亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
少妇高潮灌满白浆毛片免费看,无码av中文字幕免费放
Rabbit Anti-FBXO9/PE-Cy5 Conjugated antibody (bs-13165R-PE-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-13165R-PE-Cy5
英文名稱 Rabbit Anti-FBXO9/PE-Cy5 Conjugated antibody
中文名稱 PE-Cy5標(biāo)記的F-box蛋白9抗體
別    名 Cross-immune reaction antigen 1; dJ341E18.2; DKFZp434C0118; F-box only protein 9; Fbp24; FBX9; FBX9_HUMAN; Fbxo9; KIAA0936; NY REN 57; OTTHUMP00000016628; OTTHUMP00000016629; OTTHUMP00000214588; Renal carcinoma antigen NY-REN-57; VCIA1.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, Chimpanzee, Xenopus laevis)
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FBX09
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates at least 3 transcript variants diverging at the 5' terminus. [provided by RefSeq, Jul 2008].

Function:
Substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of TTI1 and TELO2 in a CK2-dependent manner, thereby directly regulating mTOR signaling. SCF(FBXO9) recognizes and binds mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, the SCF(FBXO9) does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is activated due to the relief of feedback inhibition by mTORC1.

Subunit:
Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBXO9) composed of CUL1, SKP1, RBX1 and FBXO9. Interacts with TTI1 and TELO2; when TTI1 and TELO2 are phosphorylated by CK2.

Subcellular Location:
Cytoplasm.

Similarity:
Contains 1 F-box domain.
Contains 1 TPR repeat.

Database links:

Entrez Gene: 421895 Chicken

Entrez Gene: 511798 Cow

Entrez Gene: 26268 Human

Entrez Gene: 71538 Mouse

Entrez Gene: 300849 Rat

Entrez Gene: 325469 Zebrafish

Omim: 609091 Human

SwissProt: Q3ZBT2 Cow

SwissProt: Q9UK97 Human

SwissProt: Q8BK06 Mouse

SwissProt: Q5U2X1 Rat

SwissProt: Q6DG26 Zebrafish

SwissProt: Q6P3K3 Zebrafish



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
内射毛片内射国产夫妻 | 无码精品人妻一区二区三区涩爱 | 内射人妻无套中出无码 | 荡娃艳妇有声小说 | 亚洲精品无码久久久久 | 91精品国产制服啪啪无码 | 中文字幕一区视频一线 | 欧洲无人区卡一卡二卡三 | jizz国产丝袜18老师美女 | 久久成人国产精品麻豆 | 成人满18在线观看网站免费 | 一级黄色毛片播放 | 中文字幕日本最新乱码视频 | 丝袜情趣在线资源二区 | 日韩黄色免费观看 | 美女用震蛋叫爽的视频95视频 | 免费无码高潮又爽又刺激久久AⅤ | 中文字幕在线免费观看视频 | 亚洲无码总合另类中文字幕 | 亚裔美女被黑人巨大进入 | 中文字幕网伦射乱中文 | 国产欧美一区二区三区视频 | 免费播放一区二区三区 | 丰满肥妇BBWBBWBBWBBW | 免费午夜扒丝袜www在线看 | 国产拍揄自揄免费观看 | 国产精品宾馆精品酒店 | 国产国产a在线高清观看 | 中文字幕无线码免费人妻 | 国产97人人超碰cao蜜芽国产 | 国产成人精选视频在线观看不卡 | 亚州日本乱码一区二区三区 | 97se亚洲综合自在线尤物 | 天堂网在线最新版www | 国产又黄又爽又猛免费app | 亚洲日韩精品欧美一区二区一 | 亚洲日韩在线中文字幕一区 | 久久99蜜桃精品久久久久小说 | 中文字幕va一区二区三区 | 久久久久久久国产免费看 | gvg454真实性教育在线播放 |