亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
91极品女神私人尤物在线播放 ,久久另类精品欧美日韩高清精品不卡,99RE久久精品国产
Rabbit Anti-FBXO9/FITC Conjugated antibody (bs-13165R-FITC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-13165R-FITC
英文名稱 Rabbit Anti-FBXO9/FITC Conjugated antibody
中文名稱 FITC標(biāo)記的F-box蛋白9抗體
別    名 Cross-immune reaction antigen 1; dJ341E18.2; DKFZp434C0118; F-box only protein 9; Fbp24; FBX9; FBX9_HUMAN; Fbxo9; KIAA0936; NY REN 57; OTTHUMP00000016628; OTTHUMP00000016629; OTTHUMP00000214588; Renal carcinoma antigen NY-REN-57; VCIA1.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, Chimpanzee, Xenopus laevis)
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FBX09
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates at least 3 transcript variants diverging at the 5' terminus. [provided by RefSeq, Jul 2008].

Function:
Substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of TTI1 and TELO2 in a CK2-dependent manner, thereby directly regulating mTOR signaling. SCF(FBXO9) recognizes and binds mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, the SCF(FBXO9) does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is activated due to the relief of feedback inhibition by mTORC1.

Subunit:
Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBXO9) composed of CUL1, SKP1, RBX1 and FBXO9. Interacts with TTI1 and TELO2; when TTI1 and TELO2 are phosphorylated by CK2.

Subcellular Location:
Cytoplasm.

Similarity:
Contains 1 F-box domain.
Contains 1 TPR repeat.

Database links:

Entrez Gene: 421895 Chicken

Entrez Gene: 511798 Cow

Entrez Gene: 26268 Human

Entrez Gene: 71538 Mouse

Entrez Gene: 300849 Rat

Entrez Gene: 325469 Zebrafish

Omim: 609091 Human

SwissProt: Q3ZBT2 Cow

SwissProt: Q9UK97 Human

SwissProt: Q8BK06 Mouse

SwissProt: Q5U2X1 Rat

SwissProt: Q6DG26 Zebrafish

SwissProt: Q6P3K3 Zebrafish



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
欧美日本高清动作片www网站 | 2021av一二三级视频在线观看亚洲 | 裸露双乳挤奶无遮掩裸体私房视频 | 爽死你个放荡粗暴小淫货漫画 | 13小箩利无码视频网站免费 | 国产乱熟肥女视频网站 | 中文字幕人妻无码系列第三区 | WWW国产精品内射老熟女 | 狠狠综合久久AV一区二区三区 | 欧美一区二区三区免费视频 | 中文字幕在线视频一区 | 日本大胆欧美人术艺术 | 久久毛片免费看一区二区三区 | 国产成人精品午夜福利在线播放 | 国产MD视频一区二区三区 | 久久精品动漫99国产精品动漫 | 亚洲最大的熟女水蜜桃AV网站 | 午夜精品久久久内射近拍高清 | 国内精品人妻色欲无码久久久 | 国产SUV精品一区二区 | 性欧美video另类hd尤物 | 国产精品人人爽人人做我的可爱 | 青青草国产成人久久91网 | 欧美性猛交XXXX乱大交3 | 我两腿被同学摸的直流水 | 波多野结衣AV在线播放 | 欧美日韩一区二区三区人妻 | 麻豆一区二区在我观看 | 国内精品一区二区综合欧美 | YW193.CAN尤物国产在线网页 | 天堂网www天堂在线中文 | 最近最新的中文字幕国语在线 | 成人国产一区二区精品小说 | 最近高清中文字幕无吗免费看 | 放荡女同老师和女同学生 | 日韩欧美一区二区三区久久婷婷 | 黄色在线观看www | 国产性VIDEOSGRATIS喷潮 | 国产精品无码免费专区午夜 | 欧美精品黄页在线观看视频 | 亚洲中文乱伦无码免费看 |