亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯(lián)系我們
无码人妻免费一区二区三区,天堂在线中文一区2区,亚洲日韩一区在线观看
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-FBXO9/AP Conjugated antibody (bs-13165R-AP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13165R-AP
英文名稱 Rabbit Anti-FBXO9/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的F-box蛋白9抗體
別    名 Cross-immune reaction antigen 1; dJ341E18.2; DKFZp434C0118; F-box only protein 9; Fbp24; FBX9; FBX9_HUMAN; Fbxo9; KIAA0936; NY REN 57; OTTHUMP00000016628; OTTHUMP00000016629; OTTHUMP00000214588; Renal carcinoma antigen NY-REN-57; VCIA1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, Chimpanzee, Xenopus laevis)
產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FBX09
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates at least 3 transcript variants diverging at the 5' terminus. [provided by RefSeq, Jul 2008].

Function:
Substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of TTI1 and TELO2 in a CK2-dependent manner, thereby directly regulating mTOR signaling. SCF(FBXO9) recognizes and binds mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, the SCF(FBXO9) does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is activated due to the relief of feedback inhibition by mTORC1.

Subunit:
Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBXO9) composed of CUL1, SKP1, RBX1 and FBXO9. Interacts with TTI1 and TELO2; when TTI1 and TELO2 are phosphorylated by CK2.

Subcellular Location:
Cytoplasm.

Similarity:
Contains 1 F-box domain.
Contains 1 TPR repeat.

Database links:

Entrez Gene: 421895 Chicken

Entrez Gene: 511798 Cow

Entrez Gene: 26268 Human

Entrez Gene: 71538 Mouse

Entrez Gene: 300849 Rat

Entrez Gene: 325469 Zebrafish

Omim: 609091 Human

SwissProt: Q3ZBT2 Cow

SwissProt: Q9UK97 Human

SwissProt: Q8BK06 Mouse

SwissProt: Q5U2X1 Rat

SwissProt: Q6DG26 Zebrafish

SwissProt: Q6P3K3 Zebrafish



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.a6308.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
免费观看AV片在线播放 | 人妻性奴波多野结衣无码 | 日韩免费一级毛片 | 精品亚洲A∨无码一区二区三区 | 免费无码高潮流白浆视频 | 亚洲精品在线免费 | 69日本xxxxxxxx78 | 午夜亚洲国产理论片一二三四 | 国产AV电影区二区三区曰曰骚网 | 久久99精品久久久久久园产越南 | 搡老熟女老女人一区二区三区 | 日韩精品免费一区二区 | 最新黄色网址在线观看 | 曰本a级毛片无卡免费视频 自拍偷区亚洲综合第一页欧18 | 又长又大又粗又硬3p免费视频 | 久久九九久精品国产综合 | 亚洲中文字幕在线第六区 | 精品无码国产拍自产拍在线 | 久久精品国产亚洲成人AV未满十八站 | 国产精品你当然比游戏重要 | 人妻体内射精一区二区 | 国产美女视频免费观看的网站 | 欧美一级又粗又大又黑 | 亚洲AV无码一二区三区在线播放 | 按摩媚药无码中文字幕 | 国产V片在线播放免费无码 日韩在线视频一区二区三区 | 免费精品一区二区三区在线观看 | 国产精品无码AV片在线专区 | 国产精品天天影视久久综合网 | 久久久久久久国产免费看 | 欧美一级毛片在播放免费 | 国产成人精品一区二区免费 | 亚洲人人夜夜澡人人爽 | 精品久久久久久无码人妻热蜜芽 | 亚洲调教自慰喷水AV无码 | 艺校水嫩漂亮得2美女 | 欧美三级免费网站 | 久热香蕉在线爽青青 | 国产精品亚洲成人久久免费看 | 精品一级毛片免费视频 | 欧美a级成人淫片免费看日韩三级一级 |