亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
内射一区二区精品视频在线观看 ,91免费视频网站,香蕉有码在线视频发布
Rabbit Anti-FBXO9/Cy5 Conjugated antibody (bs-13165R-Cy5)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-13165R-Cy5
英文名稱 Rabbit Anti-FBXO9/Cy5 Conjugated antibody
中文名稱 Cy5標(biāo)記的F-box蛋白9抗體
別    名 Cross-immune reaction antigen 1; dJ341E18.2; DKFZp434C0118; F-box only protein 9; Fbp24; FBX9; FBX9_HUMAN; Fbxo9; KIAA0936; NY REN 57; OTTHUMP00000016628; OTTHUMP00000016629; OTTHUMP00000214588; Renal carcinoma antigen NY-REN-57; VCIA1.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  泛素  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, Chimpanzee, Xenopus laevis)
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FBX09
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates at least 3 transcript variants diverging at the 5' terminus. [provided by RefSeq, Jul 2008].

Function:
Substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of TTI1 and TELO2 in a CK2-dependent manner, thereby directly regulating mTOR signaling. SCF(FBXO9) recognizes and binds mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, the SCF(FBXO9) does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is activated due to the relief of feedback inhibition by mTORC1.

Subunit:
Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBXO9) composed of CUL1, SKP1, RBX1 and FBXO9. Interacts with TTI1 and TELO2; when TTI1 and TELO2 are phosphorylated by CK2.

Subcellular Location:
Cytoplasm.

Similarity:
Contains 1 F-box domain.
Contains 1 TPR repeat.

Database links:

Entrez Gene: 421895 Chicken

Entrez Gene: 511798 Cow

Entrez Gene: 26268 Human

Entrez Gene: 71538 Mouse

Entrez Gene: 300849 Rat

Entrez Gene: 325469 Zebrafish

Omim: 609091 Human

SwissProt: Q3ZBT2 Cow

SwissProt: Q9UK97 Human

SwissProt: Q8BK06 Mouse

SwissProt: Q5U2X1 Rat

SwissProt: Q6DG26 Zebrafish

SwissProt: Q6P3K3 Zebrafish



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
国产麻豆剧传媒精品国产AV | 中国性少妇内射XXXX狠干 | 性欧美大战久久久久久久黑人 | 国产午夜亚洲精品国产 | a久久久久一级毛片护士免费 | 国产高清国内精品福利色噜噜 | 影音先锋av男人资源 | 人妻人人澡人人添人人爽冫 | 亚洲欧美日韩在线不卡 | 可以在线看av的网站 | 超嫩校花被灌醉在线观看 | 欧美va亚洲va在线观看不卡 | 久久久久久久成人午夜精品福利 | 亚洲乱码国产乱码精品精乡村 | 亚洲无码在线观看视频 | 97精品国产高清自在线看超 | 男JI大巴进入女人的视频 | 高清一区二区三区日本久 | 麻豆蜜桃国产精品无码视频 | 在线免费观看毛片 | 久久人人爽人人澡人人高潮av | 亚洲第一区第二区 | 久久久久久亚洲av无码专区 | 婷婷射精AV这里只有精品 | 456亚洲人成影院在线观 | 中文字幕在线一区二区三区 | 美女被C污黄网站免费观看 又粗又硬女人免费视频 | 内射白嫩少妇超碰 | 久久人人妻人人爽人人爽 | 欧美性猛交XXXX乱大交极品 | 久久久精品日韩免费观看 | 屁屁国产第1页草草影院 | 国产a视频精品免费观看 | 亚洲国产成人精品无码av不卡久久久久 | 插插射啊爱视频日A级 | 宝贝别忍着喷出来嗯啊哦漫画 | 四虎影视成人永久免费观看视频 | 国产日产欧美一区二区蜜桃 | 天堂AV成人无码久久免费精品 | 中文无码AV人妻一级字幕VR | 久久精品天天爽夜夜爽 |