亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
你的欲梦裸身在线播放,深夜久久AAAAA级毛片免费看,亚洲熟妇一区二区三区
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-FBXO9/BF555 Conjugated antibody (bs-13165R-BF555)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-13165R-BF555
英文名稱 Rabbit Anti-FBXO9/BF555 Conjugated antibody
中文名稱 BF555標記的F-box蛋白9抗體
別    名 Cross-immune reaction antigen 1; dJ341E18.2; DKFZp434C0118; F-box only protein 9; Fbp24; FBX9; FBX9_HUMAN; Fbxo9; KIAA0936; NY REN 57; OTTHUMP00000016628; OTTHUMP00000016629; OTTHUMP00000214588; Renal carcinoma antigen NY-REN-57; VCIA1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細胞生物  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, Chimpanzee, Xenopus laevis)
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FBX09
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates at least 3 transcript variants diverging at the 5' terminus. [provided by RefSeq, Jul 2008].

Function:
Substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of TTI1 and TELO2 in a CK2-dependent manner, thereby directly regulating mTOR signaling. SCF(FBXO9) recognizes and binds mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, the SCF(FBXO9) does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is activated due to the relief of feedback inhibition by mTORC1.

Subunit:
Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBXO9) composed of CUL1, SKP1, RBX1 and FBXO9. Interacts with TTI1 and TELO2; when TTI1 and TELO2 are phosphorylated by CK2.

Subcellular Location:
Cytoplasm.

Similarity:
Contains 1 F-box domain.
Contains 1 TPR repeat.

Database links:

Entrez Gene: 421895 Chicken

Entrez Gene: 511798 Cow

Entrez Gene: 26268 Human

Entrez Gene: 71538 Mouse

Entrez Gene: 300849 Rat

Entrez Gene: 325469 Zebrafish

Omim: 609091 Human

SwissProt: Q3ZBT2 Cow

SwissProt: Q9UK97 Human

SwissProt: Q8BK06 Mouse

SwissProt: Q5U2X1 Rat

SwissProt: Q6DG26 Zebrafish

SwissProt: Q6P3K3 Zebrafish



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
久久久无码精品一区二区三区 | 婷婷无套内射影院 | 国产精品亚洲第一区在线 | 国产91在线精品国自产在线 | 亚洲综合色区另类aV无码 | 欧美日韩一区在线观看 | 影音先锋国产精品网站 | 丰满老熟好大bbb | 香蕉有码在线视频发布 | 免费无码精品黄AV电影 | 内射后入蘑菇视频ONLYYOU | 国产精品自产拍在线观看中文 | 超碰97人人做人人爱亚洲尤物 | 永久黄网站色视频免费观看 | 人人看人人摸人人操637 | 亚洲无线一二三四区手机 | 理论片87福利理论电影 | 人妖和人妖互交性XXXX视频 | 又紧又大又爽精品一区二区 | 久久精品中文字幕无码有码 | 中文字幕无码一区二区免费 | 国产一卡 二卡三卡四卡无卡乱码视频 | 调教我的妺妺H肉YIN荡视频 | 欧美激情一区二区三区蜜桃视频 | 青青草原综合久久大伊人精品 | 国产AV国片精品一区二区 | 久久婷婷国产剧情内射白浆 | 精品国产亚洲AV麻豆 | 性奴抽插乳中出精没射视频搜索 | 欧美在线成人午夜影视 | 亚洲精品无码久久久久久久久 | 国产V片在线播放免费观看大全 | 可以在线看av的网站 | 一性一交一伦一色一按—摩 | JLZZJLZZ亚洲乱熟在线播放 | 国产麻豆91网在线看 | 久久久无码精品一区二区三区 | 日本少妇AA一级特黄大片 | 熟女少妇内射日韩亚洲 | 成人免费精品网站在线观看影片 | 亚洲黄色网站免费观看 |