibody (bs-13084R-PE-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13084R-PE-Cy3
英文名稱 Rabbit Anti-phospho-Ephexin-1 (Tyr179)/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標記的磷酸化神經細胞鳥苷酸置換因子Ephexin1抗體
別    名 Ephexin-1 (phospho Y179); p-Ephexin-1 (phospho Y179); ARHGEF27; Eph-interacting exchange protein; EPHEXIN; Ephexin 1; Neuronal guanine nucleotide exchange factor; Ngef; NGEF_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產品類型 磷酸化抗體 
研究領域 細胞生物  神經生物學  信號轉導  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 82kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human Ephexin-1 around the phosphorylation site of Tyr179
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
EPHEXIN is a 710 amino acid protein that localizes to both the membrane and the cytoplasm and contains one SH3 domain, one PH domain and one DH domain. Expressed at high levels in brain and present at lower levels in lung tissue, EPHEXIN interacts with EphA4 and functions as a guanine nucleotide exchange factor (GEF) that is capable of activating Rho A, Rac 1 and Cdc42 and is thought to play a role in axon guidance and growth cone collapse. EPHEXIN is subject to Src-dependent phosphorylation, an event that increases the GEF activity of EPHEXIN toward Rho A. Human EPHEXIN, which exists as multiple alternatively spliced isoforms, shares a high degree of sequence homology with its mouse counterpart, suggesting a conserved role between species.

Function:
Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1-and CDC42-stimulated growth cone extension.

Subunit:
Interacts with CDK5R1 and EPHA4; activated by EPHA4 through the CDK5 kinase.

Subcellular Location:
Cytoplasm. Membrane. Cell projection, growth cone. Associated with membranes. Localizes to axonal growth cones.

Tissue Specificity:
Highly expressed in brain specifically in caudate nucleus and to a lower extent in amygdala and hippocampus. Also detected in lung.

Post-translational modifications:
Src-dependent phosphorylation at Tyr-179 upon EPHA4 activation increases the guanine exchange factor activity toward RHOA.

Similarity:
Contains 1 DH (DBL-homology) domain.
Contains 1 PH domain.
Contains 1 SH3 domain.
Database links : UniProtKB/Swiss-Prot: Q8N5V2.2

Database links:

Entrez Gene: 25791 Human

Entrez Gene: 53972 Mouse

Entrez Gene: 246217 Rat

Entrez Gene: 424744 Chicken

Omim: 605991 Human

SwissProt: Q8N5V2 Human

SwissProt: Q8CHT1 Mouse

SwissProt: Q5BKC9 Rat

Unigene: 97316 Human

Unigene: 435439 Mouse

Unigene: 20670 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.a6308.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
公的大龟慢慢挺进我的体内视频 | 国产成人久久精品二三区麻豆 | 青草草在线视频永久免费 | 日本老头老太XING交 | 亚洲人AV永久一区二区三区久久 | 免费播放巨茎人妖不卡片 | 美女裸免费观看网站 | 久久久久久久国产 | 国产欧美日韩综合一区在线播放 | 亚洲系列无码专区偷窥无码 | 亚洲欧洲国产综合AV无码久久 | av色欲无码人妻中文字幕 | 日本三级电影在线看 | 午夜欧美日韩精品久久久久久 | 国产亚洲一区二区三区啪 | 亚洲性夜夜综合久久麻豆 | 亚洲国产成人久久综合一区77 | 国产欧美日韩高清在线不卡 | 亚洲熟妇AV乱码在线观看 | 久久国产精品免费观看 | 岛国在线123456 | 免费国产黄线在线播放 | 人妻少妇精品无码专区二区 | 国产精品亚洲综合日韩在线 | 欧美综合中文字幕久久99 | 成人午夜精品网站在线观看 | 国产乱子经典视频在线观看 | 久久久精品2019免费观看 | 中文字幕无码精品久久久 | 岛国在线123456 | AV无码人妻一区二区三区在线 | 国产男女性潮高清免费网站 | 日本产品和韩国产品哪个好99 | 天天影视色香欲综合久久 | 九九精品免费观看在线 | 91久久精品日日躁夜夜躁欧美 | 最新国产精品好看的国产精品 | 国产免费AV片在线播放唯爱网 | 国产剧情AV不卡在线观看 | 文中字幕一区二区三区视频播放 | 国产啪精品视频网免费 |